Article
Environmental Sciences
Giehae Choi, Alexander P. Keil, Gro D. Villanger, David B. Richardson, Julie L. Daniels, Kate Hoffman, Amrit K. Sakhi, Cathrine Thomsen, Amy H. Herring, Samantha S. M. Drover, Rachel Nethery, Heidi Aase, Stephanie M. Engel
Summary: This study aimed to investigate the impact of exposure to OPEs and phthalates on maternal thyroid function during pregnancy. The results suggest that certain metabolites are associated with thyroid function biomarkers, but the specific associations may vary depending on the statistical models used.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Multidisciplinary Sciences
Anick Berard, Padma Kaul, Sherif Eltonsy, Brandace Winquist, Dan Chateau, Steven Hawken, Ann Sprague, Mark Walker, Sasha Bernatsky, Michal Abrahamowicz, Cristiano Soares de Moura, Evelyne Vinet, Bruce Carleton, Gillian Hanley, Tim Oberlander, Odile Sheehy, Yessica Haydee Gomez, Jessica Gorgui, Anamaria Savu
Summary: The study shows that pregnant women in Canada commonly use medications, but adverse pregnancy outcomes vary across provinces.
Article
Multidisciplinary Sciences
Ulrike Baum, Sangita Kulathinal, Kari Auranen
Summary: This article discusses the bias in estimating vaccine effectiveness due to non-differential exposure misclassification, pointing out that the bias is quantified by factors such as disease risks, exposure measurement sensitivity and specificity, and vaccination coverage.
Article
Public, Environmental & Occupational Health
Aino K. Rantala, German Tapia, Maria C. Magnus, Lars C. Stene, Jouni J. K. Jaakkola, Ketil Stordal, Oystein Karlstad, Wenche Nystad
Summary: Maternal antibiotic use and infections during pregnancy are associated with an increased risk of offspring asthma. The use of antibiotics during pregnancy is linked to asthma at the age of 7, while maternal infections during pregnancy are associated with asthma at both 7 and 13 years old. However, the effect of antibiotics may reflect a shared underlying susceptibility rather than a direct cause.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Ellen O. Carlsen, Quaker Harmon, Maria C. Magnus, Helle M. Meltzer, Iris Erlund, Lars C. Stene, Siri E. Haberg, Allen J. Wilcox
Summary: This study found that among women without a history of diabetes, higher HbA1c levels at 18 weeks of pregnancy were associated with important perinatal outcomes, including birth weight, large-for-gestational age, preterm delivery, and preeclampsia.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Maria C. Magnus, Abigail Fraser, Janet W. Rich-Edwards, Per Magnus, Deborah A. Lawlor, Siri E. Haberg
Summary: The study found that both women and men with prolonged time-to-pregnancy have a slightly increased risk of cardiovascular disease. Further research is needed to investigate the clinical significance of this phenomenon and the underlying causes of the increased risk of CVD associated with prolonged TTP.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Hematology
Kueiyu Joshua Lin, Sebastian Schneeweiss, Ajinkya Pawar, Daniel E. Singer, Jun Liu, Joshua J. Gagne
Summary: Warfarin remains widely used as a comparator in studies, with longer prescriptions resulting in dosing adjustments. Defining warfarin discontinuation using short gaps may lead to misclassification, but incorporating intervening INR codes can improve accuracy.
THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Substance Abuse
Alexander Testa, Chantal Fahmy, Dylan B. Jackson
Summary: This study reveals that women with exposure to the correctional system in the year before giving birth have higher odds of using prescription opioids during pregnancy, and are also more likely to engage in illicit opioid use.
DRUG AND ALCOHOL DEPENDENCE
(2022)
Article
Public, Environmental & Occupational Health
Buket Ozturk Esen, Vera Ehrenstein, Mette Norgaard, Henrik Toft Sorensen, Lars Pedersen
Summary: By incorporating information on repeatedly redeemed prescriptions and redemptions of drug classes commonly used in pregnancy, this study aimed to reduce bias from exposure misclassification in assessing the effect of prenatal antidepressant-ADHDrelationship. The results did not support the hypothesis that prenatal antidepressant exposure increases the risk of ADHD.
Article
Public, Environmental & Occupational Health
Maria C. Magnus, Alexandra Havdahl, Allen J. Wilcox, Alice Goisis
Summary: Parental time-to-pregnancy is modestly but robustly associated with neurodevelopmental delays and difficulties in offspring, with no additional impact of assisted reproductive technologies.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Psychology, Clinical
Hannah M. Sallis, Jazz Croft, Alexandra Havdahl, Hannah J. Jones, Erin C. Dunn, George Davey Smith, Stanley Zammit, Marcus R. Munafo
Summary: The study found a positive association between schizophrenia polygenic scores and childhood trauma, with consistent results across the ALSPAC and MoBa cohorts. Additionally, genetic liability for a range of psychiatric traits was also associated with greater trauma exposure in ALSPAC, suggesting that youth at higher genetic risk may need more resources and support to ensure a healthy environment for growth.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychology, Clinical
D. Shmulewitz, M. Stohl, E. Greenstein, S. Roncone, C. Walsh, E. Aharonovich, M. M. Wall, D. S. Hasin
Summary: The validity of the DSM-5 substance use disorder (SUD) diagnosis and craving criterion has been systematically investigated across various substances. Craving was found to be associated with baseline validators and predicted subsequent substance use. Including craving improves the validity of DSM-5 SUD diagnoses.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Dogukan Koc, Henning Tiemeier, Bruno H. Stricker, Ryan L. Muetzel, Manon Hillegers, Hanan El Marroun
Summary: This study aims to investigate the association between intrauterine SSRI exposure and maternal depressive symptoms and structural brain development in offspring from mid-childhood to early puberty.
Article
Sport Sciences
Silje Malen Andreassen, Ulf Ekelund, Guro Pauck Bernhardsen
Summary: The study found that maternal exercise level during pregnancy does not seem to be associated with the child's BMI or odds of being overweight or obese in childhood, and the child's physical activity level also does not appear to affect this association.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Pharmacology & Pharmacy
Annalisa Biffi, Federico Rea, Anna Locatelli, Irene Cetin, Amelia Filippelli, Giovanni Corrao
Summary: This study conducted a meta-analysis to illustrate how differential exposure and outcome misclassifications may lead to uncertain conclusions. The results showed that observational investigations and meta-analyses of observational studies need cautious interpretations due to their susceptibility to various sources of bias.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Obstetrics & Gynecology
A. Lupattelli, M. Mahic, M. Handal, E. Ystrom, T. Reichborn-Kjennerud, H. Nordeng
Summary: Children exposed to SSRI/SNRI treatment during pregnancy do not have significantly higher risk of ADHD compared to those who were untreated or discontinued treatment, but there is an elevated risk at 7-9 years old. Maternal depression/anxiety before pregnancy is independently associated with child ADHD.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Medicine, General & Internal
Lars T. Fadnes, Christer Frode Aas, Jorn Henrik Vold, Rafael Alexander Leiva, Christian Ohldieck, Fatemeh Chalabianloo, Svetlana Skurtveit, Ole Jorgen Lygren, Olav Dalgard, Peter Vickerman, Havard Midgard, Else-Marie Loberg, Kjell Arne Johansson
Summary: This study found that integrated treatment for chronic HCV infection among people who inject drugs was more effective in terms of time-to-treatment initiation and achieving sustained virologic response compared to standard treatment. It also showed comparable SVR rates among those who initiated treatment. Scaling up integrated treatment models could be crucial in the elimination of HCV.
Article
Health Care Sciences & Services
Anne Bukten, Nicoline Toresen Lokdam, Ingeborg Skjaervo, Thomas Ugelvik, Svetlana Skurtveit, Roman Gabrhelik, Torbjorn Skardhamar, Ingunn Olea Lund, Ingrid Amalia Havnes, Eline Borger Rognli, Zheng Chang, Seena Fazel, Christine Friestad, Morten Hesse, Johan Lothe, Gerhard Ploeg, Anja J. E. Dirkzwager, Thomas Clausen, Christian Tjagvad, Marianne Riksheim Stavseth
Summary: The PriSUD-Nordic project aims to investigate the epidemiology and lived experiences of people with substance use disorders in the Nordic prison population, with the goal of contributing to better mental and physical health, improved quality of life, and increased life expectancies for this population.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Substance Abuse
Jasmina Burdzovic Andreas, Fartein Ask Torvik, Eivind Ystrom, Svetlana Skurtveit, Marte Handal, Priscilla Martinez, Anne-Marie Laslett, Ingunn Olea Lund
Summary: This study examined the risk of developing future alcohol use disorder (AUD) among offspring from families with different combinations of parental risk factors. The results showed that offspring from families characterized by weekly binge drinking, low education, and poor mental health in parents were more likely to develop AUD, even after adjusting for covariates. This suggests that parental drinking patterns, along with additional risk factors like mental health and education, can significantly impact the risk of AUD in offspring.
PSYCHOLOGY OF ADDICTIVE BEHAVIORS
(2022)
Article
Pharmacology & Pharmacy
Mikkel Hojlund, Larus S. Gudmundsson, Jacob H. Andersen, Leena K. Saastamoinen, Helga Zoega, Svetlana O. Skurtveit, Jonas W. Wastesson, Jesper Hallas, Anton Pottegard
Summary: The use of benzodiazepines and related drugs has decreased in the Nordic countries from 2004 to 2020, with significant differences between countries. Despite warnings, benzodiazepines are still commonly used in the older population.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2023)
Article
Psychology, Developmental
Helle Stangeland, Marte Handal, Svetlana Ondrasova Skurtveit, Helene Flood Aakvaag, Grete Dyb, Tore Wentzel-Larsen, Monica Baumann-Larsen, John Anker Zwart, Kjersti Storheim, Synne Oien Stensland
Summary: This study investigated the trends in prescription drug use among children, adolescents, and young adults over the past 15 years. The study found that the use of prescription drugs was low in children and adolescents, but increased with age in adolescents and young adults, particularly for analgesics and drugs with higher potential for misuse. Additionally, females overall used more prescription drugs than their male peers.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Substance Abuse
Svetlana Skurtveit, Ingvild Odsbu, Linn Gjersing, Marte Handal, Torgeir Gilje Lid, Thomas Clausen, Aleksi Hamina
Summary: This study investigated the differences in characteristics between individuals who died from pharmaceutical opioid (PO) overdoses and those who died from other types of overdoses. The findings revealed that individuals who died from PO overdoses were typically older, more often women, had a higher prevalence of chronic pain, and used higher doses of prescription opioids compared to those who died from other types of overdoses. These differences highlight the need for tailored prevention strategies.
EUROPEAN ADDICTION RESEARCH
(2022)
Article
Clinical Neurology
Mikael Tiger, Rikke Wesselhoeft, Par Karlsson, Marte Handal, Mette Bliddal, Carolyn E. Cesta, Svetlana Skurtveit, Johan Reutfors
Summary: The study found that there was an increase in the utilization of antidepressants, anxiolytics, and hypnotics in Denmark, Norway, and Sweden during the COVID-19 pandemic in 2020. The utilization of antidepressants increased between 13.5% and 31.3% in Denmark and decreased by 16.7% in Swedish youths. There was a general increase in the utilization of other anxiolytics and hypnotics in all countries at the end of 2020. These findings may indicate medication stockpiling and an increase in symptoms of depression, anxiety, and sleep disturbances.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Substance Abuse
Roman Gabrhelik, Svetlana Skurtveit, Blanka Nechanska, Viktor Mravcik, Marte Handal
Summary: This study compares the morbidity rates of children with prenatal methamphetamine (MA) and opioid exposure to those without exposure. The results show that children prenatally exposed to MA and opioids have higher hospitalization rates, diagnosis rates, and longer hospital stays compared to non-exposed children. They also have an increased risk of infectious and parasitic diseases and injuries.
EUROPEAN ADDICTION RESEARCH
(2023)
Article
Substance Abuse
Gabriela Rolova, Desiree Eide, Roman Gabrhelik, Ingvild Odsbu, Thomas Clausen, Svetlana Skurtveit
Summary: This study examines the physical morbidity in two national cohorts of opioid agonist treatment (OAT) patients, focusing on gender differences. Women in OAT have a significantly higher prevalence of physical diseases, especially genitourinary diseases and neoplasms. Injuries/external causes and infectious/parasitic diseases are common in both women and men, with viral hepatitis accounting for over half of infectious morbidity in both cohorts.
SUBSTANCE ABUSE TREATMENT PREVENTION AND POLICY
(2023)
Article
Substance Abuse
Desiree Eide, Svetlana Skurtveit, Thomas Clausen, Morten Hesse, Viktor Mravcik, Blanka Nechanska, Gabriela Rolova, Birgitte Thylstrup, Christian Tjagvad, Abdu Kedir Seid, Ingvild Odsbu, Roman Gabrhelik
Summary: This study aimed to describe non-overdose causes of death among opioid maintenance treatment (OMT) patients in Czechia, Denmark, and Norway, and explore the associations with age and gender. The leading non-overdose causes of death varied across the cohorts, with accidents in Czechia and Denmark, and neoplasms in Norway. Cardiovascular deaths were highest in Czechia, particularly among women in OMT. These findings suggest the importance of screening and preventive health initiatives tailored to the demographic characteristics of OMT patients in different settings.
EUROPEAN ADDICTION RESEARCH
(2023)
