CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells

Plasticity in programming of effector and memory CD8+T-cell formation

(2015) Ramon Arens et al.   IMMUNOLOGICAL REVIEWS

TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo

(2013) Q. Zhang et al.   BLOOD

S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma

(2012) Y. Liu et al.   BLOOD

Immunology beats cancer: a blueprint for successful translation

(2012) Drew M Pardoll   NATURE IMMUNOLOGY

Targeting Regulatory T Cells in Cancer

(2011) W. L. Byrne et al.   CANCER RESEARCH

STAT3 Inhibition Is a Therapeutic Strategy for ABC-like Diffuse Large B-Cell Lymphoma

(2011) A. Scuto et al.   CANCER RESEARCH

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras

(2011) Lee Adam Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Progress Toward In Vivo Use of siRNAs-II

(2011) Garrett R Rettig et al.   MOLECULAR THERAPY

Targeting Stat3 in the Myeloid Compartment Drastically Improves the In vivo Antitumor Functions of Adoptively Transferred T Cells

(2010) A. Herrmann et al.   CANCER RESEARCH

Targeting STAT3 in Adoptively Transferred T Cells Promotes Their In Vivo Expansion and Antitumor Effects

(2010) M. Kujawski et al.   CANCER RESEARCH

Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3

(2010) Jason Brayer et al.   IMMUNOLOGY LETTERS

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies

(2009) Karl S. Peggs et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Role of Stat3 in suppressing anti-tumor immunity

(2008) Marcin Kortylewski et al.   CURRENT OPINION IN IMMUNOLOGY

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE