4.7 Article

Evidence of a Recombinant Wild-Type Human Astrovirus Strain from a Kenyan Child with Gastroenteritis

期刊

JOURNAL OF CLINICAL MICROBIOLOGY
卷 49, 期 2, 页码 728-731

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AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.01093-10

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资金

  1. National Research Foundation
  2. Department of Medical Virology, University of Pretoria, Pretoria, South Africa
  3. Institute of Primate Research (IPR)
  4. Kenya Medical Research Institute (KEMRI) (Kenya)

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A human astrovirus (HAstV) strain from Kenya was characterized by nucleotide sequence analysis. Sequences from open reading frame 1a (ORF1a) clustered with genotype 6/7, those from ORF1b clustered with genotype 3, and those from ORF2 clustered with genotype 2. A recombination point in the ORF1b-ORF2 junction was identified, with a second possible recombination point within the ORF1a region.

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