Article
Multidisciplinary Sciences
Saartje Hontelez, Tim Stobernack, Lidy M. Pelsser, Peter van Baarlen, Klaas Frankena, Martine M. Groefsema, Michiel Kleerebezem, Rob Rodrigues Pereira, Elbrich M. Postma, Paul A. M. Smeets, Marion A. Stopyra, Marcel P. Zwiers, Esther Aarts
Summary: Research shows that a few-foods diet can substantially decrease ADHD symptoms in 60% of children, but the underlying mechanism is still unknown. A study found that changes in brain activation in certain regions were not associated with ADHD symptom change, while increased activation in the precuneus was correlated with decreased ADHD symptoms.
SCIENTIFIC REPORTS
(2021)
Review
Medicine, General & Internal
Margherita Barbuti, Marco Maiello, Vincenza Spera, Alessandro Pallucchini, Giulio E. Brancati, Angelo G. I. Maremmani, Giulio Perugi, Icro Maremmani
Summary: Adults with ADHD often have comorbid substance use disorder (SUD), leading to greater severity of both disorders and additional challenges for treatment. Current research on pharmacological management of ADHD with comorbid SUD is limited, particularly in regards to the long-term effects of stimulant medications on dopamine signaling. Evidence suggests that high doses of stimulant medications have moderate efficacy on ADHD symptoms in ADHD-SUD subjects, but there is a risk for misuse. Atomoxetine is recommended for ADHD with comorbid cocaine or amphetamine use disorder, but its effectiveness in reducing addictive behavior is not well-demonstrated. For other subtypes of SUD, both atomoxetine and stimulant drugs have limited impact on addictive behavior, and a combination of ADHD treatment and SUD-specific strategies is recommended.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Grace Mengqin Ge, Edmund C. L. Cheung, Kenneth K. C. Man, Patrick Ip, Wing Cheong Leung, Gloria H. Y. Li, Annie W. C. Kung, Ching-Lung Cheung, Ian C. K. Wong
Summary: The study found that maternal levothyroxine treatment during pregnancy is associated with an increased risk of preterm birth in offspring, but not significantly associated with low birth weight, ADHD, or ASD.
Article
Psychiatry
Benjamin MacDonald, Joseph Sadek
Summary: The study found that ADHD patients with SUD had more severe cognitive impairments and poorer functional outcomes at the time of diagnosis. The correlation with poorer ADHD outcomes was more pronounced in groups allocated based on heavy cannabis use status, which was associated with lower cognitive test scores and more severe hyperactivity and impulsivity.
Article
Multidisciplinary Sciences
Kristine Kaalund-Brok, Tine Bodil Houmann, Marie Bang Hebsgaard, Maj-Britt Glenn Lauritsen, Louise Hyldborg Lundstrom, Helene Gronning, Lise Darling, Susanna Reinert-Petersen, Morten Aagaard Petersen, Jens Richardt Mollegaard Jepsen, Anne Katrine Pagsberg, Kerstin Jessica Plessen, Henrik Berg Rasmussen, Pia Jeppesen
Summary: Randomized placebo-controlled trials have shown the efficacy of methylphenidate (MPH) for ADHD, but selection biases may limit generalizability. A study on 207 children with ADHD found that 81.2% responded favorably to carefully titrated MPH treatment with minimal adverse effects.
Article
Pediatrics
Christine Strand Bachmann, Kari Risnes, Johan Hakon Bjorngaard, Jorun Schei, Kristine Pape
Summary: The study examines the impact of relative age on mental health, specifically in preterm infants. The results show that being relatively young within a school class is associated with an increased likelihood of psychostimulant prescription, and this effect persists into young adulthood for preterm individuals.
Article
Psychology, Multidisciplinary
Morgan M. Grotewiel, Megan E. Crenshaw, Amelia Dorsey, Elizabeth Street
Summary: Hyperfocus and flow are intense concentration experiences associated with reduced perception of irrelevant stimuli and improved task performance. Hyperfocus has been historically seen as a symptom of ADHD, autism, or schizophrenia, while flow is regarded as an enjoyable experience in positive psychology. Recent studies suggest that hyperfocus and flow may be the same phenomenon viewed from different perspectives.
CURRENT PSYCHOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Hongtong Chen, Yichen Yan, Cong Li, Xiangyu Zheng, Guanghai Wang, Zhijuan Jin, Guocheng Shi, Xiaomin He, Xiaoping Tong, Huiwen Chen, Zhongqun Zhu
Summary: This study investigated the prevalence of attention-deficit/hyperactivity disorder symptoms (ADHD-like symptoms) and associated risk factors in children and adolescents with d-transposition of the great artery (D-TGA) who underwent arterial switch operation (ASO). The results showed that preoperative hypoxic status and delayed sternal closure were major risk factors for ADHD-like symptoms.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Multidisciplinary Sciences
Hsin-Yi Fan, Cheuk-Kwan Sun, Yu-Shian Cheng, Weilun Chung, Ruu-Fen Tzang, Hsien-Jane Chiu, Chun-Ning Ho, Kuo-Chuan Hung
Summary: This study provides a systematic review and analysis of the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) in treating the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults. The results suggest that EEG-NF can effectively improve inattention symptoms, but its effectiveness in reducing hyperactivity/impulsivity remains inconclusive.
SCIENTIFIC REPORTS
(2022)
Article
Psychology, Developmental
Margaret D. Weiss, Ann C. Childress, Graeme A. E. Donnelly
Summary: PRC-063 demonstrated good tolerability and significant improvement in ADHD symptoms in adults, with a notable impact on symptom reduction. There was no significant impact on sleep quality.
JOURNAL OF ATTENTION DISORDERS
(2021)
Editorial Material
Psychology, Developmental
Traci M. Kennedy, Brooke S. G. Molina
Summary: In their recent examination of the Monitoring the Future (MTF) data, McCabe et al. (Journal of Child Psychology and Psychiatry, 2023) investigate the relationship between stimulant medication treatment for adolescents with ADHD and their risk for substance use. Their nuanced findings suggest an increased risk for illicit stimulant use and non-prescribed stimulant medication use in youth who initiate treatment later and have shorter treatment duration. The authors highlight the clinical implications and recommend further research to clarify this important issue.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Correction
Biochemistry & Molecular Biology
Maria Soler Artigas, Cristina Sanchez-Mora, Paula Rovira, Vanesa Richarte, Iris Garcia-Martinez, Mireia Pagerols, Ditte Demontis, Sven Stringer, Jacqueline M. Vink, Anders D. Borglum, Benjamin M. Neale, Barbara Franke, Stephen V. Faraone, Miguel Casas, Josep Antoni Ramos-Quiroga, Marta Ribases
Summary: A correction to the paper has been published.
MOLECULAR PSYCHIATRY
(2021)
Article
Psychiatry
Dara E. Babinski, Erika F. H. Saunders, Fan He, Duanping Liao, Amanda M. Pearl, Daniel A. Waschbusch
Summary: This study examined the diagnostic indicators, clinical characteristics, and functional impairment associated with adult ADHD using electronic medical records and self-report measures. The results showed a significant difference in prevalence of ADHD between self-report screening and medical records. ADHD was found to contribute to functional impairment even when controlling for other psychiatric comorbidities.
PSYCHIATRY RESEARCH
(2022)
Article
Psychiatry
Daisuke Kikuchi, Taku Obara, Misaki Tokunaga, Makoto Shiozawa, Ai Takahashi, Misato Ito, Hiroaki Hino, Ryosuke Miura, Sachiko Hayakawa, Yoshiteru Watanabe
Summary: The study revealed changes in prescription trends of ADHD medications for pediatric outpatients in Japan from 2012 to 2018, with a decrease in the prescription rates of methylphenidate-OROS and atomoxetine, while an increase in the prescription rate of guanfacine.
ASIAN JOURNAL OF PSYCHIATRY
(2021)
Review
Biochemistry & Molecular Biology
E. M. Bruxel, C. R. Moreira-Maia, G. C. Akutagava-Martins, T. P. Quinn, M. Klein, B. Franke, M. Ribases, P. Rovira, C. Sanchez-Mora, D. B. Kappel, N. R. Mota, E. H. Grevet, C. H. D. Bau, M. Arcos-Burgos, L. A. Rohde, M. H. Hutz
Summary: This study conducted a meta-analysis to investigate the association between ADGRL3 gene variants and ADHD susceptibility in children and adults, finding significant correlation in children but not in adults. The results suggest that ADGRL3 gene is predominantly associated with childhood ADHD.
MOLECULAR PSYCHIATRY
(2021)