Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Expression quantitative trait loci: present and future

(2013) A. C. Nica et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density

(2012) Cheryl L. Ackert-Bicknell et al.   BONE

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies

(2012) Alyson Ashe et al.   HUMAN MOLECULAR GENETICS

Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia

(2012) N. Qiu et al.   JOURNAL OF CELL SCIENCE

Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits

(2012) Anatole Ghazalpour et al.   MAMMALIAN GENOME

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Genetics of osteoporosis from genome-wide association studies: advances and challenges

(2012) J. Brent Richards et al.   NATURE REVIEWS GENETICS

Systems Genetic Analysis of Osteoblast-Lineage Cells

(2012) Gina Calabrese et al.   PLoS Genetics

Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia

(2011) Marine R.-C. Kraus et al.   HUMAN MUTATION

Systems Genetics

(2011) J. H. Nadeau et al.   SCIENCE

Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis

(2011) Charles R. Farber et al.   PLoS Genetics

Role of the polycytin-primary cilia complex in bone development and mechanosensing

(2010) Z.S. Xiao et al.   Annals of the New York Academy of Sciences

Osteocyte primary cilium and its role in bone mechanotransduction

(2010) Sara Temiyasathit et al.   Annals of the New York Academy of Sciences

The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment

(2010) Padmaja Tummala et al.   Cellular and Molecular Bioengineering

The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity

(2010) U. Tran et al.   DEVELOPMENT

Expression Quantitative Trait Loci: Replication, Tissue- and Sex-Specificity in Mice

(2010) A. van Nas et al.   GENETICS

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

Identification of a gene module associated with BMD through the integration of network analysis and genome-wide association data

(2010) Charles R Farber   JOURNAL OF BONE AND MINERAL RESEARCH

BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat

(2010) Wesley G Beamer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map

(2010) Cheryl L Ackert-Bicknell et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits

(2010) Yi-Hsiang Hsu et al.   PLoS Genetics

Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow

(2009) C. Maisonneuve et al.   DEVELOPMENT

Bicaudal C and trailer hitch have similar roles in gurken mRNA localization and cytoskeletal organization

(2009) Mark J. Snee et al.   DEVELOPMENTAL BIOLOGY

Conditional Disruption ofPkd1in Osteoblasts Results in Osteopenia Due to Direct Impairment of Bone Formation

(2009) Zhousheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Future of Osteoporosis Genetics: Enhancing Genome-Wide Association Studies

(2009) Charles R Farber et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

(2009) Xia Yang et al.   NATURE GENETICS

Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling

(2009) Charles R. Farber et al.   PHYSIOLOGICAL GENOMICS

A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia

(2009) Christopher L. Plaisier et al.   PLoS Genetics

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Using genetic markers to orient the edges in quantitative trait networks: The NEO software

(2008) Jason E Aten et al.   BMC Systems Biology

Genetic Variation in Candidate Osteoporosis Genes, Bone Mineral Density, and Fracture Risk: The Study of Osteoporotic Fractures

(2008) Gregory J. Tranah et al.   CALCIFIED TISSUE INTERNATIONAL

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS

Polycystin-1 Regulates Skeletogenesis through Stimulation of the Osteoblast-specific Transcription FactorRUNX2-II

(2008) Zhousheng Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARG by Dietary Fat Interaction Influences Bone Mass in Mice and Humans

(2008) Cheryl L Ackert-Bicknell et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An Integrative Genetics Approach to Identify Candidate Genes Regulating BMD: Combining Linkage, Gene Expression, and Association

(2008) Charles R Farber et al.   JOURNAL OF BONE AND MINERAL RESEARCH

K Homology Domains of the Mouse Polycystic Kidney Disease-Related Protein, Bicaudal-C (Bicc1), Mediate RNA Binding in vitro

(2008) Denise J. Bouvrette et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Model-based variance-stabilizing transformation for Illumina microarray data

(2008) Simon M. Lin et al.   NUCLEIC ACIDS RESEARCH

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

Geometric Interpretation of Gene Coexpression Network Analysis

(2008) Steve Horvath et al.   PLoS Computational Biology