Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion

Induction of Thermal Hyperalgesia and Synaptic Long-Term Potentiation in the Spinal Cord Lamina I by TNF-  and IL-1  is Mediated by Glial Cells

(2013) D. Gruber-Schoffnegger et al.   JOURNAL OF NEUROSCIENCE

Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis

(2013) Francesco Ferrini et al.   NATURE NEUROSCIENCE

Caspase-6 activity predicts lower episodic memory ability in aged individuals

(2013) Jasmine Ramcharitar et al.   NEUROBIOLOGY OF AGING

Glia and pain: Is chronic pain a gliopathy?

(2013) Ru-Rong Ji et al.   PAIN

Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice

(2012) Valeria Uribe et al.   HUMAN MOLECULAR GENETICS

Priming of adult pain responses by neonatal pain experience: maintenance by central neuroimmune activity

(2011) Simon Beggs et al.   BRAIN

Resolving TRPV1- and TNF- -Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

Long-Term Potentiation in Spinal Nociceptive Pathways as a Novel Target for Pain Therapy

(2011) Ruth Ruscheweyh et al.   Molecular Pain

Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

(2011) O. Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-6 and neurodegeneration

(2011) Rona K. Graham et al.   TRENDS IN NEUROSCIENCES

The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: The role of tumor necrosis factor-α

(2010) Yi Zhong et al.   BRAIN BEHAVIOR AND IMMUNITY

Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat

(2010) Li-Jun Zhou et al.   BRAIN BEHAVIOR AND IMMUNITY

Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

(2010) Zheng Li et al.   CELL

Substance P Sensitizes P2X3 in Nociceptive Trigeminal Neurons

(2010) C.K. Park et al.   JOURNAL OF DENTAL RESEARCH

Neutrophils Activate Alveolar Macrophages by Producing Caspase-6-Mediated Cleavage of IL-1 Receptor-Associated Kinase-M

(2010) H. Kobayashi et al.   JOURNAL OF IMMUNOLOGY

Amyloid Precursor Protein Cleavage-Dependent and -Independent Axonal Degeneration Programs Share a Common Nicotinamide Mononucleotide Adenylyltransferase 1-Sensitive Pathway

(2010) B. P. S. Vohra et al.   JOURNAL OF NEUROSCIENCE

A p38 Mitogen-Activated Protein Kinase-Dependent Mechanism of Disinhibition in Spinal Synaptic Transmission Induced by Tumor Necrosis Factor- 

(2010) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

Central mechanisms of pathological pain

(2010) Rohini Kuner   NATURE MEDICINE

Interactions between the immune and nervous systems in pain

(2010) Ke Ren et al.   NATURE MEDICINE

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior

(2010) Jeong Il Choi et al.   PAIN

TNF-alpha contributes to spinal cord synaptic plasticity and inflammatory pain: Distinct role of TNF receptor subtypes 1 and 2

(2010) Ling Zhang et al.   PAIN

Chemokines, neuronal–glial interactions, and central processing of neuropathic pain

(2010) Yong-Jing Gao et al.   PHARMACOLOGY & THERAPEUTICS

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Persistent Pain Is Dependent on Spinal Mitochondrial Antioxidant Levels

(2009) E. S. Schwartz et al.   JOURNAL OF NEUROSCIENCE

P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation

(2009) T. Trang et al.   JOURNAL OF NEUROSCIENCE

Behavioral Phenotypes of Mice Lacking Purinergic P2X4 Receptors in Acute and Chronic Pain Assays

(2009) Makoto Tsuda et al.   Molecular Pain

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Current Challenges in Glia-Pain Biology

(2009) Stephen B. McMahon et al.   NEURON

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

(2008) Yasuhiko Kawasaki et al.   NATURE MEDICINE

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE