Article
Cardiac & Cardiovascular Systems
Bizhong Che, Chongke Zhong, Ruijie Zhang, Liyuan Pu, Tian Zhao, Yonghong Zhang, Liyuan Han
Summary: The triglyceride-glucose (TyG) index and triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio, two simple surrogate indicators of insulin resistance, are associated with an increased risk of cardiovascular disease (CVD) in European populations. The elevated risk is largely mediated by a higher prevalence of dyslipidemia, type 2 diabetes, and hypertension.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Medicine, General & Internal
Yolanda Martinez-Marroquin, Alejandra Meaney, Virginia Samaniego-Mendez, Nayelli Najera, Guillermo Ceballos, Carlos Fernandez-Barros, Eduardo Meaney
Summary: The study examines the TG/HDL-c ratio as a cardiovascular risk marker in a middle-class urban Mexican population. The Lindavista score (LS) is developed based on multiple variables and shows correlation with high-risk categories. Compared to the ACC ASCVD system, the TG/HDL-c ratio provides more accurate assessment of high-risk categories.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
Aya Higashiyama, Ichiro Wakabayashi, Tomonori Okamura, Yoshihiro Kokubo, Makoto Watanabe, Misa Takegami, Kyoko Honda-Kohmo, Akira Okayama, Yoshihiro Miyamoto
Summary: A prospective cohort study in a Japanese urban general population found that fasting triglyceride is an independent predictor for ischemic cardiovascular disease, especially when TG levels are below 400 mg/dL. The cardiometabolic index may be the most powerful predictor for ischemic CVD among TG, TG/HDL-C, and other indices.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2021)
Review
Pharmacology & Pharmacy
Fang Yang, Nana Li, Mihnea-Alexandru Gaman, Ning Wang
Summary: The study found that raloxifene can significantly increase high-density lipoprotein cholesterol levels in women, while significantly reducing total cholesterol and low-density lipoprotein cholesterol levels. Additionally, a significant decrease in serum triglycerides levels can be observed with raloxifene treatment duration of <= 26 weeks and baseline TG concentrations of <= 130 mg/dL.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
Dong Hyuk Jung, Byoungjin Park, Ha Eun Ryu, Yong Jae Lee
Summary: The GGT/HDL-C ratio is related to the risk of cardiovascular disease in women, especially in metropolitan areas. This ratio may serve as a useful predictive marker for cardiovascular disease.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Environmental Sciences
Kai Zhao, Jing Li, Chaonan Du, Qiang Zhang, Yu Guo, Mingfei Yang
Summary: Ambient PM2.5 is significantly associated with the risk of HS, potentially a risk factor for HS. Smoking does not further increase the risk of HS under exposure to PM2.5.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Medicine, General & Internal
Arcangelo Iannuzzi, Francesco Giallauria, Marco Gentile, Paolo Rubba, Giuseppe Covetti, Alessandro Bresciani, Emilio Aliberti, Gilanluigi Cuomo, Camilla Panico, Maria Tripaldella, Maria Ausilia Giusti, Alessandro Mattina, Gabriella Iannuzzo
Summary: This study aimed to evaluate the association between lipid parameters and subclinical atherosclerosis. The results showed a significant association between the non-HDL-C/HDL-C ratio and carotid intima-media thickness, as well as a strong correlation with VLDL-C levels.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Public, Environmental & Occupational Health
Yemataw Gelaw, Zegeye Getaneh, Mulugeta Melku
Summary: Through analysis of 17 articles, it was found that the odds of tuberculosis among anemic patients were 3.56 times higher than non-anemic patients. Cohort studies showed that the hazard ratio of tuberculosis was 2.01 times higher among anemic patients. Additionally, the risk of tuberculosis increased with the severity of anemia.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2021)
Article
Clinical Neurology
Anran Wang, Yapeng Li, Lue Zhou, Kai Liu, Shaohua Li, Ce Zong, Bo Song, Yuan Gao, Yusheng Li, Chuansheng Tian, Yurong Xing, Yuming Xu, Longde Wang
Summary: The non-HDL-C/HDL-C ratio was found to be significantly associated with carotid plaque stability and may serve as a useful indicator for early identification of high-risk carotid plaque.
FRONTIERS IN NEUROLOGY
(2022)
Review
Medicine, General & Internal
Pablo Ortiz de Urbina Comeron, Alvaro Zubizarreta-Macho, Ana Belen Lobo Galindo, Jose Maria Montiel-Company, Maria-Fernanda Lorenzo-Gomez, Javier Flores Fraile
Summary: This systematic review and meta-analysis found that the incidence of periodontal disease does not increase the risk of prostate inflammation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Jiajun Qiu, Maobin Kuang, Ruijuan Yang, Changhui Yu, Shiming He, Guotai Sheng, Yang Zou
Summary: This study found a significant positive association between the ALT/HDL-C ratio and NAFLD, suggesting that the ALT/HDL-C ratio can effectively identify individuals with NAFLD.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Song Lu, Maobin Kuang, Jinjing Yue, Chong Hu, Guotai Sheng, Yang Zou
Summary: In the Japanese population, non-traditional lipid indicators had a higher diagnostic value for NAFLD compared to traditional lipid indicators, with RC/HDL-C and TG/HDL-C being the best lipid indicators for identifying NAFLD.
LIPIDS IN HEALTH AND DISEASE
(2022)
Review
Obstetrics & Gynecology
Zhen Wang, Lanlan Fang, Ze Wu, Yuxi Li, Qiongqiong Jia, Jung-Chien Cheng, Ying-Pu Sun
Summary: The meta-analysis findings suggest that patients with premature ovarian insufficiency (POI) have significantly higher levels of serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride, but no significant difference in high-density lipoprotein cholesterol (HDL-C) levels compared to controls. These results indicate that elevations in unfavorable lipids may contribute to the increased risk of cardiovascular diseases observed in patients with POI.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Gastroenterology & Hepatology
Alessandro Mantovani, Graziana Petracca, Alessandro Csermely, Giorgia Beatrice, Stefano Bonapace, Andrea Rossi, Herbert Tilg, Christopher D. Byrne, Giovanni Targher
Summary: A meta-analysis of observational studies demonstrated that non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of new-onset heart failure (HF). This risk is independent of other common cardiovascular risk factors.
Review
Pharmacology & Pharmacy
Luis E. Simental-Mendia, Mario Simental-Mendia, Adriana Sanchez-Garcia, Enrique Linden-Torres
Summary: The meta-analysis results suggest that hydroxychloroquine improves lipid parameters by reducing total cholesterol, LDL-C, triglycerides, non-HDL-C, and increasing HDL-C levels in patients receiving the treatment.
CURRENT PHARMACEUTICAL DESIGN
(2021)