The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

New strategies for cancer immunotherapy: targeting regulatory T cells

(2017) Francesca Finotello et al.   Genome Medicine

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

(2016) Michael D. Buck et al.   CELL

Regulatory T cells in cancer immunotherapy

(2016) Atsushi Tanaka et al.   CELL RESEARCH

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

(2016) Romain Roncagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunometabolism of regulatory T cells

(2016) Ryan Newton et al.   NATURE IMMUNOLOGY

PI3K/Akt promotes feedforward mTORC2 activation through IKKα

(2016) Han C. Dan et al.   Oncotarget

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

(2015) R. G. Veenstra et al.   BLOOD

Mitochondrial membrane potential is regulated by vimentin intermediate filaments

(2015) Ivan S. Chernoivanenko et al.   FASEB JOURNAL

T cell metabolism drives immunity

(2015) Michael D. Buck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses

(2015) Sharad Shrestha et al.   NATURE IMMUNOLOGY

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability

(2015) Alexandria Huynh et al.   NATURE IMMUNOLOGY

Advances and challenges in immunotherapy for solid organ and hematopoietic stem cell transplantation

(2015) Cameron McDonald-Hyman et al.   Science Translational Medicine

Vimentin regulates activation of the NLRP3 inflammasome

(2015) Gimena dos Santos et al.   Nature Communications

Vimentin is involved in regulation of mitochondrial motility and membrane potential by Rac1

(2015) E. A. Matveeva et al.   Biology Open

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment

(2015) M. D. Sharma et al.   Science Advances

Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD

(2014) K. L. Lin et al.   BLOOD

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

(2014) M. F. Martelli et al.   BLOOD

Signals and pathways controlling regulatory T cells

(2014) Alexandria Huynh et al.   IMMUNOLOGICAL REVIEWS

Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II

(2014) Bitao Liang et al.   JOURNAL OF IMMUNOLOGY

In-Depth Quantitative Proteomic Analysis of de Novo Protein Synthesis Induced by Brain-Derived Neurotrophic Factor

(2014) Guoan Zhang et al.   JOURNAL OF PROTEOME RESEARCH

What Counts in the Immunological Synapse?

(2014) Michael L. Dustin   MOLECULAR CELL

Continuous requirement for the TCR in regulatory T cell function

(2014) Andrew G Levine et al.   NATURE IMMUNOLOGY

TREG-cell therapies for autoimmune rheumatic diseases

(2014) Makoto Miyara et al.   Nature Reviews Rheumatology

Effector T cells require fatty acid metabolism during murine graft-versus-host disease

(2013) C. A. Byersdorfer et al.   BLOOD

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

(2013) K. Aoyama et al.   BLOOD

IKK interacts with rictor and regulates mTORC2

(2013) Yuanfei Xu et al.   CELLULAR SIGNALLING

Development and Maintenance of Regulatory T cells

(2013) Naganari Ohkura et al.   IMMUNITY

PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis

(2013) Bernd H. Zinselmeyer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis

(2013) Greg M. Delgoffe et al.   NATURE

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function

(2013) Hu Zeng et al.   NATURE

In and out of the bull's eye: protein kinase Cs in the immunological synapse

(2013) Kok-Fai Kong et al.   TRENDS IN IMMUNOLOGY

The intermediate filament protein, vimentin, is a regulator of NOD2 activity

(2012) Craig Stevens et al.   GUT

Protein Kinase C-  Inhibits Inducible Regulatory T Cell Differentiation via an AKT-Foxo1/3a-Dependent Pathway

(2012) J. Ma et al.   JOURNAL OF IMMUNOLOGY

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Mitochondrial and Plasma Membrane Pools of Stomatin-Like Protein 2 Coalesce at the Immunological Synapse during T Cell Activation

(2012) Darah A. Christie et al.   PLoS One

Molecular Mechanisms of Treg-Mediated T Cell Suppression

(2012) Angelika Schmidt et al.   Frontiers in Immunology

Regulation of PKC-θ function by phosphorylation in T cell receptor signaling

(2012) Xiaohong Wang et al.   Frontiers in Immunology

Comparison of Three Quantitative Phosphoproteomic Strategies to Study Receptor Tyrosine Kinase Signaling

(2011) Guoan Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Vimentin intermediate filaments modulate the motility of mitochondria

(2011) Oxana E. Nekrasova et al.   MOLECULAR BIOLOGY OF THE CELL

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.

(2010) Matthias Merkenschlager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protein Kinase C-  Mediates Negative Feedback on Regulatory T Cell Function

(2010) A. Zanin-Zhorov et al.   SCIENCE

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET

Distinct Roles for CARMIL Isoforms in Cell Migration

(2009) Yun Liang et al.   MOLECULAR BIOLOGY OF THE CELL

The Actin Cytoskeleton in T Cell Activation

(2008) Janis K. Burkhardt et al.   Annual Review of Immunology

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Neuropilin-1 Expression on Regulatory T Cells Enhances Their Interactions with Dendritic Cells during Antigen Recognition

(2008) Milka Sarris et al.   IMMUNITY

Differential requirement of PKC-θ in the development and function of natural regulatory T cells

(2008) Sonal Gupta et al.   MOLECULAR IMMUNOLOGY