4.1 Article Proceedings Paper

The Presence of Attention-Deficit Hyperactivity Disorder (ADHD) and Obsessive-Compulsive Disorder Worsen Psychosocial and Educational Problems in Tourette Syndrome

期刊

JOURNAL OF CHILD NEUROLOGY
卷 25, 期 2, 页码 171-181

出版社

SAGE PUBLICATIONS INC
DOI: 10.1177/0883073809336215

关键词

Tourette syndrome; psychosocial consequences; comorbidity; ADHD

向作者/读者索取更多资源

We assessed the psychosocial and educational consequences of Tourette syndrome using a structured interview and child behavior checklist in 314 children with Tourette syndrome and 81 healthy controls. Of the children with Tourette syndrome, 59.0% needed some kind of educational support, 44.7% had been teased, and 61.8% withheld themselves from taking part in social activities because of Tourette syndrome-related problems. There were significantly more psychosocial and educational problems in children with Tourette syndrome compared with healthy controls. A higher rate of these problems was also seen if the comorbidities attention-deficit hyperactivity disorder (ADHD) and/or obsessive compulsive disorder were present. It is very important for the physicians, teachers, and other professionals to be aware of the high prevalence of these social and educational problems to be able to deal with them and to teach the families to cope with them.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.1
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Review Psychology, Developmental

European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part II: psychological interventions

Per Andren, Ewgeni Jakubovski, Tara L. Murphy, Katrin Woitecki, Zsanett Tarnok, Sharon Zimmerman-Brenner, Jolande van de Griendt, Nanette Mol Debes, Paula Viefhaus, Sally Robinson, Veit Roessner, Christos Ganos, Natalia Szejko, Kirsten R. Mueller-Vahl, Danielle Cath, Andreas Hartmann, Cara Verdellen

Summary: Part II of the European clinical guidelines for Tourette syndrome and other tic disorders provides updated information and recommendations for psychological interventions, recommending Habit Reversal Training (HRT) and Exposure and Response Prevention (ERP) as first-line interventions for tic disorders. Cognitive interventions and third-wave interventions are currently not recommended as stand-alone treatments for tic disorders.

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY (2022)

Review Psychology, Developmental

European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part III: pharmacological treatment

Veit Roessner, Heike Eichele, Jeremy S. Stern, Liselotte Skov, Renata Rizzo, Nanette Mol Debes, Peter Nagy, Andrea E. Cavanna, Cristiano Termine, Christos Ganos, Alexander Muenchau, Natalia Szejko, Danielle Cath, Kirsten R. Mueller-Vahl, Cara Verdellen, Andreas Hartmann, Aribert Rothenberger, Pieter J. Hoekstra, Kerstin J. Plessen

Summary: The first European guidelines for Tourette Syndrome (TS) were published in 2011 by the European Society for the Study of Tourette Syndrome (ESSTS). The updated part on pharmacological treatment emphasizes the importance of psychoeducation and behavioral approaches as first-line treatments. Pharmacological treatment, particularly with dopamine blocking agents like aripiprazole, is indicated in some patients, especially when behavioral approaches are not effective or feasible. Treatment should be individualized based on the patient's needs, preferences, and co-existing conditions.

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY (2022)

Review Psychology, Developmental

European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part I: assessment

Natalia Szejko, Sally Robinson, Andreas Hartmann, Christos Ganos, Nanette M. Debes, Liselotte Skov, Martina Haas, Renata Rizzo, Jeremy Stern, Alexander Munchau, Virginie Czernecki, Andrea Dietrich, Tara L. Murphy, Davide Martino, Zsanett Tarnok, Tammy Hedderly, Kirsten R. Muller-Vahl, Danielle C. Cath

Summary: This article presents an updated version 2.0 of European clinical guidelines for Tourette syndrome and other tic disorders, focusing on assessment. The guidelines were developed through thorough literature screening, national guidelines supplementation, and expert discussions within ESSTS. Diagnostic changes between DSM-IV and DSM-5 classifications, recommendations for rating scales, and new information on differential diagnoses are highlighted. Additionally, a recent survey among ESSTS members on assessment in TS is discussed.

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY (2022)

Article Psychiatry

Concordance and comorbidities among monozygotic twins with tic disorders

Julie Holst Pedersen, Axel Skytthe, Jonas Bybjerg-Grauholm, Asli Sena Kucukyildiz, Liselotte Skov, Nanette Mol Debes, Zeynep Tumer

Summary: Gilles de la Tourette Syndrome (GTS) is a multifactorial neurodevelopmental disorder characterized by tics and multiple comorbidities. Twin studies indicate that both genetic and environmental risk factors are involved. The study found high concordance of GTS and chronic tic disorders in monozygotic twins, suggesting common genetic risk factors. The findings also showed higher comorbidity rates in twins with GTS or CTD compared to the general population.

JOURNAL OF PSYCHIATRIC RESEARCH (2022)

Article Clinical Neurology

Headache in Children and Adolescents: The Association between Screen Time and Headache within a Clinical Headache Population

Josefine Lund, Amalie Berring-Uldum, Merve Colak, Nanette Marinette Monique Debes

Summary: The study showed an association between screen time and headache frequency in children and adolescents, especially in those with migraine with aura. However, there was no statistically significant difference in total screen time across the five headache groups. Future prospective studies are needed to determine causality in this association.

NEUROPEDIATRICS (2022)

Review Clinical Neurology

Migraine Pathophysiology in Children and Adolescents: A Review of the Literature

Astrid Forland-Schill, Amalie Berring-Uldum, Nanette Mol Debes

Summary: This review aims to describe the pathophysiological characteristics of migraine in pediatric patients and discuss the possible differences with adult migraine, as well as the need for further research on pediatric patients with migraine.

JOURNAL OF CHILD NEUROLOGY (2022)

Article Clinical Neurology

Impact of Tourette Syndrome on Education

Josefine Lund, Liv Borch-Johnsen, Camilla Groth, Liselotte Skov, Nanette Mol Debes

Summary: This study investigated the association between the severity of tics and comorbidities and educational outcomes in Tourette syndrome (TS) patients. It was found that children with TS had a lower passing rate at lower secondary school and high school compared to healthy controls. The severity of comorbidities was more likely to drive this difference than tic severity. Therefore, it is important to provide the right support for children with TS in order to optimize their educational opportunities.

NEUROPEDIATRICS (2023)

Article Clinical Neurology

Exposure and Response Prevention: Evaluation of Tic Severity Over Time for Children and Adolescents with Tourette Syndrome and Chronic Tic Disorders

Camilla Birgitte Soerensen, Theis Lange, Sidsel Normann Jensen, Judy Grejsen, Lone Aaslet, Liselotte Skov, Nanette Mol Debes

Summary: Tourette syndrome and chronic tic disorders are characterized by tics. Although different behavioral therapies have been effective in treating tics in children and adolescents, Exposure and Response Prevention (ERP) has not been extensively studied. This study evaluated the long-term effects of ERP on tic severity and found that it had a significant and lasting effect, particularly for those who completed the program or discontinued due to positive results.

NEUROPEDIATRICS (2023)

Article Clinical Neurology

Exposure and Response Prevention for Children and Adolescents with Tourette Syndrome Delivered via Web-Based Videoconference versus Face-to-Face Method

Camilla Birgitte Soerensen, Theis Lange, Sidsel Normann Jensen, Judy Grejsen, Lone Aaslet, Liselotte Skov, Nanette Mol Debes

Summary: Chronic tic disorders, such as Tourette syndrome, can be effectively treated using a behavioral therapy called exposure and response prevention (ERP). However, limited treatment sites hinder access to this therapy. Web-based videoconferences offer a solution by connecting patients at home with therapists in hospitals, providing treatment over a wide geographic area. In this study, ERP delivered via web-based videoconferences was found to be as effective as the traditional face-to-face method.

NEUROPEDIATRICS (2023)

Article Clinical Neurology

Increased Number of Functional Tics Seen in Danish Adolescents during the COVID-19 Pandemic

Kirstine Birkebaek Okkels, Liselotte Skov, Susanne Klanso, Lone Aaslet, Judy Grejsen, Annika Reenberg, Camilla Birgitte Sorensen, Nanette Marinette Monique Mol Debes

Summary: The study investigates the possible triggers for the development of functional tics in adolescents and discusses the role of the COVID-19 pandemic and social media exposure in these cases. The treatment for functional tics includes psychoeducation, cognitive behavioral therapy, and focusing on psychiatric symptoms, with positive responses from all patients.

NEUROPEDIATRICS (2023)

Article Health Care Sciences & Services

Clarifying the Differences between Patients with Organic Tics and Functional Tic-Like Behaviors

Kaja Andersen, Ida Jensen, Kirstine Birkebaek Okkels, Liselotte Skov, Nanette Mol Debes

Summary: Due to an increase in the number of patients with Functional Tic-Like Behaviors (FTLB), it is important to find differences between this patient group and patients with organic tics (OTs) for accurate diagnosis. This retrospective study examined established and suggested differences between the groups, replicating some findings from literature and revealing new differences. The study highlighted that FTLB patients have more complex tics, older symptom onset age, higher female representation, and fewer family members with tics compared to OT patients. Additionally, FTLB patients have more family members with psychiatric disorders, are more likely to experience adverse psychosocial events before symptom onset, and have fewer simple tics.

HEALTHCARE (2023)

Article Clinical Neurology

Decreased Cognitive Function in Danish Children with Epilepsy

Laura Bogut, Kaja Andersen, Judy Grejsen, Maria Jose Miranda Gimenez-Rico, Nanette Monique Mol Debes

Summary: The cognitive function of healthy Danish children and Danish children diagnosed with epilepsy was examined using EpiTrack Junior. The patient group showed significantly lower test scores compared to the control group, confirming the relationship between impaired cognitive function and childhood epilepsy. Furthermore, there was a correlation between a higher EpiTrack Junior score and the presence of generalized tonic-clonic seizures (GTCS), while focal seizures and antiepileptic drug treatment were not associated with the EpiTrack Junior score.

NEUROPEDIATRICS (2023)

Article Clinical Neurology

Childhood Comorbidity Severity Impacts Adolescent Substance Consumption in Patients With Tourette Syndrome

Kaja Andersen, Camilla Groth, Liselotte Skov, Nanette Mol Debes

Summary: This study examines the longitudinal impact of Tourette Syndrome (TS) severity, Attention-Deficit/Hyperactivity Disorder (ADHD) and Obsessive-Compulsive Disorder (OCD) diagnosis and severity, and guardian socioeconomic status on substance use in pediatric patients with TS. The results indicate that greater severity of ADHD and lower guardian socioeconomic status significantly increase the likelihood of higher cigarette consumption in the future. Additionally, the presence and increased severity of ADHD at baseline increase the odds of illegal substance consumption later on, while increased severity of OCD at baseline decreases cigarette and illegal substance consumption, and presence and increased severity of OCD decrease alcohol consumption. Preventative conversations about substance use are crucial for pediatric patients with TS and high ADHD severity.

PEDIATRIC NEUROLOGY (2023)

Article Psychiatry

Fine Motor Skills in Children with Tourette Syndrome and their Unaffected First-degree Siblings

Marie Louise Boeg Tygesen, Katrine Maigaard, Julie Hagstrom, Liselotte Skov, Kerstin Jessica Plessen, Nanette Marinette Monique Debes

Summary: This study compared fine motor skill performance on the Purdue Pegboard Task (PPT) in 18 children with TS, 24 unaffected first-degree siblings and 20 controls. The results showed no significant differences in fine motor skills between children with TS, their siblings, and controls. However, there was an inverse correlation between performance on the PPT and the severity of ADHD symptoms, indicating that fine motor skill impairment in children with TS may be more strongly correlated with comorbid ADHD than to TS and tics. Evaluation: 8 out of 10.

SCANDINAVIAN JOURNAL OF CHILD AND ADOLESCENT PSYCHIATRY AND PSYCHOLOGY (2023)

Meeting Abstract Biochemistry & Molecular Biology

Elevated expression of SLC6A4 encoding the serotonin transporter (SERT) in Gilles de la Tourette syndrome

Amanda M. Levy, Mathis Hildonen, Christina Dahl, Victoria A. Bjerregaard, Lisbeth Birk Moller, Per Guldberg, Nanette M. Debes, Zeynep Tumer

EUROPEAN JOURNAL OF HUMAN GENETICS (2022)

暂无数据