期刊
JOURNAL OF CLINICAL INVESTIGATION
卷 122, 期 6, 页码 1967-1970出版社
AMER SOC CLINICAL INVESTIGATION INC
DOI: 10.1172/JCI63818
关键词
-
资金
- Canadian Institutes of Health Research Funding Source: Medline
Inflammation plays an essential role in vascular pathologies, including those associated with sepsis and atherosclerosis. Identifying negative regulators of inflammatory signaling pathways may provide novel therapeutic targets for these diseases. In this issue of the JCI, Sun et al. show that in endothelial cells, microRNA-181b (miR-181b) plays a vital role in controlling inflammation by targeting importin-alpha 3, a regulator of NF-kappa B nuclear import. These findings provide compelling evidence that modulation of microRNAs may be a useful therapeutic approach for inflammatory vascular diseases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据