标题
Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 122, Issue 1, Pages 241-252
出版商
American Society for Clinical Investigation
发表日期
2011-12-03
DOI
10.1172/jci58928
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents
- (2011) Jean-Damien Charrier et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting ATR and Chk1 kinases for cancer treatment: A new model for new (and old) drugs
- (2011) Luis I. Toledo et al. Molecular Oncology
- Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR
- (2011) Philip M Reaper et al. Nature Chemical Biology
- A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
- (2011) Luis I Toledo et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells
- (2011) P T Ferrao et al. ONCOGENE
- Chk1 is essential for chemical carcinogen-induced mouse skin tumorigenesis
- (2011) L M Tho et al. ONCOGENE
- Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase
- (2011) M. Kawasumi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
- (2010) O. Gilad et al. CANCER RESEARCH
- Removing all obstacles: A critical role for p53 in promoting tissue renewal
- (2010) David W. Schoppy et al. CELL CYCLE
- Selective activation of p53-mediated tumour suppression in high-grade tumours
- (2010) Melissa R. Junttila et al. NATURE
- Stage-specific sensitivity to p53 restoration during lung cancer progression
- (2010) David M. Feldser et al. NATURE
- Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint
- (2010) Han Liu et al. NATURE
- Death by releasing the breaks: CHK1 inhibitors as cancer therapeutics
- (2010) Cynthia X. Ma et al. TRENDS IN MOLECULAR MEDICINE
- Mouse models of human AML accurately predict chemotherapy response
- (2009) J. Zuber et al. GENES & DEVELOPMENT
- Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis
- (2009) Kevin D. Smith et al. JOURNAL OF CELL BIOLOGY
- Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
- (2009) Yaroslava Ruzankina et al. NATURE GENETICS
- A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
- (2009) Matilde Murga et al. NATURE GENETICS
- Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation
- (2009) K R Greenow et al. ONCOGENE
- Dual inactivation of Hus1 and p53 in the mouse mammary gland results in accumulation of damaged cells and impaired tissue regeneration
- (2009) Stephanie A. Yazinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATR and H2AX Cooperate in Maintaining Genome Stability under Replication Stress
- (2008) Rebecca A. Chanoux et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apoptotic signaling by c-MYC
- (2008) B Hoffman et al. ONCOGENE
- An Oncogene-Induced DNA Damage Model for Cancer Development
- (2008) T. D. Halazonetis et al. SCIENCE
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