Pain as a channelopathy

Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T

(2010) Brian W. Jarecki et al.   Channels

Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies

(2010) Stephen C. Cannon et al.   JOURNAL OF CLINICAL INVESTIGATION

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents

(2010) Brian W. Jarecki et al.   JOURNAL OF CLINICAL INVESTIGATION

Gain of Function in FHM-1 Cav2.1 Knock-In Mice Is Related to the Shape of the Action Potential

(2010) Carlota González Inchauspe et al.   JOURNAL OF NEUROPHYSIOLOGY

Migraine aura pathophysiology: the role of blood vessels and microembolisation

(2010) Turgay Dalkara et al.   LANCET NEUROLOGY

A neural mechanism for exacerbation of headache by light

(2010) Rodrigo Noseda et al.   NATURE NEUROSCIENCE

A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome

(2010) Barbara Kremeyer et al.   NEURON

Transient receptor potential channelopathies

(2010) Bernd Nilius et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Pain perception is altered by a nucleotide polymorphism in SCN9A

(2010) F. Reimann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

(2009) Michael Costigan et al.   Annual Review of Neuroscience

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Molecular genetics of migraine

(2009) Boukje de Vries et al.   HUMAN GENETICS

TRPC1 and TRPC6 Channels Cooperate with TRPV4 to Mediate Mechanical Hyperalgesia and Nociceptor Sensitization

(2009) N. Alessandri-Haber et al.   JOURNAL OF NEUROSCIENCE

Origin of pain in migraine: evidence for peripheral sensitisation

(2009) Jes Olesen et al.   LANCET NEUROLOGY

Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C

(2009) Michaela Auer-Grumbach et al.   NATURE GENETICS

Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4

(2009) Han-Xiang Deng et al.   NATURE GENETICS

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C

(2009) Guida Landouré et al.   NATURE GENETICS

Elicited repetitive daily blindness: A new phenotype associated with hemiplegic migraine and SCN1A mutations

(2009) K. Vahedi et al.   NEUROLOGY

Enhanced Excitatory Transmission at Cortical Synapses as the Basis for Facilitated Spreading Depression in CaV2.1 Knockin Migraine Mice

(2009) Angelita Tottene et al.   NEURON

A Role of SCN9A in Human Epilepsies, As a Cause of Febrile Seizures and As a Potential Modifier of Dravet Syndrome

(2009) Nanda A. Singh et al.   PLoS Genetics

Genetics of Irritable Bowel Syndrome

(2008) Yuri A. Saito et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy

(2008) Yuri A. Saito et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genetic Calcium Signaling Abnormalities in the Central Nervous System: Seizures, Migraine, and Autism

(2008) J. Jay Gargus   Annals of the New York Academy of Sciences

Progress in Genetic Studies of Pain and Analgesia

(2008) Michael L. LaCroix-Fralish et al.   Annual Review of Pharmacology and Toxicology

First Mutation in the Voltage-Gated Nav1.1 Subunit Gene SCN1A with Co-Occurring Familial Hemiplegic Migraine and Epilepsy

(2008) M-J Castro et al.   CEPHALALGIA

Sensory neuron voltage-gated sodium channels as analgesic drug targets

(2008) Aliakmal Momin et al.   CURRENT OPINION IN NEUROBIOLOGY

Self-Limited Hyperexcitability: Functional Effect of a Familial Hemiplegic Migraine Mutation of the Nav1.1 (SCN1A) Na+ Channel

(2008) S. Cestele et al.   JOURNAL OF NEUROSCIENCE

NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders

(2008) M. Estacion et al.   JOURNAL OF NEUROSCIENCE

Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases

(2008) W. A. Catterall et al.   JOURNAL OF NEUROSCIENCE

Proteomic Profiling of Neuromas Reveals Alterations in Protein Composition and Local Protein Synthesis in Hyper-Excitable Nerves

(2008) Hong-Lei Huang et al.   Molecular Pain

The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain

(2008) B. Abrahamsen et al.   SCIENCE

Neuronal TRP channels: thermometers, pathfinders and life-savers

(2008) Karel Talavera et al.   TRENDS IN NEUROSCIENCES