标题
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 124, Issue 1, Pages 353-366
出版商
American Society for Clinical Investigation
发表日期
2013-12-08
DOI
10.1172/jci67871
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- FOXO3A directs a protective autophagy program in haematopoietic stem cells
- (2013) Matthew R. Warr et al. NATURE
- Updates on the biology and management of dyskeratosis congenita and related telomere biology disorders
- (2013) Bari J Ballew et al. Expert Review of Hematology
- Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita
- (2012) F. Beier et al. BLOOD
- TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends
- (2012) Franklin L. Zhong et al. CELL
- Mitochondrial Localization of Telomeric Protein TIN2 Links Telomere Regulation to Metabolic Control
- (2012) Liuh-Yow Chen et al. MOLECULAR CELL
- The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity
- (2012) Jayakrishnan Nandakumar et al. NATURE
- Essential roles for Pot1b in HSC self-renewal and survival
- (2011) Y. Wang et al. BLOOD
- Telomere Protection by TPP1/POT1 Requires Tethering to TIN2
- (2011) Kaori K. Takai et al. MOLECULAR CELL
- Telomere dysfunction induces metabolic and mitochondrial compromise
- (2011) Ergün Sahin et al. NATURE
- Differences in Disease Severity but Similar Telomere Lengths in Genetic Subgroups of Patients with Telomerase and Shelterin Mutations
- (2011) Tom J. Vulliamy et al. PLoS One
- Telomere length measurement can distinguish pathogenic from non-pathogenic variants in the shelterin component, TIN2
- (2010) T Vulliamy et al. CLINICAL GENETICS
- p53 Prevents Entry into Mitosis with Uncapped Telomeres
- (2010) Maria Thanasoula et al. CURRENT BIOLOGY
- TPP1 Is Required for TERT Recruitment, Telomere Elongation during Nuclear Reprogramming, and Normal Skin Development in Mice
- (2010) Agueda M. Tejera et al. DEVELOPMENTAL CELL
- Mitochondria and cell death: outer membrane permeabilization and beyond
- (2010) Stephen W. G. Tait et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A child with severe form of dyskeratosis congenita and TINF2 mutation of shelterin complex
- (2010) Nazan Sarper et al. PEDIATRIC BLOOD & CANCER
- Genetic p53 Deficiency Partially Rescues the Adrenocortical Dysplasia Phenotype at the Expense of Increased Tumorigenesis
- (2009) Tobias Else et al. CANCER CELL
- Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis
- (2009) Christopher N. Vlangos et al. DEVELOPMENTAL BIOLOGY
- Human RAP1 inhibits non-homologous end joining at telomeres
- (2009) Jay Sarthy et al. EMBO JOURNAL
- Dyskeratosis Congenita
- (2009) Sharon A. Savage et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Telomere Protection by TPP1 Is Mediated by POT1a and POT1b
- (2009) T. Kibe et al. MOLECULAR AND CELLULAR BIOLOGY
- Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
- (2009) Michael J. Chen et al. NATURE
- IFNα activates dormant haematopoietic stem cells in vivo
- (2009) Marieke A. G. Essers et al. NATURE
- Telomere Diseases
- (2009) Rodrigo T. Calado et al. NEW ENGLAND JOURNAL OF MEDICINE
- TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita
- (2008) Sharon A. Savage et al. AMERICAN JOURNAL OF HUMAN GENETICS
- How Shelterin Protects Mammalian Telomeres
- (2008) Wilhelm Palm et al. Annual Review of Genetics
- TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes
- (2008) A. J. Walne et al. BLOOD
- Engineered telomere degradation models dyskeratosis congenita
- (2008) D. Hockemeyer et al. GENES & DEVELOPMENT
- Functional Dissection of Human and Mouse POT1 Proteins
- (2008) W. Palm et al. MOLECULAR AND CELLULAR BIOLOGY
- Pot1b Deletion and Telomerase Haploinsufficiency in Mice Initiate an ATR-Dependent DNA Damage Response and Elicit Phenotypes Resembling Dyskeratosis Congenita
- (2008) H. He et al. MOLECULAR AND CELLULAR BIOLOGY
- Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells
- (2008) D. T. Breault et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started