Article
Chemistry, Analytical
M. C. Villegas-Alvarez, A. Arias-Borrego, I. Velasco, T. Garcia-Barrera
Summary: Sample treatment is a bottleneck in untargeted metabolomics, especially for complex samples like food or biofluids. This study developed a new analytical extraction method called three-phase-UA-HF-LPME, which improved the extraction efficiency and was validated using human milk. The method showed better sensitivity, enrichment factors, and metabolite coverage compared to the conventional liquid-liquid extraction method.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Leyla Haidari-Khoshkelat, Jahan Bakhsh Raoof, Milad Ghani, Reza Ojani
Summary: In this study, a combination of two extraction techniques was used to analyze antibiotics in water and urine samples. The method was found to accurately quantify the selected analytes and was applicable to complex biological samples.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Anel Kapar, Aset Muratuly, Dina Orazbayeva, Nadezhda V. Bakaikina, Bauyrzhan Bukenov, Bulat Kenessov
Summary: A computational model for predicting the effect of temperature on the extraction of VOCs from air onto PDMS-based SPME coating has been developed using COMSOL Multiphysics(R) software. This model provides a faster and more accurate method for optimization and modeling by selecting suitable methods and models for estimating diffusion coefficients and coating-air distribution constants.
ANALYTICA CHIMICA ACTA
(2022)
Article
Multidisciplinary Sciences
Seung-Hyun Yang, Hoon Choi
Summary: A reliable residue analysis method using HILIC-LC-MS/MS was developed for simultaneous detection of several nereistoxin compounds in animal-origin foods. The method demonstrated good limit of quantitation, linearity, and recovery efficiency, satisfying the criteria outlined in international guidelines.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Chemical
Jian Song, Zhigang Wang, Xiaoyao Tan, Yifan Cui, Sibudjing Kawi, Shaomin Liu
Summary: A BCFS perovskite hollow fiber membrane was prepared by phase inversion and sintering technique with the addition of Co2O3 to enhance mechanical strength and reduce sintering temperature. The membrane exhibits simultaneous permeation of hydrogen and oxygen, showing potential as a catalytic membrane reactor for various reactions. Simultaneous permeation enhances hydrogen and oxygen fluxes by reducing gas concentrations and promoting gas/ion exchange reactions.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Engineering, Electrical & Electronic
Yu Wang, Jihong Tao, Weihao Yuan, Zhenggang Lian, Qiang Ling, Daru Chen, Zhangwei Yu, Chao Lu
Summary: In this study, a novel optical fiber sensor for simultaneous measurement of high temperature and gas pressure was proposed and experimentally demonstrated using a Regenerated Fiber Bragg grating (RFBG) cascaded with a homemade hollow core Bragg fiber (HCBF). The sensor exhibited high linear pressure and temperature sensitivity in a large dynamic range, and a 2x2 matrix obtained from experimental results enabled simultaneous measurement of temperature and gas pressure. Compact size, low cost, and high sensitivity make this sensor competitive for harsh environment applications.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2021)
Article
Biochemical Research Methods
Arne Werner
Summary: RNA double strand hybridization is a crucial process in gene expression regulation, and this study determined the dissociation constants of complementary equally sized RNA single strands using fluorescence correlation spectroscopy at the single molecule level. The dissociation constants for different lengths of dsRNA were measured, and the translational diffusion coefficients of RNA at infinite dilution were accurately predicted.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Optics
Diana Pereira, Joerg Bierlich, Jens Kobelke, Marta S. Ferreira
Summary: In this study, a hybrid sensor based on hollow square core fiber (HSCF) was proposed for refractive index measurement of liquids. The sensor operates in transmission mode and consists of two interferometers with different sensitivities to external refractive index and temperature. A compensation method was developed to realize temperature-independent refractive index measurements.
Article
Engineering, Electrical & Electronic
Bingsen Huang, Xinzhi Sheng, Jiaqi Cao, Shuqin Lou
Summary: A compact sensor integrated in a single hollow core Bragg fiber is proposed for simultaneous measurement of strain and temperature. Both Mach-Zehnder interferometer and Bragg resonant mechanism are coexisting in the sensor. The sensor has good linearity and achieves simultaneous measurement of temperature and strain with axial strain sensitivities of -0.4 and 0.33 pm/με, and temperature sensitivities of 40.8 and 26.5 pm/°C.
IEEE SENSORS JOURNAL
(2023)
Article
Biochemical Research Methods
Fatemeh Darvishnejad, Jahan Bakhsh Raoof, Milad Ghani, Reza Ojani
Summary: A copper-chromium-layered double hydroxide (Cu/Cr-LDH) was synthesized by the co-precipitation method and intercalated with Keggin-type polyoxometalate (H3PW12O40). The modified LDH was used for the extraction of chlorophenols from water and tea samples using the HF-solid phase microextraction method (HF-SPME). The method showed good performance with high enrichment factors and accurate quantification of the target analytes.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
Yang Liu, Tao Wu, Qiang Wu, Weidong Chen, Chenwen Ye, Mengyu Wang, Xingdao He
Summary: The laser frequency-locked hollow waveguide (HWG) gas sensor demonstrated simultaneous measurements of three isotopologues with enhanced accuracy and precision under the frequency locking condition. This study showcases the high potential of a novel human breath diagnostic sensor for medical diagnostic with high accuracy, precision, and sensitivity.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Behrouz Seyfinejad, Kimiya Jouyban, Ahmad Reza Dehpour, Razieh Mohammad Jafari, Mohammad Charkhpour, Mohammad Reza Afshar Mogaddam, Abolghasem Jouyban
Summary: The development of an ion-pair hollow fiber liquid-phase microextraction (IP-HF-LPME) procedure combined with capillary electrophoresis (CE) and indirect UV detection for the simultaneous extraction and determination of aliphatic biogenic amines in rat tissue samples was described. The CE separation and indirect UV detection conditions, as well as the IP-HF-LPME extraction conditions, were studied and optimized. The method demonstrated good performance in terms of linearity, recovery, sensitivity, and repeatability. The detection limits ranged from 2.8 to 4.5 ng mL-1, with a quantification limit of 15 ng mL-1 and a dynamic range of 15-2000 ng mL-1.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Biochemical Research Methods
Vilma del Carmen Salvatierra-Stamp, Silvia G. Ceballos-Magana, Norma Susana Pano-Farias, Jose Belisario Leyva-Morales, Kayim Pineda-Urbina, Roberto Muniz-Valencia
Summary: The developed method offers a highly efficient way to quantify multiple emerging contaminants in water samples, with good quantitative results and high enrichment factors in a short total chromatographic time of 5.5 minutes.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Physical
Reza Hoseinpour Kouhestany, Atefeh Tamaddon, Homayon Ahmad Panahi, Arash Afshar Ebrahimi, Rahebeh Amiri
Summary: Researchers synthesized novel hyperbranched dendrimers grafted on SiO2 nanoparticles as nanosorbents for the trace extraction of exemestane. They optimized the parameters for adsorption efficiency and achieved a lower detection limit by using the HF-LPME system. The proposed method, combined with high-performance liquid chromatography, successfully determined exemestane in biological and pharmaceutical samples.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Environmental Sciences
Kiranmayi P. Mangalgiri, Temitope Ibitoye, Lee Blaney
Summary: This study employed enhanced spectrophotometric methods to determine the acid dissociation constants and molar absorption coefficients for certain antibiotics. Molar absorption coefficient heatmaps were generated for these antibiotics, revealing the influence of acid dissociation constants on their UV absorbance.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Instruments & Instrumentation
Qingsheng Bai, Yongguang Yin, Yanwanjing Liu, Haowen Jiang, Mengxin Wu, Weidong Wang, Zhiqiang Tan, Jingfu Liu, Myeong Hee Moon, Baoshan Xing
Summary: Due to the increased applications of engineered elemental metal nanoparticles (EMNPs) in recent years, their release into the environment has gained attention. The on-line coupling of flow field-flow fractionation with inductively coupled plasma mass spectrometry (F4-ICPMS) has been well established for the characterization of EMNPs in complex matrices of environmental samples. This review focuses on the specific advantages of the F4 method and recent advances in the application of F4-ICPMS techniques in examining the occurrence and transformation of EMNPs in the environment.
APPLIED SPECTROSCOPY REVIEWS
(2023)
Article
Environmental Sciences
Li Li, Su-Juan Yu, Rong-Gang Zheng, Peng Li, Qing-Cun Li, Jing-Fu Liu
Summary: The synthesized nanocomposite Ag-D201 showed high efficiency in removing iodide from water, and its adsorption capacity was influenced by pH and water matrix. The synergistic mechanism for iodide adsorption by Ag-D201 was proposed, including the Donnan membrane effect caused by D201 resin, chemisorption of iodide by AgNPs, and catalytic effect of AgNPs.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Environmental Sciences
Ruohua Qu, Mi Chen, Jingfu Liu, Qiting Xie, Na Liu, Fei Ge
Summary: Studies have shown that silver nanoparticles (AgNPs) have a negative impact on ATP generation of aquatic organisms, leading to decreased ATP content and metabolic disturbances. AgNPs compete with adenosine diphosphate and inorganic phosphate for binding sites on chloroplast ATPase, reducing substrate binding efficiency. Additionally, AgNPs significantly inhibit multiple ATP-related metabolic pathways. These findings are of great significance for understanding the mechanism of energy supply and metabolic regulation in aquatic organisms under nanoparticle stress.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Environmental Sciences
Sujuan Yu, Hao Liu, Rui Yang, Wenjing Zhou, Jingfu Liu
Summary: This study systematically investigated the aggregation and stability of selenium nanoparticles (SeNPs) under various water conditions using alginate-coated SeNPs (Alg-SeNPs) and polyvinyl alcohol-coated SeNPs (PVA-SeNPs) as models. The results showed that Alg-SeNPs underwent apparent aggregation in the presence of calcium and lanthanum ions, while PVA-SeNPs remained highly stable. Natural organic matter enhanced the stability of Alg-SeNPs in monovalent electrolytes but accelerated their attachment in polyvalent electrolytes. The long-term stability experiments demonstrated that both Alg-SeNPs and PVA-SeNPs increased in aggregation size over time, indicating their potential suspension or settling in water.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Engineering, Environmental
Zhimin Fan, Huachao Zhao, Kaifeng Wang, Wei Ran, Jie-Fang Sun, Jingfu Liu, Rui Liu
Summary: Electrochemical reduction (ER) is a promising method for pollutant removal, but its application is limited by slow reaction kinetics and side reactions. In this study, the role of interfacial hydrophilicity in determining ER performance was investigated. It was found that a hydrophobic Pd/C electrocatalyst hindered the diffusion of water and pollutants, leading to decreased mass transfer and decontamination efficiency. However, this dilemma could be overcome by increasing hydrophilicity with hydrophilic polymers, resulting in a significant improvement in the activity and efficiency of the electrocatalyst.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Yujian Lai, Lijie Dong, Xueying Sheng, Qingcun Li, Peng Li, Zhineng Hao, Sujuan Yu, Jingfu Liu
Summary: This study investigated the fate of polystyrene nanoparticles in real marine environments. The results showed that light irradiation promoted the aggregation process, and various transformations such as swelling, fragmentation, and polymer leaching were observed. The study also found that similar transformation processes occur for nanoparticles of different polymer types, which may be attributed to the penetration of ions in seawater.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Dibaba Bayana, Meseret Amde, Deribachew Bekana, Jingfu Liu
Summary: A colorimetric sensor based on silver nanoparticles was developed for the detection of Pb(II) ions. The sensor is simple, rapid, cost-effective, and environmentally friendly, and exhibits sensitivity and selectivity towards Pb(II). It showed high recovery rates in various real-world samples.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Qingsheng Bai, Qingcun Li, Jingfu Liu
Summary: We developed an effective method for determining the particle number, size, and species of dominant AgCNPs in soils. AgCNPs were extracted efficiently from soils using ultrasonication wand-assisted tetrasodium pyrophosphate extraction. Multistep selective dissolution of Ag NPs, AgCl NPs, and whole Ag NPs/AgCl NPs/Ag2S NPs was achieved by different reagents. The concentrations and sizes of AgCNPs in the extracts were determined, and Ag2S NPs were found to be the main form of AgCNPs in the soils.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Xiaoyu Zhao, Wei Ran, Zixuan Wang, Jiefang Sun, Rui Liu, Jingfu Liu
Summary: This article investigated the structural transformation of Pd shells on Au nanocubes in different electrolytes at various electrochemical windows. It was found that Pd sites are stable under basic and neutral conditions but experience severe structure evolution under acidic conditions. Pd atoms react with H+ under acidic conditions to form Pd ions, which are easily coreduced with Au ions into surface alloys.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Xiaotian Hua, Wenxuan Wang, Wei Ran, Guangzhi He, Jingfu Liu, Rui Liu
Summary: Metal nitrides, especially TiN, can effectively modulate the electronic states of Pd sites and enhance their catalytic performance in hydrodechlorination reactions, making them promising supports for highly efficient Pd catalysts.
Review
Biochemistry & Molecular Biology
Jing Wu, Yunwen Wang, Xuexin Gong, Mei He, Xiaoli Wang, Rusong Zhao, Zhineng Hao, Jingfu Liu
Summary: Halogenated organic compounds (HOCs) are widely found in environmental waters, but current analytical techniques cannot identify and quantify all individual HOCs. Total organic halogen (TOX) is proposed as a total quantity index for HOCs in waters, and significant progress has been made. This review presents an overview of TOX analysis, including detection and pretreatment methods, separation methods with and without enrichment, and key factors. It emphasizes the need for more efficient TOX measurement approaches in the future.
ENVIRONMENTAL POLLUTANTS AND BIOAVAILABILITY
(2023)
Article
Engineering, Environmental
Peng Li, Yujian Lai, Rong-gang Zheng, Qing-cun Li, Xueying Sheng, Sujuan Yu, Zhineng Hao, Ya-qi Cai, Jingfu Liu
Summary: A novel method combining TMAH digestion and DCM dissolution has been developed to extract small microplastics and nanoplastics embedded in soils, sediments, and sludges. The feasibility of this method has been verified and it shows promise for evaluating small solid-embedded microplastic and nanoplastic pollution.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Xue-ying Sheng, Yu-jian Lai, Su-juan Yu, Qing-cun Li, Qing-xiang Zhou, Jing-fu Liu
Summary: Plastic has been shown to release nanoparticles (NPs) into the atmosphere when exposed to sunlight, which poses a continuous health risk to the respiratory system. This study presents a simple and reliable method for quantifying atmospheric polystyrene (PS) NPs using pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS). The method demonstrated excellent reproducibility and high sensitivity, with a detection limit as low as 15 pg/m(3) for PS NPs. The method can be used for routine monitoring of atmospheric PS NPs and assessing their risk to human health.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Huachao Zhao, Wei Ran, Guangzhi He, Hongxin Wei, Jiefang Sun, Xiaoxia Zhou, Shiwei Li, Jingfu Liu, Bing Yan, Rui Liu, Guibin Jiang
Summary: Bond length is an important structural parameter that can affect the activity of catalysts. In core-shell gold-palladium (Au@Pd) nanocatalysts, elongated Pd-Pd bonds resulting from lattice mismatches between Au and Pd are found to exhibit distinct catalytic activity. Surface-enhanced Raman scattering (SERS) spectra of chemisorbed 2,6-dimethylphenyl isocyanide (2,6-DMPI) were used to investigate the elongated Pd-Pd bonds on Au@Pd. The study revealed that strained sites with elongated Pd bonds are more than 100 times more active in a catalyzed Suzuki-Miyaura coupling reaction.
Article
Chemistry, Multidisciplinary
Shiwei Li, Huachao Zhao, Wei Ran, Jingfu Liu, Rui Liu
Summary: Au@RhPd ultrathin nanowires serve as a highly reactive and selective catalyst for the hydrogenation of phenol at ambient conditions. The interaction between Au NWs and Rh atoms enhances the adsorption and desorption processes, while Pd acts as a cocatalyst to activate H2 and transfer it to Rh sites. This catalyst exhibits a turnover frequency of up to 560 h(-1) with over 80% selectivity towards cyclohexanones.
CHEMICAL COMMUNICATIONS
(2022)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)