Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice

SustainedN-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling

(2014) Mark J. Ferris et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NMDA receptor-deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities

(2014) M. Milenkovic et al.   GENES BRAIN AND BEHAVIOR

Unmet Needs in the Treatment of Schizophrenia

(2014) Leslie Citrome   JOURNAL OF CLINICAL PSYCHIATRY

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Animal models for predicting the efficacy and side effects of antipsychotic drugs

(2014) Pedro H. Gobira et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis

(2013) Stefan Leucht et al.   LANCET

Assessment of subjective cognitive and emotional effects of antipsychotic drugs. Effect by defect?

(2013) Steffen Moritz et al.   NEUROPHARMACOLOGY

The possible role of the Akt signaling pathway in schizophrenia

(2012) Wenhua Zheng et al.   BRAIN RESEARCH

α-Lipoic Acid Interaction with Dopamine D2 Receptor-Dependent Activation of the Akt/GSK-3β Signaling Pathway Induced by Antipsychotics: Potential Relevance for the Treatment of Schizophrenia

(2012) Jessica Deslauriers et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents

(2012) S Miyamoto et al.   MOLECULAR PSYCHIATRY

The role of 5-HT1A receptors in phencyclidine (PCP)-induced novel object recognition (NOR) deficit in rats

(2012) M. Horiguchi et al.   PSYCHOPHARMACOLOGY

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Differential effects of amisulpride and haloperidol on dopamine D2 receptor-mediated signaling in SH-SY5Y cells

(2011) Sung Woo Park et al.   NEUROPHARMACOLOGY

Discovery of  -Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

(2011) J. A. Allen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced Cortical BDNF Expression and Aberrant Memory in Carf Knock-Out Mice

(2010) K. A. McDowell et al.   JOURNAL OF NEUROSCIENCE

Behavioral Indices in Antipsychotic Drug Discovery

(2010) R. D. Porsolt et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Conditioned Avoidance Response in the Development of New Antipsychotics

(2009) M-L. Wadenberg   CURRENT PHARMACEUTICAL DESIGN

Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia

(2009) T. B. Halene et al.   GENES BRAIN AND BEHAVIOR

How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials

(2008) S Leucht et al.   MOLECULAR PSYCHIATRY

Antagonism of dopamine D2 receptor/ -arrestin 2 interaction is a common property of clinically effective antipsychotics

(2008) B. Masri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA