Article
Gastroenterology & Hepatology
Francesca Ferretti, Federica Branchi, Stefania Orlando, Leda Roncoroni, Giulio Barigelletti, Sabrina Fabiano, Maurizio Vecchi, Roberto Penagini, Luisa Doneda, Luca Elli
Summary: CE and DBE have a high diagnostic yield in identifying and monitoring complicated celiac disease. Patients older than age 50 years with a CD duration shorter than 5 years are more likely to have positive CE results. Some SB lesions are unreachable by upper endoscopy.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Engineering, Biomedical
V. Jahmunah, Joel En Wei Koh, Vidya K. Sudarshan, U. Raghavendra, Anjan Gudigar, Shu Lih Oh, Hui Wen Loh, Oliver Faust, Prabal Datta Barua, Edward J. Ciaccio, U. Rajendra Acharya
Summary: In this study, information extraction methods were used to differentiate Celiac Disease (CD) from non-CD. Statistical and non-linear methods were found to be the most important for information extraction. These tools can reduce variability in clinical workflows, but bias introduced during the design of diagnostic support systems may limit the general validity of the results. Understanding the limitations of information extraction tools can improve the process.
BIOCYBERNETICS AND BIOMEDICAL ENGINEERING
(2023)
Article
Gastroenterology & Hepatology
Friedrich Foerster, Helmut Neumann
Summary: The novel panintestinal capsule endoscopy system shows promising utility in diagnosing patients with celiac disease, as well as the ability to identify colon polyps effectively.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2021)
Article
Medicine, General & Internal
Soo-Young Na, Yun-Jeong Lim
Summary: Capsule endoscopy has proven to be valuable for diagnosing small bowel diseases, with utility in both CD and UC patients. While having a high diagnostic yield, CE is most cost effective as a third diagnostic test and has potential in the utility of CCE for colon diseases.
Review
Pediatrics
Stanley A. Cohen, Salvatore Oliva
Summary: Capsule endoscopy is an important diagnostic tool for both pediatric and adult populations, with a higher diagnostic certainty in evaluating inflammatory bowel disease compared to radiographic studies and surrogate biomarkers. Newer capsule technologies present opportunities for expanding our understanding and practices, but further studies are needed to determine the best uses and candidate selection criteria.
FRONTIERS IN PEDIATRICS
(2021)
Article
Gastroenterology & Hepatology
Rui de Sousa Magalhaes, Catia Arieira, Pedro Boal Carvalho, Bruno Rosa, Maria Joao Moreira, Jose Cotter
Summary: The study validated a new grading scale CC-CLEAR for evaluating colon capsule cleansing, showing excellent inter- and intraobserver agreement.
GASTROINTESTINAL ENDOSCOPY
(2021)
Review
Medicine, General & Internal
Fintan O'Hara, Deirdre McNamara
Summary: Small bowel capsule endoscopy (SBCE) has revolutionized the diagnosis of small bowel pathology by offering a non-invasive and well-tolerated procedure. However, there are still uncertainties in technical aspects, such as incomplete examinations, poor imaging quality, and the risk of capsule retention, which hinders its clinical utility.
Article
Medicine, General & Internal
Writaja Halder, Faidon-Marios Laskaratos, Hanan El-Mileik, Sergio Coda, Stevan Fox, Saswata Banerjee, Owen Epstein
Summary: The COVID-19 pandemic has heavily impacted healthcare services for patients with chronic diseases. This review explores the use of colon capsule endoscopy as a method for assessing and treating inflammatory bowel disease. Despite its limitations, there is increasing evidence to support the use of the second-generation colon capsule.
Review
Pharmacology & Pharmacy
Thomas Bjorsum-Meyer, Anastasios Koulaouzidis, Gunnar Baatrup
Summary: This article reviews the pros and cons of colon capsule endoscopy (CCE) as an alternative to optical colonoscopy (OC), and discusses its application challenges in clinical practice. CCE has the advantages of low risk of complications and can be performed at home, but it also has drawbacks of low completion rates and high re-investigation rates.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE
(2022)
Article
Medicine, General & Internal
Juho Mattila, Teppo Stenholm, Eliisa Loyttyniemi, Jukka Koffert
Summary: The aim of this study was to find predictive markers for clinically significant small bowel Crohn's disease without the need for small bowel capsule endoscopy. The results indicated that fecal calprotectin, serum albumin, and erythrocyte sedimentation rate were significantly different between patients diagnosed with Crohn's disease and those without. A CECDAI score of 3 could serve as a reasonable cutoff value for small bowel Crohn's disease. Follow-up with fecal calprotectin before small bowel capsule endoscopy may be appropriate for patients without endoscopic ileitis, negative imaging results, and fecal calprotectin levels below 50 ug/g.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Computer Science, Artificial Intelligence
Kagan Incetan, Ibrahim Omer Celik, Abdulhamid Obeid, Guliz Irem Gokceler, Kutsev Bengisu Ozyoruk, Yasin Almalioglu, Richard J. Chen, Faisal Mahmood, Hunter Gilbert, Nicholas J. Durr, Mehmet Turan
Summary: Current capsule endoscopes and next-generation robotic capsules are complex cyber-physical platforms that require orchestration of software and hardware functions. Data-driven algorithms and physically-realistic simulations play a key role in the development of these systems.
MEDICAL IMAGE ANALYSIS
(2021)
Review
Gastroenterology & Hepatology
Naoki Hosoe, Kenji J. L. Limpias Kamiya, Yukie Hayashi, Tomohisa Sujino, Haruhiko Ogata, Takanori Kanai
Summary: While the incidence and mortality of colorectal cancer are decreasing in the United States, they are increasing in Japan, highlighting the importance of controlling colorectal cancer in the latter. Colon capsule endoscopy, introduced in 2006, offers a promising alternative to traditional colonoscopy in certain situations, but challenges such as reading burden and lesion oversight still exist. Progress is being made in the development of artificial intelligence for automatic diagnosis of colon capsule endoscopy.
DIGESTIVE ENDOSCOPY
(2021)
Article
Pharmacology & Pharmacy
Qing-Zhou Kong, Cheng Peng, Zhen Li, Bao-Ling Tian, Yue-Yue Li, Fei-Xue Chen, Xiu-Li Zuo, Yan-Qing Li
Summary: This study aimed to explore factors associated with inadequate gastric preparation for magnetically controlled capsule endoscopy (MCE). The use of proton pump inhibitors (PPIs) and premedication time less than 30 minutes were identified as independent risk factors for inadequate gastric preparation. The quality of gastric preparation may be influenced by the type, dose, duration, and discontinuation time of PPIs. Appropriate control of premedication type and time may be crucial for improving overall gastric cleanliness.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Medicine, General & Internal
Trevor Tabone, Anastasios Koulaouzidis, Pierre Ellul
Summary: Colon capsule endoscopy is increasingly recognized as a safe diagnostic tool, especially in the context of reduced endoscopy services. It allows for standardization of reporting and reproducibility through various scores, and can be used to monitor inflammatory bowel disease activity and for colorectal cancer screening.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Tom Kratter, Noam Shapira, Yarden Lev, Or Mauda, Yehonatan Moshkovitz, Roni Shitrit, Shani Konyo, Offir Ukashi, Lior Dar, Oranit Shlomi, Ahmad Albshesh, Shelly Soffer, Eyal Klang, Shomron Ben Horin, Rami Eliakim, Uri Kopylov, Reuma Margalit Yehuda
Summary: The aim of this study was to create an accurate combined algorithm for identifying ulcers on CE images from two different capsules. The separate models for each capsule type achieved excellent accuracy, while the cross-domain model had a wider range of accuracy. The combined model provided high and consistent diagnostic accuracy, making it essential for the development of AI models in clinical practice.