Article
Clinical Neurology
Kathleen G. Dobson, Simone N. Vigod, Cameron Mustard, Peter M. Smith
Summary: Experiencing a major depressive episode (MDE) is associated with consistently lower earnings for ten years post-MDE, with similar immediate impact on earnings for men and women. Effective clinical treatment and labor policy during the critical period surrounding an MDE may help mitigate longstanding earnings loss.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Editorial Material
Endocrinology & Metabolism
Anju E. Joham, Helena J. Teede
Summary: A new paper investigates the genetic risk factors for PCOS and non-reproductive PCOS phenotypes, concluding that PCOS is a metabolic disorder and that ovarian function is not necessary for its cardiometabolic features. The study also highlights the implications of PCOS for both men and women.
NATURE REVIEWS ENDOCRINOLOGY
(2022)
Article
Health Care Sciences & Services
Rui Yang, Qin Li, Zehong Zhou, Weiping Qian, Jian Zhang, Ze Wu, Lei Jin, Xueqing Wu, Cuilian Zhang, Beihong Zheng, Jichun Tan, Guimin Hao, Shangwei Li, Tian Tian, Yongxiu Hao, Danni Zheng, Yuanyuan Wang, Robert J. Norman, Rong Li, Ping Liu, Jie Qiao
Summary: The prevalence of polycystic ovary syndrome (PCOS) has significantly increased in Chinese women over the past 10 years, with the current patients exhibiting more severe symptoms possibly related to the higher prevalence of obesity, hyperandrogenism, and infertility. This study highlights PCOS as a significant public health problem in reproductive-aged women in China.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2022)
Article
Sport Sciences
Stephen W. Farrell, David Leonard, Carolyn E. Barlow, Benjamin L. Willis, Andjelka Pavlovic, Laura F. Defina, William L. Haskell
Summary: This study found strong individual and joint associations between low cardiorespiratory fitness, vitamin D deficiency, and metabolic syndrome among U.S. adult men. Maintaining proper levels of fitness and vitamin D can help reduce the risk of metabolic syndrome. Prospective studies are needed to further evaluate these joint associations with mortality outcomes.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2021)
Article
Genetics & Heredity
Eric G. R. Kim, David C. Kaelber
Summary: This study analyzes the prevalence and screening rates of obesity and metabolic syndrome among adult and pediatric patients. The results indicate that obesity is underdiagnosed and obesity related conditions are underscreened in both pediatric and adult populations. The study also suggests a potential underdiagnosis of metabolic syndrome among patients in the United States.
FRONTIERS IN GENETICS
(2022)
Article
Psychiatry
Feyissa Challa, Tigist Getahun, Meron Sileshi, Zeleke Geto, Teshome S. Kelkile, Sintayehu Gurmessa, Girmay Medhin, Miraf Mesfin, Melkam Alemayehu, Tigist Shumet, Anwar Mulugeta, Desalegn Bekele, Christina P. C. Borba, Claire E. Oppenheim, David C. Henderson, Abebaw Fekadu, Anna Carobene, Solomon Teferra
Summary: The study investigated the prevalence of MetS among patients with schizophrenia in Ethiopia, finding an overall prevalence of 21.5%. Low HDL-cholesterol was the most common metabolic disorder component. Multivariate analysis showed that PANSS scores were associated factors with MetS.
Article
Nutrition & Dietetics
Young-Ae Cho, Jeong-Hwa Choi
Summary: The study investigated the association between carbohydrate intake and metabolic syndrome in Korean women, finding that high carbohydrate intake is associated with an increased risk of metabolic syndrome, particularly abdominal obesity.
Article
Pediatrics
Osama E. Amer, Shaun Sabico, Malak N. K. Khattak, Abdullah M. Alnaami, Naji J. Aljohani, Hanan Alfawaz, Abdulaziz AlHameidi, Nasser M. Al-Daghri
Summary: The study revealed a significant increase in the prevalence of MetS among Arab children and adolescents over a short period of time, with a more evident rise in boys. Early intervention is crucial to curb this trend.
Article
Endocrinology & Metabolism
Anupama Bahadur, Rajlaxmi Mundhra, Jyotshna Kashibhatla, Rashmi Rajput, Neha Verma, Mumta Kumawat
Summary: The study found that PCOS patients with phenotype A have a higher risk profile for MetS, while the overall prevalence of MetS was relatively low. Therefore, it is recommended that all PCOS patients undergo metabolic risk factor screening at a young age.
GYNECOLOGICAL ENDOCRINOLOGY
(2021)
Article
Medicine, General & Internal
Jiaqi Huang, Bin Zhao, Stephanie J. Weinstein, Demetrius Albanes, Alison M. Mondul
Summary: This study conducted comprehensive metabolomic analyses of prostate cancer patients' serum to examine their survival rates. The results showed that certain metabolites were positively associated with prostate cancer-specific mortality risk, while others were negatively associated. Participants with higher metabolic scores had an elevated risk of prostate cancer-specific mortality in a separate dataset.
Article
Environmental Sciences
Yu Zhu, Mingkun Tong, Yingying Wang, Yuchen Liu, Bo Wang, Wanshui Yang, Yi Ning
Summary: This nationwide study in China reveals that thyroid nodules (TNs) are common health problems, and an increased concentration of iodine in drinking water is associated with a higher prevalence of TNs.
ENVIRONMENTAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Fan Yao, Yacong Bo, Liyun Zhao, Yaru Li, Lahong Ju, Hongyun Fang, Wei Piao, Dongmei Yu, Xiangqian Lao
Summary: The prevalence of MetS among Chinese residents aged 20 years or older is increasing, particularly among women, individuals aged 45 years or older, and urban residents. Preventive efforts like quitting smoking and engaging in physical activity are recommended to reduce the risk of MetS.
Article
Medicine, General & Internal
Maria Danielsson, Tarja Tanner, Pertti Patinen, Dowen Birkhed, Vuokko Anttonen, Anelma Lammi, Simo Siitonen, Jukka Ollgren, Liisa Pylkkanen, Tuula Vasankari
Summary: The study revealed that Snus use is very common among young Finnish men, with daily users starting at an earlier age, having a longer duration of use, and higher daily exposure time compared to occasional users. Respondents with a higher education level had significantly less daily total exposure time. Perceptions of Snus as a harmful substance resulted in a significantly lower duration of exposure.
Article
Multidisciplinary Sciences
Isis Gabrielli Gomes Xavier, Marcelo Carvalho Vieira, Luiz Fernando Rodrigues Junior, Gilberto Marcelo Sperandio da Silva, Paula Simplicio da Silva, Marcelo Teixeira de Holanda, Erica Rodrigues Maciel, Fernanda Martins Carneiro, Flavia Mazzoli-Rocha, Luiz Henrique Conde Sangenis, Fernanda de Souza Nogueira Sardinha Mendes, Alejandro Marcel Hasslocher-Moreno, Andrea Silvestre de Sousa, Andrea Rodrigues da Costa, Roberto Magalhaes Saraiva, Pedro Emmanuel Alvarenga Americano do Brasil, Mauro Felippe Felix Mediano
Summary: The study identified a high prevalence of MetS in Brazilian chronic Chagas disease patients, with age, education levels, and cardiac form with heart failure being independently associated factors.
Article
Medicine, General & Internal
Rebecka Papaioannu Borjesson, Laura Galli, Camilla Muccini, Andrea Poli, Tommaso Clemente, Martina Bottanelli, Nicola Gianotti, Silvia Nozza, Antonella Castagna, Vincenzo Spagnuolo
Summary: This study analyzed the impact of the COVID-19 pandemic on the prevalence and incidence of metabolic syndrome in people living with HIV. The results showed an increase in both the prevalence and incidence of metabolic syndrome during the pandemic period.
FRONTIERS IN MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jenni Lehtisalo, Minna Rusanen, Alina Solomon, Riitta Antikainen, Tiina Laatikainen, Markku Peltonen, Timo Strandberg, Jaakko Tuomilehto, Hilkka Soininen, Miia Kivipelto, Tiia Ngandu
Summary: A two-year multi-domain lifestyle intervention among older adults was effective in preventing cerebrovascular events and total cardiovascular disease (CVD) events, particularly among those with a history of CVD.
EUROPEAN HEART JOURNAL
(2022)
Article
Environmental Sciences
Senlin Chen, Baofu Wang, Stacy Imagbe, Xiangli Gu, Jared Androzzi, Yang Liu, Sami R. Yli-Piipari, Gang Hu, Amanda E. Staiano
Summary: The study examines the impact of the COVID-19 pandemic on adolescents' physical activity, sedentary behaviors, health-related fitness, and knowledge understanding. Findings show a decrease in out-of-school physical activity but an increase in physical activity at school during the pandemic. Sedentary behaviors decrease after the pandemic, and health-related fitness improves. The patterns of change in behaviors and knowledge understanding vary by grade and gender.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
George Moschonis, George Siopis, Costas Anastasiou, Violeta Iotova, Tanya Stefanova, Roumyana Dimova, Imre Rurik, Anette Si Rado, Greet Cardon, Marieke De Craemer, Jaana Lindstrom, Luis A. Moreno, Pilar De Miguel-Etayo, Konstantinos Makrilakis, Stavros Liatis, Yannis Manios
Summary: The Feel4Diabetes study recruited 12,193 children and their parents from six European countries to investigate the prevalence of childhood obesity and its association with socio-demographic characteristics and parental obesity status. The study found that living in low income or economically crisis countries, having a father with less education, and having one or both parents who were obese were associated with a higher likelihood of childhood obesity. These findings suggest the importance of targeting the whole family and considering socioeconomic factors in childhood obesity prevention programs.
Article
Medicine, General & Internal
Elisa Neuvonen, Jenni Lehtisalo, Tiia Ngandu, Esko Levaelahti, Riitta Antikainen, Tuomo Hanninen, Tiina Laatikainen, Jaana Lindstrom, Teemu Paajanen, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto, Alina Solomon
Summary: Depressive symptoms may affect improvement in cognitive abilities, with clinically significant symptoms potentially impacting the effectiveness of interventions, warranting further attention in dementia prevention strategies.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Kristjan Karason, Nicolas Girerd, Johanna Andersson-Asssarsson, Kevin Duarte, Magdalena Taube, Per-Arne Svensson, Anne-Cecile Huby, Markku Peltonen, Lena M. Carlsson, Faiez Zannad
Summary: This study investigated the underlying mechanisms of obesity-related heart failure (HF) by analyzing 182 plasma proteins related to cardiovascular disease. The results showed that obesity is associated with inflammation, matrix remodeling, cardiometabolic hormones, and hemostasis, and identified three protein biomarkers that can predict HF with a specific association to obesity.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Article
Environmental Sciences
Mika Venojarvi, Jaana Lindstrom, Sirkka Aunola, Pirjo Nuutila, Mustafa Atalay
Summary: This study aimed to investigate the effects of long-term exercise and dietary intervention on glucose metabolism in middle-aged obese individuals with impaired glucose tolerance. The intervention resulted in decreased leptin levels, increased adiponectin levels, improved insulin sensitivity and maximal oxygen uptake in responders, but did not affect glucose transporter gene expression.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Economics
Yixue Shao, Charles Stoecker, Dongzhe Hong, Elizabeth Nauman, Vivian Fonseca, Gang Hu, Alessandra N. Bazzano, Edmond K. Kabagambe, Lizheng Shi
Summary: This study evaluated the impact of reimbursement for non-face-to-face chronic care management on healthcare utilization among Medicare beneficiaries with type 2 diabetes in Louisiana. The results showed that receiving non-face-to-face chronic care management was associated with increased outpatient visits and decreased inpatient admissions and emergency department visits. In the future, the cost savings of non-face-to-face chronic care management in diabetes management could be further explored.
Article
Endocrinology & Metabolism
Li Ding, Yuxin Fan, Jingting Qiao, Jing He, Ruodan Wang, Qing He, Jingqiu Cui, Zhongshu Ma, Fangqiu Zheng, Hua Gao, Chenlin Dai, Hongyan Wei, Jun Li, Yuming Cao, Gang Hu, Ming Liu
Summary: The distribution of lean mass is associated with the risk of all-cause mortality in patients with type 2 diabetes. A higher android-to-gynoid lean mass ratio is significantly associated with increased risk of all-cause mortality.
PRIMARY CARE DIABETES
(2022)
Editorial Material
Medicine, General & Internal
Gang Hu
CHINESE MEDICAL JOURNAL
(2022)
Article
Endocrinology & Metabolism
Gang Hu, Jonathan Ding, Donna H. Ryan
Summary: This study analyzed the trends in obesity prevalence and control of cardiometabolic risk factors among people with diabetes from 1999 to 2020. The results showed that the prevalence of obesity increased over time, while the percentage of people with glycemic control decreased. However, there was an improvement in blood pressure control and lipid control. Participants with obesity had worse glycemic control and lipid control compared to those with normal weight.
Article
Nutrition & Dietetics
Gang Hu, Huikun Liu, Junhong Leng, Leishen Wang, Weiqin Li, Shuang Zhang, Wei Li, Gongshu Liu, Huiguang Tian, Shengping Yang, Zhijie Yu, Xilin Yang, Jaakko Tuomilehto
Summary: The purpose of this study was to examine the effects of a 9-month intensive lifestyle intervention on weight loss and cardiovascular risk factors in young women with gestational diabetes mellitus (GDM) and newly diagnosed diabetes. The results showed that the intervention led to significant weight loss, decreased waist circumference, body fat, diastolic blood pressure, fasting glucose, and HbA1c. However, there was a slight increase in HbA1c during the post-intervention period, along with an increased use of glucose-lowering agents.
Review
Nutrition & Dietetics
Ratika Sehgal, Vanessa D. de Mello, Ville Mannisto, Jaana Lindstrom, Jaakko Tuomilehto, Jussi Pihlajamaki, Matti Uusitupa
Summary: The relationship between gut microbiota, diet, and the human body is complex, with tryptophan derivative indolepropionic acid (IPA) playing a crucial role in metabolic and immune functions and in the onset and development of metabolic disorders such as T2D and NAFLD. IPA levels are heavily influenced by diet, particularly dietary fiber, and show significant variations among individuals, which may be partially explained by genetic variants associated with specific diseases like T2D.
Article
Pediatrics
Ming Gao, Hui Wang, Weiqin Li, Leishen Wang, Ninghua Li, Yijuan Qiao, Tao Zhang, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang
Summary: This study found that both maternal insulin resistance and beta-cell dysfunction at diagnosis of gestational diabetes mellitus (GDM) were associated with an increased risk of offspring overweight within 24 months of age among Chinese women.
Article
Endocrinology & Metabolism
Ming Gao, Hui Wang, Weiqin Li, Ping Shao, Ninghua Li, Jinnan Liu, Peng Wang, Shuang Zhang, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang
Summary: There is a relationship between parental obesity before pregnancy and offspring overweight before the age of two among children of Chinese women with gestational diabetes mellitus (GDM). A study in China followed up with 774 offspring of women diagnosed with GDM from 2010-2012 until the age of two. The study found that maternal obesity before pregnancy was associated with an increased risk of offspring overweight at 1-1.5 years and 1.5-2 years of age, while paternal obesity before pregnancy was only associated with an elevated risk of offspring overweight at 1.5-2 years of age. The presence of both maternal and paternal obesity had an additive effect on the risk of offspring overweight at 1.5-2 years of age.
PRIMARY CARE DIABETES
(2023)
Article
Medicine, General & Internal
Yun Shen, Chunfang Wang, Yaxin Wang, Jingyi Lu, Lei Chen, Lei Zhang, Wei Lu, Wei Zhu, Gang Hu, Tian Xia, Jian Zhou
Summary: This study found an inverse association between time in range (TIR) and the risk of cancer mortality among patients with type 2 diabetes. It suggests that TIR may be an optimal target for glycemic control in these patients.
CHINESE MEDICAL JOURNAL
(2022)