Article
Biochemical Research Methods
Ann Gogolashvili, Ketevan Lomsadze, Lali Chankvetadze, Nino Takaishvili, Paola Peluso, Roberto Dallocchio, Antonio Salgado, Bezhan Chankvetadze
Summary: The study investigated the recognition power and affinity patterns of various cyclodextrins towards the enantiomers of tetrahydrozoline using capillary electrophoresis. The affinity and selectivity were strongly influenced by the cavity size and substituent type on the cyclodextrin rims. It was also found that enantiomers exhibited opposite affinity patterns towards different cyclodextrins.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Review
Chemistry, Analytical
Bezhan Chankvetadze, Gerhard K. E. Scriba
Summary: This review highlights the potential of capillary electrophoresis in understanding the fine structural mechanisms of noncovalent interactions and enantioselective intermolecular recognition for cyclodextrins and their guests. The importance of additional experimental and molecular modeling tools is emphasized, with the concept illustrated by recent literature. The authors also provide their critical opinion on certain current tendencies.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Yuan Zhao, Xuecheng Zhu, Wei Jiang, Huilin Liu, Baoguo Sun
Summary: With the rapid development of global industry and increasing product circulation, the separation and detection of chiral drugs/pesticides are becoming increasingly important due to their potential harm to the human body. Chromatography and membrane-based enantioseparation techniques play a vital role in specific recognition and resolution of chiral molecules, with wide practical applications in various industries. Recent advancements and future prospects in chromatographic and membrane-based enantioseparations have been discussed, highlighting their unique properties for selective separation and identification of chiral substances.
Review
Food Science & Technology
Ana M. Jimenez-Carvelo, Luis Cuadros-Rodriguez
Summary: Foodomics aims to investigate the effects of food on health by collecting and analyzing data using data mining methods, often implemented on specific platforms due to researchers' lack of experience. This paper provides an overview of the latest research advances in data analysis processes in untargeted approaches, mainly using analytical techniques such as NMR, chromatography-MS, and 2D chromatography, while emphasizing the gaps that still need to be filled in the use of data mining methods. Additionally, it explains and discusses the terminology used in this field.
CURRENT OPINION IN FOOD SCIENCE
(2021)
Review
Chemistry, Physical
Zhenglong Li, Maryom Rahman, Sreerag Kaaliveetil, Niranjan Haridas, Yu-Hsuan Cheng, Charmi Chande, Sagnik Basuray
Summary: This article presents the recent developments in spectroelectrochemistry (SEC), particularly focusing on the less frequently used but promising nuclear magnetic resonance (NMR) and dark field microscopy (DFM) techniques. It also discusses the application of SEC techniques in microfluidics and highlights the challenges and future perspectives in this field.
CURRENT OPINION IN ELECTROCHEMISTRY
(2023)
Article
Chemistry, Analytical
Lujun Wang, Wanli Gao, Siowwoon Ng, Martin Pumera
Summary: This study introduces a 3D-printed electrochemical chiral sensor functionalized with magnetic COF and BSA, showing excellent chiral recognition ability towards L-Trp compared to D-Trp. The sensor can be used for determining the concentration of L-Trp in a racemic mixture. This on-demand fabrication of protein-COF-modified electrodes offers new approaches for enantiomer recognition.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Laura A. Voelker, Konstantin Herb, Erika Janitz, Christian L. Degen, John M. Abendroth
Summary: In this study, a quantum sensing scheme is introduced to directly measure the hypothesized spin polarization in radical pairs using shallow nitrogen-vacancy (NV) centers in diamond. This method provides fresh insights into spin selectivity in electron transfer reactions.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Chemistry, Analytical
Qianqian Zhao, Wenkai Zhu, Wenrong Cai, Junyao Li, Datong Wu, Yong Kong
Summary: A bifunctional electrochemiluminescent platform for chiral discrimination and chiral sensing has been constructed. The platform utilizes the synergistic effect between CdSe quantum dots and TiO2 nanotubes to effectively discriminate the isomers of nine chiral amino acids and detect D-amino acids sensitively.
ANALYTICAL CHEMISTRY
(2022)
Review
Medicine, General & Internal
Isabella Leo, Mahesh Vidula, Giandomenico Bisaccia, Maria Cristina Procopio, Roberto Licordari, Maria Perotto, Giulia La Vecchia, Nikolaos Miaris, Paco E. Bravo, Chiara Bucciarelli-Ducci
Summary: Advances in cancer therapies have led to improved patient survival rates, but have also increased the risk of cardiovascular complications. Both cancer and cardiovascular diseases share common factors such as inflammation and immune system disturbances. Novel biological therapies, especially immunotherapy, have more pronounced effects on the immune system. Therefore, there is growing interest in understanding the molecular role of the immune system in cardiotoxicity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemical Research Methods
Elena Reshetova, Leonid Asnin
Summary: The retention and separation behavior of enantiomers of amine derivatives of indane and tetralin (rasagiline and its analogues) on chiral stationary phases (CSPs) Chiral-T and Chiral-V was studied under conditions of reversed-phase and polar organic chromatography. The effects of molecular structure and physical properties of the analytes on enantioselective retention were discussed. The retention mechanism is hypothesized to involve ion-ion attraction between the analytes and the antibiotics. The effect of mobile phase solvent composition on retention and enantioseparation was also investigated.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Multidisciplinary Sciences
M. Sebastiana, A. Gargallo-Garriga, J. Sardans, M. Perez-Trujillo, F. Monteiro, A. Figueiredo, M. Maia, R. Nascimento, M. Sousa Silva, A. N. Ferreira, C. Cordeiro, A. P. Marques, L. Sousa, R. Malho, J. Penuelas
Summary: Studies using metabolomics and transcriptomics approaches revealed that in ectomycorrhizal cork oak roots colonized by Pisolithus tinctorius fungus, certain compounds like carbohydrates and fatty acids were depleted, while non-proteogenic amino acids and defense-related compounds were induced. This indicates a potential mechanism to enhance symbiosis and activate defense pathways in roots.
SCIENTIFIC REPORTS
(2021)
Review
Chemistry, Analytical
Dongyang Ye, Xiaowei Li, Jianzhong Shen, Xi Xia
Summary: Microbial metabolomics is an important field in systems biology, focusing on the analysis of metabolites in microorganisms. The complexity and diversity of microbial metabolites have hindered its progress, but with the development of new analytical techniques, microbial metabolomics has gained more attention for its ability to elucidate metabolic pathways and microbial-host interactions.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Minjian Dong, Qingqing Yi, Danjie Shen, Jiapin Yan, Haowei Jiang, Jiaojiao Xie, Liangcai Zhao, Hongchang Gao
Summary: This study aimed to investigate the effects of chronic (L)-lactate exposure on peripheral tissues in mice and the underlying pathogenesis. The results revealed that chronic (L)-lactate exposure caused hepatocyte dysfunction in mice through increased oxidative stress and apoptosis.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2022)
Article
Food Science & Technology
Shenghao Wang, Guoyin Lai, Jianzhong Lin, Feng Xia, Zenan Ding, Jianghua Feng, Jingjing Xu, Guiping Shen
Summary: This study successfully identified adulterated olive oil with different ratios of soybean oil or corn oil using low-field nuclear magnetic resonance (LF-NMR) combined with multivariate statistical analysis. Significant differences in relaxation time and peak area proportions were detected between pure and adulterated olive oil, allowing for accurate classification through principal component analysis (PCA) or partial least squares discriminant analysis (PLS-DA) with at least 20% adulteration. The research demonstrates the promising potential of LF-NMR combined with pattern recognition for rapid screening of edible oils.
FOOD ANALYTICAL METHODS
(2021)
Review
Chemistry, Multidisciplinary
Florence Franconi, Laurent Lemaire, Jean-Christophe Gimel, Samuel Bonnet, Patrick Saulnier
Summary: NMR-based diffusion methods are valuable tools for nanomedicine characterization and understanding interactions with the biological environment. They provide insights into diffusion phenomena and measurement of self-diffusion and mutual diffusion coefficients. NMR diffusometry spectroscopic and imaging methods have broad applications in nanomedicine, aiding in elucidating important issues.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Chemistry, Medicinal
Gloria Uccello Barretta, Alessandro Mandoli, Federica Balzano, Federica Aiello, Beatrice De Nicola, Alessandro Del Grande
Article
Chemistry, Analytical
Gloria Uccello-Barretta, Federica Balzano, Federica Aiello, Niccolo Falugiani, Ielizza Desideri
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2015)
Article
Chemistry, Multidisciplinary
Sofia Masi, Aurora Rizzo, Federica Aiello, Federica Balzano, Gloria Uccello-Barretta, Andrea Listorti, Giuseppe Gigli, Silvia Colella
Article
Chemistry, Organic
Gloria Uccello-Barretta, Federica Balzano, Federica Aiello, Letizia Vanni, Mattia Mori, Sergio Menta, Andrea Calcaterra, Bruno Botta
ORGANIC & BIOMOLECULAR CHEMISTRY
(2015)
Article
Chemistry, Multidisciplinary
Gloria Uccello Barretta, Federica Balzano, Federica Aiello, Francesca Nardelli, Alessia Ciogli, Andrea Calcaterra, Bruno Botta
SUPRAMOLECULAR CHEMISTRY
(2016)
Article
Chemistry, Organic
Valeria Di Bussolo, Ileana Frau, Lucilla Favero, Gloria Uccello-Barretta, Federica Balzano, Paolo Crotti
Article
Chemistry, Organic
Federica Aiello, Federica Balzano, Francesca Ghirga, Ilaria D'Acquarica, Bruno Botta, Gloria Uccello-Barretta, Deborah Quaglio
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2017)
Article
Pharmacology & Pharmacy
Angela Fabiano, Anna Maria Piras, Gloria Uccello-Barretta, Federica Balzano, Andrea Cesari, Lara Testai, Valentina Citi, Ylenia Zambito
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2018)
Article
Chemistry, Multidisciplinary
Sofia Masi, Federica Aiello, Andrea Listorti, Federica Balzano, Davide Altamura, Cinzia Giannini, Rocco Caliandro, Gloria Uccello-Barretta, Aurora Rizzo, Silvia Colella
Article
Chemistry, Applied
Gloria Uccello-Barretta, Federica Balzano, Letizia Vanni, Marco Sanso
CARBOHYDRATE POLYMERS
(2013)
Article
Chemistry, Medicinal
Ilaria D'Acquarica, Andrea Calcaterra, Fabiola Sacco, Federica Balzano, Federica Aiello, Andrea Tafi, Nicolo Pesci, Gloria Uccello-Barretta, Bruno Botta
Article
Chemistry, Medicinal
Gloria Uccello-Barretta, Volker Schurig, Federica Balzano, Letizia Vanni, Federica Aiello, Mattia Mori, Francesca Ghirga
Article
Pharmacology & Pharmacy
Gloria Uccello-Barretta, Federica Balzano, Federica Aiello, Alessandro Senatore, Angela Fabiano, Ylenia Zambito
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2014)
Article
Pharmacology & Pharmacy
Yun Yu, Yu Lu, Ruonan Bo, Yee Huang, Yuanliang Hu, Jiaguo Liu, Yi Wu, Yang Tao, Deyun Wang
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2014)
Article
Chemistry, Organic
Valeria Di Bussolo, Ileana Frau, Stefano Crotti, Gloria Uccello-Barretta, Federica Balzano, Mauro Pineschi, Paolo Crotti
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)