Article
Optics
Hongnan Xu, Yue Qin, Gaolei Hu, Hon Ki Tsang
Summary: This paper presents a spectrometer design that surpasses the resolution-bandwidth limit, by tailoring the dispersion of mode splitting in a photonic molecule to identify spectral information at different free-spectral ranges (FSRs). Experimental results demonstrate that this approach can resolve arbitrary spectra with discrete, continuous, or hybrid features.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Review
Optics
Lichao Zhang, Jiamin Chen, Chaowei Ma, Wangzhe Li, Zhimei Qi, Ning Xue
Summary: Researchers have systematically reviewed the progress in on-chip FTSs, especially in on-chip static FTSs, focusing on theories, implementations, and performance indicators, to investigate the trade-off between reduced size and spectrometer performance.
LASER & PHOTONICS REVIEWS
(2021)
Article
Optics
Xiangzhe Zhang, Liqing Huang, Jingping Zhu, Ning Zhang, Kang Zong, Lipeng Zhai, Yu Zhang, Yakun Cai, Huimin Wang
Summary: The OPD equations of dual Wollaston prisms with an adjustable air gap are derived using the wave normal tracing method, and their validity is verified. The performance of a novel static birefringent Fourier transform imaging spectrometer based on these prisms is investigated.
Article
Biochemical Research Methods
Elvin R. Cabrera, Brian H. Clowers
Summary: This study describes a method of modulating the ion gates of ion mobility spectrometry using a discrete stepwise function, achieving synchronization between the generated frequencies and the scan rate of the linear ion trap. This method eliminates the ambiguity of assigning the ion current derived from a single modulation frequency and maintains high levels of precision across different combinations.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Optics
M. Capezzuto, D. D'Ambrosio, S. Avino, A. Giorgini, G. Gagliardi, P. Malara
Summary: In this study, a fast-scan optofluidic Fourier transform (FT) spectrometer on the tip of an optical fiber is demonstrated by stabilizing the evaporation dynamics of a microliter fluorocarbon droplet. Compared with other FT near-infrared (NIR) small-scale spectrometers reported in the literature, the fluorocarbon droplet spectrometer shows the largest wavelength span and span/resolution ratio, enabling easy spectral analysis of broadband or narrowband radiation. This opens up practical applications for droplet spectrometers as advanced optofluidic NIR analyzers with small size and low cost, capable of operating in harsh environments.
Article
Biochemical Research Methods
Elvin R. Cabrera, Brian H. Clowers
Summary: By casting ion population's mobility information in the frequency domain, time-dispersive ion mobility techniques can now be compatible with slower mass analyzers like ion traps. Recent progress has been made in maximizing the efficiency of Fourier transform ion mobility-mass spectrometry (FT-IM-MS) experiments, but the intersection between practical implementation considerations and theoretical limits of traditional signal processing techniques needs to be further explored. The importance of avoiding signal aliasing due to undersampling signals, along with evaluating limitations imposed by experimental parameters, is crucial for successful Fourier-based multiplexing experiments.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Immunology
Orsolya Tuende Kovacs, Eszter Toth, Oliver Ozohanics, Eszter Soltesz-Katona, Nikolett Marton, Edit Iren Buzas, Laszlo Hunyady, Laszlo Drahos, Gabor Turu, Gyorgy Nagy
Summary: This study investigated the proteomic changes during osteoclast differentiation in healthy donors, RA, and PsA. The results showed increased expression of proteins involved in metabolic activity, secretory function, and cell polarity during differentiation, while immune signaling pathways were downregulated. The expression differences between healthy donors and RA/PsA patients were most noticeable after the final steps of differentiation. The study provides important insights into the pathophysiology of RA and PsA.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Optics
Ang Li, Yeshaiahu Fainman
Summary: An ultra-high resolution Fourier transform spectrometer realized in a silicon photonic platform is reported, which can handle broad band, narrow band, as well as a combination of both signals. The high resolution is achieved by utilizing multiple techniques such as a Michelson interferometer structure, hybrid waveguide design, optimized heater, and air trenches. A novel multiple interferometers approach is employed to further increase the optical path delay of the spectrometer, leading to higher resolution.
LASER & PHOTONICS REVIEWS
(2021)
Article
Chemistry, Analytical
Wanzhen Han, Shiyu Du, Caowei Tang, Yiling Li, Ting Jiang, Wei Xu
Summary: The integration of a liquid-phase ion trap with a miniature mass spectrometer improves detection sensitivity and enables enrichment and separation of ions, making it suitable for the analysis of low abundant target molecules.
ANALYTICA CHIMICA ACTA
(2022)
Article
Optics
Chunlei Sun, Chuyu Zhong, Maoliang Wei, Hui Ma, Ye Luo, Zequn Chen, Renjie Tang, Jialing Jian, Hongtao Lin, Lan Li
Summary: An innovative optical filter with FSR-free operation capability, subnanometer optical bandwidth, and acceptable fabrication tolerance has been demonstrated, showing great potential for large-capacity optical transmission and multiparameter sensing applications. By appropriately designing a specific structure of filter unit, a single deep dip within a wide bandwidth can be observed, and multiple units can be cascaded to achieve a multichannel filter.
PHOTONICS RESEARCH
(2021)
Article
Chemistry, Analytical
Zhixiong Yang, Kun Li, Chunchao Yu, Mingyao Yuan, Boyang Wang, Jie Feng
Summary: A temporally and spatially modulated long-wave infrared (LWIR)-imaging Fourier transform spectrometer was used to achieve hyperspectral imaging. This method enables rapid detection of hazardous gas leakage, ensuring personal safety.
Article
Chemistry, Physical
Atul Verma, Yi-An Hong, Anren Hu, Yen-Pei Fu
Summary: Optimization of Cu2O morphology using NH4OH has rarely been explored. In this study, the influence of NH4OH on Cu2O morphology was investigated, and the spherical shape was transformed into octahedron-like octaspheres. The {100} facets at the corners of the Cu2O octaspheres could be etched. The morphology variations and facet etchings were studied using FESEM images and XRD analysis, showing a peak shift in Cu2O (111). Cu2O was then hybridized with rGO and g-C3N4 to form a ternary hybrid CGR, which effectively degraded the antibiotic pollutant tetracycline.
APPLIED SURFACE SCIENCE
(2023)
Article
Biochemical Research Methods
Leah Schaffer, Lissa C. Anderson, David S. Butcher, Michael R. Shortreed, Rachel M. Miller, Caitlin Pavelec, Lloyd M. Smith
Summary: Proteoform Suite software was used to analyze top-down proteomic data and construct proteoform families, successfully identifying a portion of proteoforms. This study provides a new method for high-accuracy protein identification.
JOURNAL OF PROTEOME RESEARCH
(2021)
Article
Optics
Qihang Chu, Xiaotian Li, Jirigalantu, Ci Sun, Jun Chen, Jianing Wang, Yuqi Sun, Bayanheshig
Summary: This paper presents a cross-dispersed spatial heterodyne spectrometer (CDSHS) that combines a spatial heterodyne spectrometer (SHS), a reflection grating, and a cylindrical lens. It provides expressions for the width, height, and location of the cross-dispersed interferograms corresponding to narrow spectral regions. A design example of CDSHS, including numerical simulations of the interferogram and the spectrum, is provided to illustrate the system. The results demonstrate that the CDSHS can simultaneously disperse different narrow spectral regions and obtain detailed spectra independently with a high signal-to-noise ratio, while maintaining advantages such as high resolution, high throughput, compactness, and zero moving parts. The CDSHS has great potential in applications such as multiple spectral feature measurement and weak spectral measurements.
Review
Chemistry, Multidisciplinary
Chang Li, Shiying Chu, Siyuan Tan, Xinchi Yin, You Jiang, Xinhua Dai, Xiaoyun Gong, Xiang Fang, Di Tian
Summary: This review discusses the latest developments in mass analyzers to improve the sensitivity of mass spectrometers. The advantages and limitations of different mass analyzers and their combinations are compared and discussed. It provides guidance for the selection of suitable mass spectrometers in chemical and biological analytical applications.
FRONTIERS IN CHEMISTRY
(2021)
Correction
Biochemical Research Methods
Yong Wang, Suhua Yu, Rui Li, Jing Wan, Yuheng Wang, Zongli Huo, Chunyong Wu, Li Mi, Songqin Liu
JOURNAL OF CHROMATOGRAPHY A
(2024)
Review
Biochemical Research Methods
Israel D. Souza, Maria Eugenia C. Queiroz
Summary: Organic-silica hybrid monolithic materials have gained significant attention in separation science and sample preparation due to their unique properties. This review summarizes the characteristics, current status, and recent developments of these materials, as well as discusses synthesis methods, characterization techniques, and strategies for improving extraction efficiency in various applications.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Bhagwat Upreti, Bhanu Prasad Vempatapu, Jagdish Kumar, Pankaj K. Kanaujia
Summary: Lubricating oils are essential for the effective performance of internal combustion engines. This study presents a new HPLC method for determining additives in finished lubricating oils and polar substances in used engine oils.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zongqing Huang, Haoju Hua, Xiuzhen Du, Zipeng Zhen, Wei Zhao, Jun Feng, Ji-an Li
Summary: This study successfully isolated VHHs against the SUMO protein for the first time using biopanning of an immune camelid nanobody library. The VHHs were coupled to agarose resins to form affinity chromatography resins, allowing for one-step purification of various SUMO fusions.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Xueting Qiu, Xuben Hou, Yue Yang, Hao Fang, Fei Cui, Xinying Yang
Summary: In this study, a new method based on electrophoretically mediated microanalysis was developed for the investigation of PTPRO enzymatic activity. The method was successfully used to determine the kinetics of PTPRO and the inhibitory concentration of PTPRO inhibitors. The method exhibited improved accuracy and reduced consumption compared to traditional methods.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Feifei Luo, Mengmeng Hao, Lei Zhang, Yangguo Xie, Wei Hou, Hongya Wang, Zhongli Zhang
Summary: In this study, a comprehensive screening and structure elucidation of 23 nonvolatile organic compounds (NVOCs) in two antibody drugs was conducted. Seven previously unreported compounds were identified. A quantitative method with high sensitivity, accuracy, and precision was developed for evaluating the safety of NVOCs in drug products.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zuzana Vosahlova, Kveta Kalfkova, Martin Gilar, Jakub Szymarek, Maria Mazurkiewicz-Beldzinska, Sylwia Studzi
Summary: A hydrophilic interaction liquid chromatography method was developed for the separation and identification of oligonucleotide impurities and metabolites, and successfully applied to the analysis of serum samples from Spinraza-treated patients.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Aswanidevi Kongasseri, Thirumalai Madhesan, Sangeetha Krishna Kumar, Sushmitha Pedugu Sivaraman, Suchashrita Mitra, Pitchaiah Kancharlapalli Chinaraga, C. V. S. Brahmmananda Rao, Sivaraman Nagarajan, Prabhakaran Deivasigamani, Akhila Maheswari Mohan
Summary: This study focuses on the sequential separation of trivalent lanthanides using modified C-18 silica-packed supports and reversed-phase HPLC technique. By tuning the column modifiers and separation parameters, the researchers achieved systematic separation of Ln(3+). The results showed that the choice of column modifiers and fine-tuning of the modification procedure were crucial for achieving excellent separation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Raquel Perez-Robles, Szabolcs Fekete, Robert Kormany, Natalia Navas, Davy Guillarme
Summary: There is a mismatch between the sample diluent and the mobile phase in HILIC analysis, leading to analyte breakthrough and peak distortion. Adding a weak solvent for pre-injection can effectively prevent these issues and improve sensitivity.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oleg Pokrovskiy, Irina Rostovschikova, Konstantin Ustinovich, Ilya Voronov, Dmitry Kosyakov
Summary: A chromatography-like propagation of water through the material bed was observed during supercritical fluid extraction of aroma plants with high moisture content, which could be significant for modeling the kinetics of supercritical fluid extraction of non-volatile compounds.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Yasar Kemal Recepoglu, Ozguer Arar, Asli Yuksel
Summary: Biosorption using phosphorylated hazelnut shell waste (FHS) is a promising method for lithium removal and recovery. This study investigated the performance of a continuous-flow packed-bed column system using FHS for ultra-low level lithium removal. The results showed that the lihium biosorption capacity of the FHS column was unaffected by the bed height, but decreased with increasing flow rate.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Jian Sun, Zheheng Zheng, Zixiao Jia, Jiabin Wang, Xucong Lin
Summary: In this study, an ionic covalent organic framework (iCOF) surface grafting monolithic sorbent was prepared for in-tube solid-phase microextraction (SPME) of aristolochic acids (AAs) in various samples. The density of quaternary ammonium ions in the iCOF was modulated for enhanced adsorption of AAs. The iCOF surface grafting monolithic sorbent was confirmed by different means. Several operating conditions were optimized to develop the online in-tube SPME-HPLC method, which showed good linearity, low limits of detection, and high recoveries for AAs in serum samples. This study presents a feasible approach for the application of COF-based monolithic sorbents in sample preparation.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Zeng Wen, Ruihan Peng, Die Gao, Jing Lin, Jia Zeng, Zhou Li, Famin Ke, Zhining Xia, Dandan Wang
Summary: A chitosan-alginate sponge with multiple cross-linking networks was developed for adsorption and enrichment of anionic dyes from food samples. The sponge showed better three-dimensional network structure, mechanical behavior, and stability compared to pure chitosan and alginate sponges. The adsorption performance and selectivity of the sponge were systematically studied, and it maintained high adsorption capacity and selectivity for anionic dyes. The sponge also showed satisfactory reusability and was successfully combined with high-performance liquid chromatography for the enrichment and detection of anionic dyes in candy and cocktail samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Hairong Zhang, Xiaojuan Jiang, Dandan Zhang, Yuexin Yang, Qiang Xie, Caisheng Wu
Summary: Analysis of in vivo exposure to traditional Chinese medicine using mass spectrometry is helpful for identifying effective ingredients and developing new drugs. This study focused on Forsythia suspensa (Lian Qiao) and used metabolomics technology to explore its in vivo exposure. By comparing the differences before and after administration, a complete set of nontargeted analysis strategies for TCM exposure was established. The study identified 393 Lian Qiao-related chemical components in mice after administration, including prototypes and metabolites. This study provides a reference for research on the active ingredients of Lian Qiao in vivo.
JOURNAL OF CHROMATOGRAPHY A
(2024)
Article
Biochemical Research Methods
Oscar Castejon-Musulen, Ricardo Lopez, Ignacio Ontan, Vicente Ferreira
Summary: A quantitative analytical method was developed and validated in this study to determine the concentrations of 81 aroma-relevant wine volatiles. The method utilizes stir bar sorptive extraction and multidimensional gas chromatography with flame ionization detector or mass spectrometer. The method demonstrated good linearity, reproducibility, and recovery, and was successfully applied to analyze 20 wine samples.
JOURNAL OF CHROMATOGRAPHY A
(2024)