Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice

(2010) C. Tabata et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Two Distinct Regions of Latency-associated Peptide Coordinate Stability of the Latent Transforming Growth Factor-β1 Complex

(2010) Kelly L. Walton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II–infused mice

(2010) Yu Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of Rho-Kinase Inhibition on Pulmonary Hypertension, Lung Growth, and Structure in Neonatal Rats Chronically Exposed to Hypoxia

(2010) Adrian J A Ziino et al.   PEDIATRIC RESEARCH

BIPHASIC EFFECTS OF SELECTIVE INHIBITION OF TRANSFORMING GROWTH FACTOR β1 ACTIVIN RECEPTOR-LIKE KINASE ON LPS-INDUCED LUNG INJURY

(2010) Wei Wei et al.   SHOCK

Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

(2009) Kurt R. Stenmark et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of Epidermal Growth Factor Inhibition in Experimental Pulmonary Hypertension

(2009) Bhola Kumar Dahal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rosiglitazone Attenuates Chronic Hypoxia–Induced Pulmonary Hypertension in a Mouse Model

(2009) Rachel E. Nisbet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension

(2009) Lu Long et al.   CIRCULATION

Growth factors and interleukin-6 across the lung circulation in pulmonary hypertension

(2009) N. Selimovic et al.   EUROPEAN RESPIRATORY JOURNAL

Calpain Expression and Activity during Lens Fiber Cell Differentiation

(2009) Alicia De Maria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

(2009) Paul M. Hassoun et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling

(2009) Ramars Amanchy et al.   Molecular Oncology

Pathology of Pulmonary Arterial Hypertension

(2009) Rubin Tuder   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Activin-Like Kinase 5 (ALK5) Mediates Abnormal Proliferation of Vascular Smooth Muscle Cells from Patients with Familial Pulmonary Arterial Hypertension and Is Involved in the Progression of Experimental Pulmonary Arterial Hypertension Induced by Monocrotaline

(2008) Matthew Thomas et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of the TGF-β/Alk5 Signaling Pathway in Monocrotaline-induced Pulmonary Hypertension

(2008) Ari L. Zaiman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endocytic regulation of TGF-β signaling

(2008) Ye-Guang Chen   CELL RESEARCH

An Ezrin/Calpain/PI3K/AMPK/eNOS s1179 Signaling Cascade Mediating VEGF-Dependent Endothelial Nitric Oxide Production

(2008) Ji-Youn Youn et al.   CIRCULATION RESEARCH

Role of Epidermal Growth Factor Receptor in Ovine Fetal Pulmonary Vascular Remodeling Following Exposure to High Altitude Long-Term Hypoxia

(2008) Lavonne Sheng et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Activation of TGF-β within cultured hepatocytes and in liver injury leads to intracrine signaling with expression of connective tissue growth factor

(2008) Olav A. Gressner et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Molecular pathogenesis of pulmonary arterial hypertension

(2008) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A

(2008) C Bertoli et al.   ONCOGENE