Article
Endocrinology & Metabolism
Julie Abildgaard, Thorkil Ploug, Anette Tonnes Pedersen, Pia Eiken, Bente Klarlund Pedersen, Jens Juul Holst, Bolette Hartmann, Birgitte Lindegaard
Summary: Despite higher fasting levels, postmenopausal women exhibit comparable postprandial suppression of bone turnover markers to premenopausal women. None of the postprandial gut hormone increases predict postprandial bone turnover suppression.
Article
Nutrition & Dietetics
Christa Ellis, Herculina S. Kruger, Michelle Viljoen, Joel A. Dave, Marlena C. Kruger
Summary: The study found that changes in bone mineral density and bone resorption markers over two years were minimal in black postmenopausal women living with HIV. Despite a decrease in serum vitamin D, there were small or no changes in BMD and CTx over the 2-year period.
Article
Medicine, General & Internal
Izabela Michalus, Anna Lupinska, Izabela Woch, Katarzyna Wieczorek-Szukala, Danuta Chlebna-Soko, Andrzej Lewinski
Summary: This retrospective study explored the bone turnover and bone mass disorders in children with hypophosphatemic rickets. The results showed that bone metabolism disturbances and worse bone quality were found in these patients. It is crucial to monitor the progress and treatment effects by determining bone turnover markers, dual-energy X-ray absorptiometry findings, and indices of quantitative ultrasound examination.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Wei Wang, Rong Huang, Ping Tai Tang, Mei Tu, Xiu Li Guo
Summary: This study found that perirenal fat thickness is significantly associated with bone turnover markers, bone mineral density, and osteoporosis, suggesting that perirenal fat may play an important role in bone metabolism.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Ran Li, Xiaoyi Zhu, Mengxi Zhang, Guannan Zong, Keqin Zhang
Summary: The study aimed to investigate the serum periostin levels in Chinese postmenopausal women with different bone mass and its correlations with traditional bone turnover markers and bone mineral densities at different sites. The results showed no significant difference in serum periostin levels among the groups of women with normal bone mass, osteopenia, and osteoporosis. Additionally, the study found that serum P1NP and OC levels may be better predictors of osteoporosis in Chinese postmenopausal women than serum periostin.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Review
Endocrinology & Metabolism
Mingwei Hu, Yifan Zhang, Jianjun Guo, Cuicui Guo, Xue Yang, Xue Ma, Hao Xu, Shuai Xiang
Summary: This study evaluated the changes in bone mineral density and bone turnover markers after denosumab and romosozumab therapies in patients with osteoporosis. The results showed that the romosozumab group exhibited greater changes in lumbar BMD and bone turnover markers at 3 months of treatment, while changes in BMD of total hip and femoral neck were relatively delayed. From 6 to 12 months of treatment, romosozumab showed greater changes in bone mineral density and markers of bone turnover.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Environmental Sciences
Wieslaw Kanadys, Agnieszka Baranska, Agata Blaszczuk, Malgorzata Polz-Dacewicz, Bartlomiej Drop, Maria Malm, Krzysztof Kanecki
Summary: This systematic review and meta-analysis study suggests that intake of soy isoflavones may lead to an increase in bone formation markers and a decrease in bone resorption markers. However, these trends were not statistically significant. Further extensive multi-center research is needed to confirm the potential beneficial effects of soy isoflavones on bone health.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Endocrinology & Metabolism
E. Michael Lewiecki, Edward Czerwinski, Chris Recknor, Anna Strzelecka, Guillermo Valenzuela, Mary Lawrence, Stuart Silverman, Jose Cardona, Susan M. Nattrass, Neil Binkley, Miriam Annett, Leny Pearman, Bruce Mitlak
Summary: This study evaluated the safety and efficacy of the abaloparatide microstructured transdermal system (abaloparatide-sMTS) as an alternative to subcutaneous injection. The results showed that the abaloparatide-sMTS was not noninferior to the subcutaneous injection in terms of lumbar spine bone density at 12 months, but both treatments significantly increased lumbar spine and total hip bone density.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Review
Nutrition & Dietetics
Khemayanto Hidayat, Jing-Si Chen, Tian-Ci Wang, Yu-Jie Liu, Yu-Jie Shi, Hong-Wen Su, Biao Liu, Li-Qiang Qin
Summary: This meta-analysis study suggests that milk supplementation can have a positive impact on hip and lumbar spine bone density, as well as reducing bone turnover markers and parathyroid hormone concentrations, potentially preventing bone loss.
ADVANCES IN NUTRITION
(2022)
Review
Nutrition & Dietetics
Minkyung Je, Kyeonghoon Kang, Jun-Il Yoo, Yoona Kim
Summary: This review aims to investigate the effects of macronutrients on bone health in elderly people based on human studies. The results suggest that carbohydrate intake has limited effects on bone fracture but further research is needed on its effects on bone mineral density and bone turnover markers. Additionally, inconsistent results were found regarding the beneficial effects of animal, vegetable, soy, or milk proteins on bone health. Further studies are required to establish a clear association between macronutrients and bone health in elderly people.
Article
Endocrinology & Metabolism
Yang Xu, Li Shen, Lianyong Liu, Zhenlin Zhang, Weiwei Hu
Summary: This study investigated the profile of serum undercarboxylated osteocalcin (ucOC) levels and their associations with bone mineral density (BMD), bone turnover markers (BTMs), and prevalence of osteopenia and osteoporosis in the Chinese population. The results showed that ucOC levels were higher in men than women and decreased with age until the age of 50, after which they increased. Higher ucOC levels were correlated with lower BMD values and higher levels of BTMs in both men and women. Furthermore, an increase in ucOC levels was associated with an increased risk of osteopenia and osteoporosis in both genders.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Wei Wang, Zhe Yuan Chen, Fen Yan Lv, Mei Tu, Xiu Li Guo
Summary: This study evaluates the correlation of serum HDL-c and apolipoprotein A1 (APOA1) with bone metabolism in Chinese postmenopausal women with type 2 diabetes mellitus (T2DM). The results show that APOA1 is more strongly associated with bone metabolism compared to HDL-c.
FRONTIERS IN MEDICINE
(2023)
Article
Nutrition & Dietetics
Juan J. Lopez-Gomez, Jose L. Perez-Castrillon, Isabel Garcia de Santos, Maria Perez-Alonso, Olatz Izaola-Jauregui, David Primo-Martin, Daniel A. De Luis-Roman
Summary: This study examined the differences in bone metabolism between postmenopausal women with and without obesity, and compared the risk of fracture at five years between these groups.
Article
Endocrinology & Metabolism
Shannon Clare, Alexander Dash, Yi Liu, Jonathan Harrison, Katelyn Vlastaris, Seth Waldman, Robert Griffin, Paul Cooke, Vijay Vad, Ellen Casey, Richard S. Bockman, Joseph Lane, Donald McMahon, Emily M. Stein
Summary: This study investigated the acute changes in bone turnover following epidural steroid injections (ESIs) in postmenopausal women. Results showed a significant decrease in bone formation markers one week after ESI, which lasted for at least 12 weeks. Further investigation into the long-term skeletal consequences of these injections is warranted, considering the large population of older adults who receive ESIs.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Xiaowen Zhang, Suhas Krishnamoorthy, Casey Tze-Lam Tang, Warrington Wen-Qiang Hsu, Gloria Hoi-Yee Li, Chor-Wing Sing, Kathryn Choon-Beng Tan, Bernard Man-Yung Cheung, Ian Chi-Kei Wong, Annie Wai-Chee Kung, Ching-Lung Cheung
Summary: This study investigated the association between bone health and incident type-2 diabetes mellitus (T2DM). The results showed that higher bone density is associated with an increased risk of T2DM.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Michelle L. O'Donoghue, Eugene Braunwald, Harvey D. White, Patrick Serruys, Ph. Gabriel Steg, Judith Hochman, Aldo P. Maggioni, Christoph Bode, Douglas Weaver, Joel L. Johnson, Greg Cicconetti, Mary Ann Lukas, Elizabeth Tarka, Christopher P. Cannon
AMERICAN HEART JOURNAL
(2011)
Article
Endocrinology & Metabolism
Lorraine A. Fitzpatrick, Margaret Wooddell, Christine E. Dabrowski, Gregory Cicconetti, David N. Gordon
Article
Endocrinology & Metabolism
Lorraine A. Fitzpatrick, Christine E. Dabrowski, Gregory Cicconetti, David N. Gordon, Thomas Fuerst, Klaus Engelke, Harry K. Genant
JOURNAL OF BONE AND MINERAL RESEARCH
(2012)
Article
Mathematical & Computational Biology
Cristiana Mayer, Inna Perevozskaya, Sergei Leonov, Vladimir Dragalin, Yili Pritchett, Alun Bedding, Alan Hartford, Parvin Fardipour, Greg Cicconetti
STATISTICS IN BIOPHARMACEUTICAL RESEARCH
(2019)
Meeting Abstract
Ophthalmology
Rachel Williams, Shawn Patrick Shearn, Michael Dowd, Greg Cicconetti, Lars Wallentin, Harvey White, Salim Janmohamed, John I. Wurzelmann, Megan M. McLaughlin
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2015)
Meeting Abstract
Endocrinology & Metabolism
L. A. Fitzpatrick, C. E. Dabrowski, G. Cicconetti, D. Gordon, T. Fuerst, K. Engelke, H. Genant
OSTEOPOROSIS INTERNATIONAL
(2010)
Article
Geriatrics & Gerontology
Sam Bub, Josef Brinckmann, Greg Cicconetti, Barbara Valentine
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2006)
Meeting Abstract
Endocrinology & Metabolism
L. A. Fitzpatrick, C. E. Dabrowski, G. Cicconetti, S. Papapoulos, H. G. Bone, J. P. Bilezikian
OSTEOPOROSIS INTERNATIONAL
(2010)
Meeting Abstract
Endocrinology & Metabolism
L. A. Fitzpatrick, C. Dabrowski, G. Cicconetti, T. Fuerst, K. Engelke, H. K. Genant
OSTEOPOROSIS INTERNATIONAL
(2010)