4.2 Article

TreeOfTrees Method to Evaluate the Congruence Between Gene Trees

期刊

JOURNAL OF CLASSIFICATION
卷 28, 期 3, 页码 390-403

出版社

SPRINGER
DOI: 10.1007/s00357-011-9093-9

关键词

Congruence; Gene trees; Phylogeny; Tree of trees

资金

  1. OHLL-CNRS
  2. PEPS-CNRS

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A new method, TreeOfTrees, is proposed to compare X-tree structures obtained from several sets of aligned gene sequences of the same taxa. Its aim is to detect genes or sets of genes having different evolutionary histories. The comparison between sets of trees is based on several tree metrics, leading to a unique tree labelled by the gene trees. The robustness values of its edges are estimated by bootstrapping and consensus procedures that allow detecting subsets of genes having differently evolved. Simulations are performed under various evolutionary conditions to test the efficiency of the method and an application on real data is described. Tests of arboricity and various consensus algorithms are also discussed. A corresponding software package is available.

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