Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

BH3-only Activator Proteins Bid and Bim Are Dispensable for Bak/Bax-dependent Thrombocyte Apoptosis Induced by Bcl-xL Deficiency

(2011) Takahiro Kodama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombocytopenia Exacerbates Cholestasis-Induced Liver Fibrosis in Mice

(2010) Takahiro Kodama et al.   GASTROENTEROLOGY

The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib

(2010) Hayato Hikita et al.   HEPATOLOGY

Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases

(2010) Olav A. Gressner et al.   LIVER INTERNATIONAL

De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures

(2010) A Ernst et al.   ONCOGENE

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

(2010) W. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connective tissue growth factor: Context-dependent functions and mechanisms of regulation

(2009) Iwona Cicha et al.   BIOFACTORS

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

Regulation of chondrocytic phenotype by micro RNA 18a: Involvement ofCcn2/Ctgfas a major target gene

(2009) Toshihiro Ohgawara et al.   FEBS LETTERS

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells

(2009) Hayato Hikita et al.   HEPATOLOGY

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

(2009) Hayato Hikita et al.   HEPATOLOGY

Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes

(2009) ZhenYue Tong et al.   HEPATOLOGY

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo

(2009) Christian Ostrau et al.   RADIOTHERAPY AND ONCOLOGY

Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-β1

(2008) Valérie Haydont et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

(2008) Rudy F. Duisters et al.   CIRCULATION RESEARCH

Expression of p53 protein in liver and sera of patients with liver fibrosis, liver cirrhosis or hepatocellular carcinoma associated with chronic HCV infection

(2008) Abdelfattah M. Attallah et al.   CLINICAL BIOCHEMISTRY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Animal models of NASH: Getting both pathology and metabolic context right

(2008) Claire Z Larter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

(2008) Claudia Mitchell et al.   Nature Protocols