Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue

Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers

(2015) F. F. Wagner et al.   Chemical Science

Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus

(2014) Martina Blank et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Epigenetic modifications in the nervous system and their impact upon cognitive impairments

(2014) Andrii Rudenko et al.   NEUROPHARMACOLOGY

The Potential of HDAC Inhibitors as Cognitive Enhancers

(2013) Johannes Gräff et al.   Annual Review of Pharmacology and Toxicology

HDAC3 Is a Negative Regulator of Cocaine-Context-Associated Memory Formation

(2013) G. A. Rogge et al.   JOURNAL OF NEUROSCIENCE

Loss of Histone Deacetylase 2 Improves Working Memory and Accelerates Extinction Learning

(2013) M. J. Morris et al.   JOURNAL OF NEUROSCIENCE

Exercise and Sodium Butyrate Transform a Subthreshold Learning Event into Long-Term Memory via a Brain-Derived Neurotrophic factor-Dependent Mechanism

(2013) Karlie A Intlekofer et al.   NEUROPSYCHOPHARMACOLOGY

Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma

(2013) Christina E. Wells et al.   PLoS One

HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

(2013) M. Malvaez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin–proteasomal and autophagy systems

(2012) Haiqun Jia et al.   HUMAN MOLECULAR GENETICS

Epigenetic Modulation of Homer1a Transcription Regulation in Amygdala and Hippocampus with Pavlovian Fear Conditioning

(2012) A. L. Mahan et al.   JOURNAL OF NEUROSCIENCE

Targeting Synaptic Dysfunction in Alzheimer’s Disease Therapy

(2012) Robert Nisticò et al.   MOLECULAR NEUROBIOLOGY

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity

(2012) Daniel M. Fass et al.   NEUROPHARMACOLOGY

Synaptic changes in Alzheimer’s disease and its models

(2012) J. Pozueta et al.   NEUROSCIENCE

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

(2011) S. C. McQuown et al.   JOURNAL OF NEUROSCIENCE

Post-training intrahippocampal inhibition of class I histone deacetylases enhances long-term object-location memory

(2011) J. D. Hawk et al.   LEARNING & MEMORY

The path to epigenetic treatment of memory disorders

(2011) Mikael A. Mikaelsson et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity

(2011) Stephen J. Haggarty et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Epigenetic Mechanisms in Cognition

(2011) Jeremy J. Day et al.   NEURON

Epigenetic Alterations Are Critical for Fear Memory Consolidation and Synaptic Plasticity in the Lateral Amygdala

(2011) Melissa S. Monsey et al.   PLoS One

Synapse microarray identification of small molecules that enhance synaptogenesis

(2011) Peng Shi et al.   Nature Communications

Modulation of Chromatin Modification Facilitates Extinction of Cocaine-Induced Conditioned Place Preference

(2009) Melissa Malvaez et al.   BIOLOGICAL PSYCHIATRY

Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function

(2009) M. W. Akhtar et al.   JOURNAL OF NEUROSCIENCE

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development

(2008) Jessica L. MacDonald et al.   DEVELOPMENTAL DYNAMICS

Dendritic Spine Loss and Synaptic Alterations in Alzheimer’s Disease

(2008) Marlen Knobloch et al.   MOLECULAR NEUROBIOLOGY

HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

(2008) Myriam Rai et al.   PLoS One

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

(2008) E. A. Thomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA