HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

Tax-Inducible Production of CC Chemokine Ligand 22 by Human T Cell Leukemia Virus Type 1 (HTLV-1)-Infected T Cells Promotes Preferential Transmission of HTLV-1 to CCR4-Expressing CD4+ T Cells

(2014) K. Hieshima et al.   JOURNAL OF IMMUNOLOGY

Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy

(2013) Hitoshi Ando et al.   BRAIN

T helper cells plasticity in inflammation

(2013) Lorenzo Cosmi et al.   CYTOMETRY PART A

CSF CXCL10, CXCL9, and Neopterin as Candidate Prognostic Biomarkers for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis

(2013) Tomoo Sato et al.   PLoS Neglected Tropical Diseases

HTLV-1 bZIP Factor Induces Inflammation through Labile Foxp3 Expression

(2013) Nanae Yamamoto-Taguchi et al.   PLoS Pathogens

HTLV-1-infected T cells contain a single integrated provirus in natural infection

(2012) L. B. Cook et al.   BLOOD

Defucosylated Anti-CCR4 Monoclonal Antibody (KW-0761) for Relapsed Adult T-Cell Leukemia-Lymphoma: A Multicenter Phase II Study

(2012) Takashi Ishida et al.   JOURNAL OF CLINICAL ONCOLOGY

HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals

(2012) Yorifumi Satou et al.   Retrovirology

Clinical Pathophysiology of Human T-Lymphotropic Virus-Type 1-Associated Myelopathy/Tropical Spastic Paraparesis

(2012) Yoshihisa Yamano et al.   Frontiers in Microbiology

Molecular mechanisms underlying the regulation and functional plasticity of FOXP3+ regulatory T cells

(2011) Y Gao et al.   GENES AND IMMUNITY

CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

(2011) S. A. Long et al.   JOURNAL OF IMMUNOLOGY

T-bet in disease

(2011) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Low CD4/CD8 T-Cell Ratio Associated with Inflammatory Arthropathy in Human T-Cell Leukemia Virus Type I Tax Transgenic Mice

(2011) Takeo Ohsugi et al.   PLoS One

Human T-Lymphotropic Virus Type 1 (HTLV-1) and Regulatory T Cells in HTLV-1-Associated Neuroinflammatory Disease

(2011) Natsumi Araya et al.   Viruses-Basel

Intra- and inter-laboratory variability in human T-cell leukemia virus type-1 proviral load quantification using real-time polymerase chain reaction assays: A multi-center study

(2010) Shimeru Kamihira et al.   CANCER SCIENCE

Immunopathogenesis of lymphoma: Focus on CCR4

(2010) Takashi Ishida et al.   CANCER SCIENCE

Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma

(2010) Kazuhito Yamamoto et al.   JOURNAL OF CLINICAL ONCOLOGY

Human T-Lymphotropic Virus Type 1-Induced CC Chemokine Ligand 22 Maintains a High Frequency of Functional FoxP3+ Regulatory T Cells

(2010) F. Toulza et al.   JOURNAL OF IMMUNOLOGY

Neuroimmunity of HTLV-I Infection

(2010) Eiji Matsuura et al.   Journal of Neuroimmune Pharmacology

Effector T cell plasticity: flexibility in the face of changing circumstances

(2010) Kenneth M Murphy et al.   NATURE IMMUNOLOGY

FOXP3+ Regulatory T Cells and T Helper 1, T Helper 2, and T Helper 17 Cells in Human Early Pregnancy Decidua1

(2009) Jenny Mjösberg et al.   BIOLOGY OF REPRODUCTION

T-bet expression is regulated by EGR1-mediated signaling in activated T cells

(2009) Hyun-Jin Shin et al.   CLINICAL IMMUNOLOGY

Plasticity of CD4+ FoxP3+ T cells

(2009) Xuyu Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Phenotypic analysis of human peripheral blood regulatory T cells (CD4+FOXP3+CD127lo/-) ex vivo and after in vitro restimulation with malaria antigens

(2009) Olivia C. Finney et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Abnormally High Levels of Virus-Infected IFN-γ+CCR4+CD4+CD25+ T Cells in a Retrovirus-Associated Neuroinflammatory Disorder

(2009) Yoshihisa Yamano et al.   PLoS One

Induction of p21CIP1/WAF1 expression by human T-lymphotropic virus type 1 Tax requires transcriptional activation and mRNA stabilization

(2009) Ling Zhang et al.   Retrovirology

Dysregulation of TGF-  signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease

(2008) C. Grant et al.   BLOOD

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD