SOX2 regulates the hypothalamic-pituitary axis at multiple levels

HESX1- and TCF3-mediated repression of Wnt/ -catenin targets is required for normal development of the anterior forebrain

(2011) C. L. Andoniadou et al.   DEVELOPMENT

Birthdating studies reshape models for pituitary gland cell specification

(2011) Shannon W. Davis et al.   DEVELOPMENTAL BIOLOGY

SOX2 haploinsufficiency is associated with slow progressing hypothalamo-pituitary tumours

(2011) Kyriaki S. Alatzoglou et al.   HUMAN MUTATION

The role of homeodomain transcription factors in heritable pituitary disease

(2011) Kelly L. Prince et al.   Nature Reviews Endocrinology

Increased Wingless (Wnt) signaling in pituitary progenitor/stem cells gives rise to pituitary tumors in mice and humans

(2011) C. Gaston-Massuet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium

(2010) E. S. Tucker et al.   DEVELOPMENT

Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism

(2010) Anna Cariboni et al.   HUMAN MOLECULAR GENETICS

Molecular genetics of the developing neuroendocrine hypothalamus

(2010) Eva Szarek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PROP1 coexists with SOX2 and induces PIT1-commitment cells

(2009) Saishu Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic Regulation of Pituitary Gland Development in Human and Mouse

(2009) Daniel Kelberman et al.   ENDOCRINE REVIEWS

The Notch Target GeneHes1Regulates Cell Cycle Inhibitor Expression in the Developing Pituitary

(2009) Pamela Monahan et al.   ENDOCRINOLOGY

Distinct Developmental Roles of Cell Cycle Inhibitors p57Kip2 and p27Kip1 Distinguish Pituitary Progenitor Cell Cycle Exit from Cell Cycle Reentry of Differentiated Cells

(2009) S. Bilodeau et al.   MOLECULAR AND CELLULAR BIOLOGY

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh

(2009) Rebecca Favaro et al.   NATURE NEUROSCIENCE

Role of Seminiferous Tubular Development in Determining the FSH versus LH Responsiveness to GnRH in Early Sexual Maturation

(2009) Nelly Pitteloud et al.   NEUROENDOCRINOLOGY

Isolated Familial Hypogonadotropic Hypogonadism and aGNRH1Mutation

(2009) Jérôme Bouligand et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants

(2008) M. Cavallaro et al.   DEVELOPMENT

Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development

(2008) Carles Gaston-Massuet et al.   DEVELOPMENTAL BIOLOGY

Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism

(2008) E. Sajedi et al.   Disease Models & Mechanisms

Consequence of the loss of Sox2 in the developing brain of the mouse

(2008) Satoru Miyagi et al.   FEBS LETTERS

SOX2Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development

(2008) Daniel Kelberman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland

(2008) T. Fauquier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

(2008) A. Dabdoub et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of SOX2 in Hypogonadotropic Hypogonadism

(2008) V. Tziaferi et al.   Sexual Development