Optogenetic Activation of Adenosine A2A Receptor Signaling in the Dorsomedial Striatopallidal Neurons Suppresses Goal-Directed Behavior

Behavioral flexibility is increased by optogenetic inhibition of neurons in the nucleus accumbens shell during specific time segments

(2014) L. Aquili et al.   LEARNING & MEMORY

A critical time window for dopamine actions on the structural plasticity of dendritic spines

(2014) S. Yagishita et al.   SCIENCE

Regulation of Fear Responses by Striatal and Extrastriatal Adenosine A2A Receptors in Forebrain

(2013) Catherine J. Wei et al.   BIOLOGICAL PSYCHIATRY

Adenosine Transporter ENT1 Regulates the Acquisition of Goal-Directed Behavior and Ethanol Drinking through A2A Receptor in the Dorsomedial Striatum

(2013) H. W. Nam et al.   JOURNAL OF NEUROSCIENCE

Ecto-5'-Nucleotidase (CD73)-Mediated Formation of Adenosine Is Critical for the Striatal Adenosine A2A Receptor Functions

(2013) E. Augusto et al.   JOURNAL OF NEUROSCIENCE

A causal link between prediction errors, dopamine neurons and learning

(2013) Elizabeth E Steinberg et al.   NATURE NEUROSCIENCE

Adenosine receptors as drug targets — what are the challenges?

(2013) Jiang-Fan Chen et al.   NATURE REVIEWS DRUG DISCOVERY

Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors

(2013) Eric J. Nunes et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Operant Self-Stimulation of Dopamine Neurons in the Substantia Nigra

(2013) Mark A. Rossi et al.   PLoS One

Adenosine A2A Receptors in Striatal Glutamatergic Terminals and GABAergic Neurons Oppositely Modulate Psychostimulant Action and DARPP-32 Phosphorylation

(2013) Hai-Ying Shen et al.   PLoS One

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions

(2013) Christina M. Gremel et al.   Nature Communications

Deletion of striatal adenosine A2A receptor spares latent inhibition and prepulse inhibition but impairs active avoidance learning

(2012) Philipp Singer et al.   BEHAVIOURAL BRAIN RESEARCH

SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance

(2012) Cristiano Nazzaro et al.   NATURE NEUROSCIENCE

Transient stimulation of distinct subpopulations of striatal neurons mimics changes in action value

(2012) Lung-Hao Tai et al.   NATURE NEUROSCIENCE

Disruption in the Balance Between Goal-Directed Behavior and Habit Learning in Obsessive-Compulsive Disorder

(2011) Claire M. Gillan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Differential regulation of motor control and response to dopaminergic drugs by D1R and D2R neurons in distinct dorsal striatum subregions

(2011) Pierre F Durieux et al.   EMBO JOURNAL

Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens

(2011) M. Lazarus et al.   JOURNAL OF NEUROSCIENCE

Selective inactivation of adenosine A2A receptors in striatal neurons enhances working memory and reversal learning

(2011) C. J. Wei et al.   LEARNING & MEMORY

Motor Sequences and the Basal Ganglia: Kinematics, Not Habits

(2010) M. Desmurget et al.   JOURNAL OF NEUROSCIENCE

Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors

(2010) Michael J Higley et al.   NATURE NEUROSCIENCE

Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease

(2010) Peter Redgrave et al.   NATURE REVIEWS NEUROSCIENCE

Differential Dynamics of Activity Changes in Dorsolateral and Dorsomedial Striatal Loops during Learning

(2010) Catherine A. Thorn et al.   NEURON

Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum

(2010) David M. Lovinger   NEUROPHARMACOLOGY

Preferential enhancement of working memory in mice lacking adenosine A2A receptors

(2009) Sai-jun Zhou et al.   BRAIN RESEARCH

Commentary of “Brown Gould B, Graybiel AM. Afferents to the Cerebellar Cortex in the Cat: Evidence for an Intrinsic Pathway Leading from the Deep Nuclei to the Cortex. Brain Research 1976;110:601–611”

(2009) Duane E. Haines et al.   CEREBELLUM

Genetic Deletion of A2A Adenosine Receptors in the Striatum Selectively Impairs Habit Formation

(2009) C. Yu et al.   JOURNAL OF NEUROSCIENCE

D2R striatopallidal neurons inhibit both locomotor and drug reward processes

(2009) Pierre F Durieux et al.   NATURE NEUROSCIENCE

Learning Substrates in the Primate Prefrontal Cortex and Striatum: Sustained Activity Related to Successful Actions

(2009) Mark H. Histed et al.   NEURON

The integrative function of the basal ganglia in instrumental conditioning

(2008) Bernard W. Balleine et al.   BEHAVIOURAL BRAIN RESEARCH

Reward-guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico-basal ganglia networks

(2008) Henry H. Yin et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NMDA Receptor Gating of Information Flow through the Striatum In Vivo

(2008) P. E. Pomata et al.   JOURNAL OF NEUROSCIENCE

Nucleus Accumbens Adenosine A2A Receptors Regulate Exertion of Effort by Acting on the Ventral Striatopallidal Pathway

(2008) S. Mingote et al.   JOURNAL OF NEUROSCIENCE