Future of Personalized Medicine in Oncology: A Systems Biology Approach

Targeting cancer-specific synthetic lethality in double-strand DNA break repair

(2011) Benjamin J. Moeller et al.   CELL CYCLE

The Potential of PARP Inhibitors in Genetic Breast and Ovarian Cancers

(2009) Yvette Drew et al.   Annals of the New York Academy of Sciences

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

(2009) B. T. Hennessy et al.   CANCER RESEARCH

A Systems Approach to Analysis of Molecular Complexity in Breast Cancer

(2009) B. T. Hennessy et al.   CLINICAL CANCER RESEARCH

DNA methylation and cancer diagnosis: new methods and applications

(2009) Pierre Dehan et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

KRAS Mutations and Sensitivity to Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer: Practical Application of Patient Selection

(2009) Antonio Jimeno et al.   JOURNAL OF CLINICAL ONCOLOGY

Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates

(2009) S. E. Woodman et al.   MOLECULAR CANCER THERAPEUTICS

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor dormancy and oncogene addiction 

(2008) DEAN W. FELSHER   APMIS

An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer

(2008) K. Stemke-Hale et al.   CANCER RESEARCH

Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance

(2008) N. T. Ihle et al.   CANCER RESEARCH

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

(2008) Jeffrey A Engelman et al.   NATURE MEDICINE

Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer

(2008) Liqiang Xi et al.   NUCLEIC ACIDS RESEARCH

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

(2008) R. J. Leary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA