Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility

IL-20 Receptor 2 Signaling Down-Regulates Antigen-Specific T Cell Responses

(2014) C. Wahl et al.   JOURNAL OF IMMUNOLOGY

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

(2013) G. Zhang et al.   BLOOD

Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis

(2013) Wan-fu Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune modulating peptides for the treatment and suppression of multiple sclerosis

(2012) Ahmed H. Badawi et al.   CLINICAL IMMUNOLOGY

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

(2012) M. W. Ferenczy et al.   CLINICAL MICROBIOLOGY REVIEWS

Biologic Therapies: Lessons from Multiple Sclerosis

(2012) Subrata Ghosh   DIGESTIVE DISEASES

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents

(2012) Yuko Kageyama et al.   HEPATOLOGY

The mRNA expression profile of cytokines connected to the regulation of melanocyte functioning in vitiligo skin biopsy samples and peripheral blood mononuclear cells

(2012) Ene Reimann et al.   HUMAN IMMUNOLOGY

S1PR2 links germinal center confinement and growth regulation

(2012) Jesse A. Green et al.   IMMUNOLOGICAL REVIEWS

Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier

(2012) Brian P. Daniels et al.   JOURNAL OF NEUROSCIENCE METHODS

Turning point: Mark Lawrence

(2012) Alexandra Bell   NATURE

Sphingosine-1-Phosphate Enhances Satellite Cell Activation in Dystrophic Muscles through a S1PR2/STAT3 Signaling Pathway

(2012) Kenneth C. Loh et al.   PLoS One

Sphingosine 1-Phosphate Modulates Antigen Capture by Murine Langerhans Cells via the S1P2 Receptor Subtype

(2012) Lukasz Japtok et al.   PLoS One

Development of oral agent in the treatment of multiple sclerosis: how the first available oral therapy, Fingolimod will change therapeutic paradigm approach

(2012) Claudio Gasperini et al.   Drug Design Development and Therapy

Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis

(2011) Jeffrey A. Cohen et al.   ANNALS OF NEUROLOGY

Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female rats

(2011) Jon Dang et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroprotective effects of estrogens and androgens in CNS inflammation and neurodegeneration

(2011) Rory D. Spence et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Sex differences and genomics in autoimmune diseases

(2011) Shashi Amur et al.   JOURNAL OF AUTOIMMUNITY

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity

(2011) Lillian Cruz-Orengo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of Sphingosine 1-Phosphate Receptor 2 Protects against Renal Ischemia-Reperfusion Injury

(2011) S. Won Park et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages

(2011) T. McQuiston et al.   MICROBIOLOGY-SGM

The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement

(2011) Jesse A Green et al.   NATURE IMMUNOLOGY

Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation

(2011) T. Hla et al.   NEUROLOGY

The Epidemiology of Multiple Sclerosis in Scotland: Inferences from Hospital Admissions

(2011) Adam E. Handel et al.   PLoS One

Regulation of Endothelial Permeability via Paracellular and Transcellular Transport Pathways

(2010) Yulia Komarova et al.   Annual Review of Physiology

Sphingosine-1-Phosphate Receptor-2 Function in Myeloid Cells Regulates Vascular Inflammation and Atherosclerosis

(2010) Athanasia Skoura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Association Analysis of Genes of the IL19 Cluster and Their Receptors in Vitiligo Patients

(2010) Külli Kingo et al.   DERMATOLOGY

Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium

(2010) Weiyong Shen et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Oral fingolimod for relapsing-remitting multiple sclerosis

(2010) Sheila A Doggrell   EXPERT OPINION ON PHARMACOTHERAPY

Fingolimod for the treatment of relapsing multiple sclerosis

(2010) Douglas R Jeffery et al.   Expert Review of Neurotherapeutics

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

(2010) M. G. Lampugnani et al.   JOURNAL OF CELL SCIENCE

Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

(2010) Carole A. Oskeritzian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hormonal influences in multiple sclerosis: New therapeutic benefits for steroids

(2010) Martine El-Etr et al.   MATURITAS

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

CRITICAL VASOSPASM DURING FINGOLIMOD (FTY720) TREATMENT IN A PATIENT WITH MULTIPLE SCLEROSIS

(2010) A. Schwarz et al.   NEUROLOGY

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Claudin-5 as a Novel Estrogen Target in Vascular Endothelium

(2009) Malgorzata Burek et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Integrity Mediated by Vascular Endothelial Cadherin and Regulated by Sphingosine 1-Phosphate and Angiopoietin-1

(2009) Naoki Mochizuki   CIRCULATION JOURNAL

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice

(2009) Eric Camerer et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-1R Signaling within the Central Nervous System Regulates CXCL12 Expression at the Blood-Brain Barrier and Disease Severity during Experimental Autoimmune Encephalomyelitis

(2009) E. E. McCandless et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Y Chromosome Controls the Age-Dependent Experimental Allergic Encephalomyelitis Sexual Dimorphism in SJL/J Mice

(2009) K. M. Spach et al.   JOURNAL OF IMMUNOLOGY

Intercellular Junction Assembly, Dynamics, and Homeostasis

(2009) K. J. Green et al.   Cold Spring Harbor Perspectives in Biology

Pathological Expression of CXCL12 at the Blood-Brain Barrier Correlates with Severity of Multiple Sclerosis

(2008) Erin E. McCandless et al.   AMERICAN JOURNAL OF PATHOLOGY

Association analysis of IL20RA and IL20RB genes in psoriasis

(2008) K Kingo et al.   GENES AND IMMUNITY

A role for sex chromosome complement in the female bias in autoimmune disease

(2008) Deborah L. Smith-Bouvier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis

(2008) E. E. McCandless et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA