Article
Environmental Sciences
Qi Lu, Nan Lin, Xiaomeng Cheng, Tao Yuan, Yan Zhang, Yu Gao, Yankai Xia, Yuning Ma, Ying Tian
Summary: This study developed a fast and sensitive method for the simultaneous analysis of multiple organophosphorus metabolites in urine through solid phase extraction and UPLC-MS/MS detection. The method showed good applicability in assessing human exposures to organophosphates and demonstrated feasibility and reliability for large population-based studies.
Article
Food Science & Technology
Minh Kim Nguyen, Eun Seon Jeong, Kyung Tae Kim, Yong Seok Choi, Dong-Kyu Lee, Sang Beom Han, Jong Seong Kang, Hyung Min Kim
Summary: Organophosphate flame retardants (OPFRs) have been widely used in various consumer items, leading to widespread contamination of environmental systems and detection of their presence in various food items globally. Human exposure to OPFRs through consumption of contaminated food poses potential health risks to both humans and wildlife. However, the analysis of OPFRs in food is challenging due to various factors, including the diverse nature of food matrices and the risk of laboratory contamination. This review discusses the current status of analytical methods used to detect OPFRs in aquatic, agricultural, and livestock-derived food, emphasizing the importance of developing efficient screening methods for these emerging contaminants.
Article
Chemistry, Analytical
Rui-Xin Qin, Bin Tang, Xi Zhuang, Wei-Xiang Lei, Mei-Huan Wang, Luo-Hong Zhang, Ke-Mei Hu
Summary: Indoor dust ingestion is a major pathway for human exposure to organophosphate flame retardants (PFRs), and there are significant correlations between PFR levels in dust and urinary concentrations of diesters (DAPs). This suggests potential sources and pathways of exposure to these chemicals.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2021)
Article
Environmental Sciences
Brigid Carr, Pere Masque, Carlos M. Alonso-Hernandez, David Huertas, Philippe Bersuder, Imma Tolosa
Summary: This study analyzed sediment from Cienfuegos Bay, Cuba to examine the occurrence of organic pollutants from 1990 to 2015. The results showed the presence of regulated contaminants such as PCBs, OCPs, and PBDEs, with a decline in PCB contamination since 2007. Emerging contaminants, including PAEs, OPEs, and aHFRs, showed sharp increases, possibly due to the growing global usage of flame retardants and plasticizer additives. Local sources, such as a plastic recycling plant and urban waste outfalls, may contribute to these trends. Further research is needed to understand the influx of these emerging contaminants.
Article
Environmental Sciences
Yeowool Choi, Chunyan Hao, Paul A. Helm, Satyendra P. Bhavsar, Sang Don Kim
Summary: This study analyzed the concentration and distribution of organophosphate esters (OPEs) in fish samples collected from fishing spots in the North American Great Lakes and nearshore fish samples from the Toronto and Hamilton areas in Canada. The results showed that these chemicals can be ingested by humans through the consumption of fish, but the exposure levels are relatively low compared to exposures through indoor air and dust inhalation.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Analytical
Jishuang Yang, Xia Zhou, Xiuqin Li, Xiaomin Li, Yan Gao, Qinghe Zhang
Summary: This study developed a fast and high throughput method based on the QuEChERS technique combined with GC-QTOF/MS for the simultaneous determination of 21 OPFRs in rice samples. The factors affecting sample pretreatment and GC-QTOF/MS were optimized, and IDMS was used for accurate quantification. The method showed good recoveries and low LOQs, and successfully detected 14 OPFRs in real rice samples within a wide concentration range.
Article
Agriculture, Multidisciplinary
Nannan Zhao, Jie Fu, Yifei Liu, Peilong Wang, Xiaoou Su, Xiaomin Li
Summary: The study found that the concentrations of diesters in animal-derived and plant-derived animal protein supplement feeds are comparable to those of triesters, suggesting that organophosphate diesters may have diverse metabolism capacities and environmental sources.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Engineering, Environmental
Xiangying Zeng, Qiongpu Hu, Jiawen Zhang, Qian Song, Liang Xu, Yi Liang, Yang Wu, Zhiqiang Yu
Summary: The regional characteristics of atmospheric organophosphate triesters (OPEs) and organophosphate diesters (Di-OPs) were investigated in the Pearl River Delta (PRD) using passive air samplers. OPEs were mainly distributed in the central part of the region, possibly due to the presence of industries related to OPE-containing products. Di-OPs, on the other hand, were scattered throughout the PRD, indicating direct industrial emission from their applications. Lower levels of certain compounds were detected in summer, suggesting partitioning off particles and photo-transformation.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Zhongshi Hong, Yachen Li, Xian Deng, Mingliang Chen, Jianpeng Pan, Zhichuan Chen, Xu Zhang, Chunxiao Wang, Chengzhi Qiu
Summary: This study identified and analyzed OPFRs-related genes using the TCGA and CTD databases, and found that OPFRs may be closely related to colorectal cancer (CRC) and associated with a good prognosis. Further experiments demonstrated that one of the OPFRs, triphenyl phosphate, significantly increased the viability and proliferation of CRC cell lines. Additionally, the research found that melatonin had a significant impact on CRC cell proliferation and migration ability induced by TPP.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Environmental Sciences
Qiuyue Zhang, Yu Wang, Chong Zhang, Yiming Yao, Lei Wang, Hongwen Sun
Summary: This study systematically reviewed the source, transfer, and transformation mechanisms of OPEs in the soil environment, pointing out possible sources including wet/dry deposition, air-soil exchange, sewage irrigation, sludge application, etc., while OPEs may migrate into other environmental media via plant uptake, air-soil exchange, causing relevant ecological risks.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Jillian Ashley-Martin, Susan MacPherson, Zhao Zhao, Eric Gaudreau, Gilles Provencher, Mandy Fisher, Michael M. Borghese, Maryse F. Bouchard, Linda Booij, Tye E. Arbuckle
Summary: In this study, urinary concentrations of 15 organophosphate ester (OPE) metabolites in 1865 pregnant women were measured using two analytical methods. The results indicate widespread exposure to OPEs and their metabolites, and identify subpopulations who may have higher exposure.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Environmental Sciences
Chi Yao, Hanpei Yang, Ying Li
Summary: This review provides comprehensive data on the occurrence and impact of organophosphate flame retardants in the environment, focusing on their accumulation, metabolism, and toxic effects in organisms, while also pointing out the current research gaps.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Public, Environmental & Occupational Health
Cheryl Fairfield Estill, Alexander Mayer, Jonathan Slone, I-Chen Chen, Michael Zhou, Mark J. La Guardia, Nayana Jayatilaka, Maria Ospina, Antonia Calafat
Summary: Through evaluating exposure to TPhP among 12 nail salon technicians in California, it was found that there were significant differences in concentrations of TPhP in air, hand wipe, and urine samples, with post-shift concentrations of TPhP being significantly higher than pre-shift concentrations.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2021)
Article
Environmental Sciences
Oscar Aznar-Alemany, Berta Sala, Karl J. Jobst, Eric J. Reiner, Asuncion Borrell, Alex Aguilar, Ethel Eljarrat
Summary: The levels of PBDEs in the muscle of striped dolphins from the Mediterranean Sea decreased by about 60% over three decades, with BDE-47, -99, -154, -100, and -153 as the main contributors. Additionally, alpha-HBCD was found in the majority of samples and remained stable over time.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Cassidy Clarity, Jessica Trowbridge, Roy Gerona, Katherine Ona, Michael McMaster, Vincent Bessonneau, Ruthann Rudel, Heather Buren, Rachel Morello-Frosch
Summary: The study found that female firefighters are more likely to be affected by chemical exposures compared to office workers, with a significant positive association between chemical exposures and telomere length. These results suggest potential mechanisms by which chemicals may impact carcinogenesis and other adverse health outcomes.
ENVIRONMENTAL HEALTH
(2021)
Article
Environmental Sciences
Jianan Huang, Langjie Ye, Mingliang Fang, Guanyong Su
Summary: With the phase-out of traditional halogenated flame retardants, research interests have shifted to organophosphate flame retardants (OPFRs). This study conducted an extensive survey to identify the OPFRs currently being produced in factories and investigate their annual production volume (APV). Results indicate that there are at least 56 OPFR monomers and 62 OPFR mixtures being produced in 367 factories worldwide, with 201 of them located in Mainland China. The estimated APV of OPFRs is 598,422 metric tons, which may be underestimated due to limited information availability. The study also highlights the limited research on certain types of OPFRs and provides recommendations for future research in this area.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2022)
Article
Environmental Sciences
Ming Zhu, Huijun Su, Yurong Bao, Jianhua Li, Guanyong Su
Summary: In this study, experimental octanol-water partition coefficients (K-OW) of 39 liquid crystal monomers (LCMs) were measured, showing variations depending on specific structures with values generally falling in the range of 4.94-7.62. A quantitative structure activity relationship (QSAR) model was established based on the experimental data to predict values for LCMs without authentic standards, achieving a goodness-of-fit with a determination coefficient (R-2) of 0.810. The study suggests that LCMs tend to accumulate in the fatty tissue of organisms in aqueous environments.
Article
Engineering, Environmental
Zhipeng Cheng, Qingyang Shi, Yu Wang, Leicheng Zhao, Xiaoxiao Li, Zhaoyang Sun, Yuan Lu, Na Liu, Guanyong Su, Lei Wang, Hongwen Sun
Summary: Liquid crystal monomers (LCMs) in liquid crystal displays (LCDs) can be released into the environment, posing a high occupational exposure risk. Fluorinated biphenyls and their analogs are the dominant LCMs found in commonly used smartphones and computers. Various LCMs were also detected in samples from an e-waste recycling industrial park, particularly in outdoor dust and indoor dust from workshops.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Jianan Huang, Zhanqi Gao, Guanjiu Hu, Guanyong Su
Summary: By using an integrated screening strategy, the occurrence and distribution of OPEs in different water samples from Jiangsu Province, China were investigated. The results showed variations in spatial distribution and concentration, with groundwater exhibiting the highest concentration due to pollution from surrounding factories. Among the target OPEs, TEP, TCEP, and TCIPP were the most abundant congeners. In addition, suspect OPEs and non-target OPs were also identified through screening and analysis.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Engineering, Environmental
Danyang Tao, Qianqian Jin, Yuefei Ruan, Kai Zhang, Linjie Jin, Yuting Zhan, Guanyong Su, Jiaxue Wu, Kenneth M. Y. Leung, Paul K. S. Lam, Yuhe He
Summary: Liquid crystal monomers (LCMs), commonly used in screens of electronic devices, have been identified as potential threats to the marine ecosystem. This study investigated the pollution status of LCMs in the Pearl River Estuary (PRE), where primitive handling of e-waste is widespread. The results showed a widespread occurrence of LCMs in sediments, with a gradient of contamination from inshore to offshore regions. Preliminary risk assessment identified certain LCMs as top contributors to the risk in the PRE. Further investigation on the ecological impact of LCMs, as well as source identification and control measures, are necessary.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Ruifeng Bi, Guanyong Su
Summary: An integrated screening strategy was applied to analyze OPEs in 107 foodstuffs collected from Nanjing City, China in 2020. The results showed that meat samples were the most severely contaminated. Additionally, suspect and non-target analysis identified other OPEs, providing important information for food safety assessment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Yurong Bao, Ming Zhu, Guanyong Su
Summary: This study investigated the bioaccumulation, tissue-specific accumulation, and depuration properties of liquid crystal monomers (LCMs) in adult zebrafish. The study found that the accumulation potential of LCMs varied among different functional groups, and LCMs with the cyan group were more likely to accumulate in zebrafish. The study also suggested that the bioaccumulation potential of some LCMs in aquatic environments might be overestimated by theoretical estimation techniques.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Rongrong Li, Kefan Ren, Huijun Su, Yu Wei, Guanyong Su
Summary: Recent studies have found the widespread presence of liquid crystal monomers (LCMs) in various environments, but there is limited information about their contamination in soil. This study collected soil samples from different urban functional zones and found that LCMs are widely distributed in surface soil. The agricultural zone had the highest concentration of LCMs, followed by commercial, residential, industrial, and scenic zones. Correlations between different LCMs were also observed, suggesting similar commercial applications and sources.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Correction
Engineering, Environmental
Kainan Nian, Wenhui Yang, Xuesheng Zhang, Rui Zhang, Wenli Xiong, Doug Crump, Guanyong Su, Xiaowei Zhang, Mingbao Feng, Jiaqi Shi
Article
Environmental Sciences
Yi Kong, Yong Wen, Guanyong Su, Ying Peng, Xinyi Cui
Summary: Increasing evidence suggests that liquid crystal monomers (LCMs) in liquid crystal displays can be released into the environment and detected in environmental matrices and human bodies. However, there is a lack of databases regarding their uptake and distribution in mammals. This study investigated the distribution and accumulation of four LCMs in mice tissues, revealing their preferential deposition in lipophilic tissues and the influence of physico-chemical properties on their distribution and accumulation. These findings have important implications for biomonitoring and risk assessment of LCMs.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Engineering, Environmental
Haoduo Zhao, Caixia Li, Mihir Yogesh Naik, Jia Wu, Angelysia Cardilla, Min Liu, Fanrong Zhao, Shane Allen Snyder, Yun Xia, Guanyong Su, Mingliang Fang
Summary: Liquid crystal monomers (LCMs) are commonly used in liquid crystal display (LCD) industries, but their environmental occurrences and toxic effects have not been thoroughly studied. This study used in silico simulation, in vitro assays, and omics integration analysis to comprehensively investigate the toxicity and mechanism of LCMs. The results showed that certain LCMs significantly antagonized peroxisome proliferator-activated receptor gamma (PPARγ), leading to dysregulation of metabolome and transcriptome in HK2 cells. Dysregulation of fatty acid beta-oxidation, mediated through multiple pathways, and the activation of AMPK and ligand-dependent PPARγ antagonism were identified to play important roles. This study provides valuable insights for future chemical risk assessment.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Weigao Zhang, Jiapeng Jie, Qian Xu, Rong Wei, Xin Liao, Danyang Zhang, Yayun Zhang, Jianfa Zhang, Guanyong Su, Yuxin Chen, Dan Weng
Summary: The incidence of obesity and non-alcoholic fatty liver disease (NAFLD) has been increasing rapidly worldwide. Environmental factors such as plastic usage and chemical exposure have been suggested to be important contributors to the obesity epidemic. Acetyl tributyl citrate (ATBC), a commonly used non-phthalate plasticizer, has a high leakage rate from plastics, leading to increased exposure risk. This study aimed to evaluate the safety of subchronic exposure to environmentally-relevant concentrations of ATBC. Results showed that ATBC exposure led to weight gain, increased body fat content, larger adipocytes, and liver steatosis in mice. In vitro experiments also demonstrated increased intracellular lipid accumulation with ATBC treatment.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Weikun Meng, Hao Sun, Guanyong Su
Summary: Plastic packaging contains residues from manufacturing substances and non-intentionally added substances (NIAS), such as impurities and degradation products. The study found that there are over 10,259 chemicals related to plastic packaging materials, and it discussed their structure, analysis methods, migration characteristics, and potential hazards.
Article
Environmental Sciences
Ruifeng Bi, Weikun Meng, Guanyong Su
Summary: An integrated screening method was optimized using UHPLC-HRMS to investigate the migration of OPEs from plastic food packaging. A total of 42 OPEs were identified, including seven new ones, in 106 samples collected in Nanjing, China. The study also revealed the oxidation products of AO626 in plastics, suggesting the importance of the oxidation of OPAs as an indirect source of OPEs. Migration of OPEs was observed in four simulated foods, with diverse OPEs detected at elevated concentrations in isooctane.
ENVIRONMENT INTERNATIONAL
(2023)
Review
Environmental Sciences
Miaolei Ya, Yuling Wu, Xinhong Wang, Yongyu Li, Guanyong Su
Summary: The sources of carcinogenic polycyclic aromatic hydrocarbons (PAHs), which are by-products of the combustion of organic matter, have been extensively studied in the fields of environmental monitoring, environmental forensics, and organic geochemistry. Various methods, including molecular diagnostic ratios, receptor models, and stable isotope analysis, have been used to identify the sources of PAHs. However, these conventional methods have limitations that lead to ambiguous results. Compound-specific radiocarbon analysis (CSRA) is a more effective method that focuses on molecular level radiocarbon signatures to identify the sources of PAHs. CSRA has the ability to distinguish the contributions of fossil fuels and biomass burning. In this review, we highlight the advantages of CSRA and its application and prospects in PAH source identification, providing a critical resource to expand the application of CSRA in environmental science. This is the first comprehensive review of the application of CSRA for PAH source identification.
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
