Article
Psychology, Multidisciplinary
Erica D. Musser, Stephanie S. J. Morris, Kathleen Feeney, Rosario Pintos Lobo, Edward F. Ester
Summary: Inattention is a key symptom of ADHD, but the mechanisms underlying it are unclear. More specific approaches are needed to link disruptions in cognitive performance with ADHD behaviors. A pilot study found that even typically developing children did not maximally extract and combine information to maximize rewards in a cognitive task targeting attention selection mechanisms.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Medicine, General & Internal
Nadia Ali, Amanda Caceres, Eric W. Hall, Dawn Laney
Summary: This pilot study compared reported symptoms of attention-deficit/hyperactivity in adults with Fabry disease with normative control data, finding a higher prevalence of symptoms in Fabry disease patients. The study suggests that attention difficulties in Fabry disease patients are not solely explained by ADHD. Patients reporting symptoms were also more likely to report difficulties in adaptive functioning.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Hsin-Yi Fan, Cheuk-Kwan Sun, Yu-Shian Cheng, Weilun Chung, Ruu-Fen Tzang, Hsien-Jane Chiu, Chun-Ning Ho, Kuo-Chuan Hung
Summary: This study provides a systematic review and analysis of the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) in treating the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults. The results suggest that EEG-NF can effectively improve inattention symptoms, but its effectiveness in reducing hyperactivity/impulsivity remains inconclusive.
SCIENTIFIC REPORTS
(2022)
Review
Biochemistry & Molecular Biology
Stephen Faraone, Jeffrey H. Newcorn, Andrea Cipriani, Daniel Brandeis, Anna Kaiser, Sarah Hohmann, Alexander Haege, Samuele Cortese
Summary: The study analyzed the placebo and nocebo effects in ADHD medications, finding significant impact of placebo effects on efficacy and negative effects on tolerability. It also discovered a positive correlation between baseline to endpoint placebo effects and drug effects.
MOLECULAR PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Sneha M. Vaddadi, Nicholas J. Czelatka, Belsy D. Gutierrez, Bhumika C. Maddineni, Kenneth L. McCall, Brian J. Piper
Summary: In recent years, the use of prescription stimulants in the United States has been increasing, particularly for amphetamine and lisdexamfetamine. The study found that the usage of stimulants in the Western region was lower compared to other regions, and areas with a higher percentage of Hispanic populations also had lower stimulant usage.
Review
Food Science & Technology
Sepide Talebi, Maryam Miraghajani, Abed Ghavami, Hamed Mohammadi
Summary: The study found that zinc supplementation may have beneficial effects in improving symptoms of ADHD in children. However, more well-designed, large-scale randomized controlled trials are needed to establish the benefit of zinc supplementation for ADHD. The certainty of the evidence was rated moderate to very low for all outcomes.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Psychology, Developmental
Karen Vertessen, Marjolein Luman, James M. Swanson, Marco Bottelier, Reino Stoffelsen, Pierre Bet, Annemiek Wisse, Jos W. R. Twisk, Jaap Oosterlaan
Summary: Methylphenidate (MPH) has been proven effective in treating ADHD symptoms in children. However, the relationship between dosage and symptom control varies greatly among individuals and the placebo effect also plays a role.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychiatry
Noemi Faedda, Cecilia Guariglia, Laura Piccardi, Giulia Natalucci, Serena Rossetti, Valentina Baglioni, Danilo Alunni Fegatelli, Maria Romani, Miriam Vigliante, Vincenzo Guidetti
Summary: This study compared the topographic memory abilities of children with ADHD-C and TD, finding that children with ADHD-C showed higher impairments in the WalCT test, particularly in tasks related to topographic short-term memory and learning, as well as in the repetition number task. Perseverative errors were observed during the square-sequence task.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Chemistry, Medicinal
Cheng-Dien Hsu, Li-Hsuan Hsieh, Ya-Ling Chen, I-Cheng Lin, Ying-Ru Chen, Chih-Chi Chen, Hitoshi Shirakawa, Suh-Ching Yang
Summary: The study investigated the effects of polyphenolic compounds from pine bark extract (PE) on inattention and impulsivity in children with ADHD. PE supplementation significantly reduced ADHD symptoms and improved antioxidative status. This suggests that PE supplementation may have potential benefits in ameliorating symptoms and enhancing antioxidative status in children with ADHD.
PHYTOTHERAPY RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
E. M. Bruxel, C. R. Moreira-Maia, G. C. Akutagava-Martins, T. P. Quinn, M. Klein, B. Franke, M. Ribases, P. Rovira, C. Sanchez-Mora, D. B. Kappel, N. R. Mota, E. H. Grevet, C. H. D. Bau, M. Arcos-Burgos, L. A. Rohde, M. H. Hutz
Summary: This study conducted a meta-analysis to investigate the association between ADGRL3 gene variants and ADHD susceptibility in children and adults, finding significant correlation in children but not in adults. The results suggest that ADGRL3 gene is predominantly associated with childhood ADHD.
MOLECULAR PSYCHIATRY
(2021)
Article
Pediatrics
Luisa Shiguemi Sugaya, Giovanni Abrahao Salum, Wagner de Sousa Gurgel, Erika Mendonca de Morais, Giovana Del Prette, Caroline Drehmer Pilatti, Bianca Batista Dalmaso, Ellen Leibenluft, Luis Augusto Rohde, Guilherme Vanoni Polanczyk
Summary: This study found that methylphenidate and behavioral parent training have significant effects in reducing symptoms and improving functionality for preschool children aged 3-5 with ADHD after 8 weeks of treatment.
LANCET CHILD & ADOLESCENT HEALTH
(2022)
Article
Health Care Sciences & Services
Antonella Gambadauro, Simone Foti Randazzese, Arianna Curro, Francesca Galletta, Giuseppe Crisafulli, Lucia Caminiti, Eva Germano, Gabriella Di Rosa, Antonio Gennaro Nicotera, Sara Manti
Summary: This study aimed to analyze therapeutic adherence in patients with attention deficit hyperactivity disorder (ADHD) and allergic rhinitis (AR) and estimate the impact of adherence on ADHD symptoms. The results showed a negative correlation between therapeutic adherence and AR symptoms as well as ADHD scores. Better adherence to AR therapy was associated with a reduction in inattention symptoms in children with ADHD.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Psychiatry
Dara E. Babinski, Erika F. H. Saunders, Fan He, Duanping Liao, Amanda M. Pearl, Daniel A. Waschbusch
Summary: This study examined the diagnostic indicators, clinical characteristics, and functional impairment associated with adult ADHD using electronic medical records and self-report measures. The results showed a significant difference in prevalence of ADHD between self-report screening and medical records. ADHD was found to contribute to functional impairment even when controlling for other psychiatric comorbidities.
PSYCHIATRY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Mia Moses, Jeggan Tiego, Ditte Demontis, G. Bragi Walters, Hreinn Stefansson, Kari Stefansson, Anders D. Borglum, Aurina Arnatkeviciute, Mark A. Bellgrove
Summary: This study examined three potential endophenotypes for attention-deficit hyperactivity disorder (ADHD): working memory function, response inhibition, and reaction time variability. The results showed that higher genetic risk for ADHD was associated with higher ADHD traits, as well as poorer working memory performance and increased reaction time variability. Lower working memory performance, poorer response inhibition, and increased reaction time variability were associated with more pronounced ADHD traits. Working memory and reaction time variability partially mediated the relationship between genetic risk for ADHD and ADHD traits, explaining 14% and 16% of the association, respectively.
MOLECULAR PSYCHIATRY
(2022)
Article
Psychology, Developmental
Jeanette M. Johnstone, Irene Hatsu, Gabriella Tost, Priya Srikanth, Leanna P. Eiterman, Alisha M. Bruton, Hayleigh K. Ast, Lisa M. Robinette, Madeline M. Stern, Elizabeth G. Millington, Barbara L. Gracious, Andrew J. Hughes, Brenda M. Y. Leung, L. Eugene Arnold
Summary: This study evaluated whether micronutrients (vitamins/minerals) benefit ADHD and irritability in a North American pediatric sample. The results showed that micronutrients demonstrated overall benefit over placebo according to blinded clinician ratings, but did not show significant differences in parent-report composite ratings. Additionally, the micronutrient group had greater height growth.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2022)
Review
Pharmacology & Pharmacy
S. Mohammad, H. Nguyen, M. Nguyen, M. Abdel-Rasoul, V. Nguyen, C. D. Nguyen, K. T. Nguyen, L. Li, J. P. Kitzmiller
CURRENT VASCULAR PHARMACOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Chelsea R. Horwood, Daniel Mansour, Mahmoud Abdel-Rasoul, Gregory Metzger, Jing Han, Rishav Aggarwal, Mahasti Rittinger, Sheri Shimizu-Saito, Philip Diaz, Susan Moffatt-Bruce
ANNALS OF THORACIC SURGERY
(2019)
Article
Clinical Neurology
G. Sandhu, A. Gonzalez-Zacarias, J. Fiorda-Diaz, S. Soghomonyan, M. Abdel-Rasoul, L. M. Prevedello, A. A. Uribe, N. Stoicea, D. Targonski, D. M. Prevedello, S. D. Bergese
BRITISH JOURNAL OF NEUROSURGERY
(2019)
Article
Cardiac & Cardiovascular Systems
Peter J. Kneuertz, Emily Singer, Desmond M. D'Souza, Mahmoud Abdel-Rasoul, Susan D. Moffatt-Bruce, Robert E. Merritt
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2019)
Article
Immunology
Jason M. Zimmerer, Bryce A. Ringwald, Steven M. Elzein, Christina L. Avila, Robert T. Warren, Mahmoud Abdel-Rasoul, Ginny L. Bumgardner
Article
Medicine, General & Internal
Larry M. Jones, Alberto A. Uribe, Rebecca Coffey, Erika G. Puente, Mahmoud Abdel-Rasoul, Claire V. Murphy, Sergio D. Bergese
Article
Cardiac & Cardiovascular Systems
Shea Macielak, Pamela Burcham, Bryan Whitson, Mahmoud Abdel-Rasoul, Alan Rozycki
Article
Oncology
Peter J. Kneuertz, Desmond M. D'Souza, Morgan Richardson, Mahmoud Abdel-Rasoul, Susan D. Moffatt-Bruce, Robert E. Merritt
CLINICAL LUNG CANCER
(2020)
Article
Oncology
Peter J. Kneuertz, David P. Carbone, Desmond M. D'Souza, Konstantin Shilo, Mahmoud Abdel-Rasoul, Weiqiang Zhao, Terrance M. Williams, Daniel Jones, Robert E. Merritt
Article
Oncology
Robert E. Merritt, Mahmoud Abdel-Rasoul, Morgan Fitzgerald, Desmond M. D'Souza, Peter J. Kneuertz
Summary: This study aimed to create predictive nomograms for recurrence and death after lobectomy in stage I non-small-cell lung cancer patients. Nomograms can predict overall and recurrence-free survival, regardless of operative approach, providing guidance for adjuvant therapy and surveillance.
CLINICAL LUNG CANCER
(2021)
Article
Oncology
Robert E. Merritt, Mahmoud Abdel-Rasoul, Desmond M. D'Souza, Peter J. Kneuertz
Summary: Black patients with early stage NSCLC treated at academic facilities have higher rates of surgery and overall survival compared to those treated at community facilities, indicating the impact of facility type on racial disparities in NSCLC treatment outcomes.
CLINICAL LUNG CANCER
(2021)
Article
Immunology
Jason M. Zimmerer, Bryce A. Ringwald, Sachi R. Chaudhari, Jing Han, Chelsea M. Peterson, Robert T. Warren, Madison M. Hart, Mahmoud Abdel-Rasoul, Ginny L. Bumgardner
Summary: iNKT cells play a crucial role in modulating CD8-mediated immune responses in the presence or absence of CD4(+) T cells. Lack of iNKT cells decreases CD8-mediated allocytotoxicity, which can be restored by adoptive transfer of iNKT cells. including TNF-alpha and IFN-gamma.
JOURNAL OF IMMUNOLOGY
(2021)
Article
Obstetrics & Gynecology
Colleen J. Miller, Pavel Prusakov, Jacqueline Magers, Sunday Speaks, Hana Sacic, Kelsi Escobar, Mahmoud Abdel-Rasoul, Leif D. Nelin
Summary: The study found no evidence that prophylactic indomethacin (PI) administration has any benefits in preventing intraventricular hemorrhage. However, it is associated with adverse effects including acute rise in creatinine.
JOURNAL OF PERINATOLOGY
(2022)
Article
Surgery
Dahlia M. Kenawy, Ruth L. Ackah, Mahmoud Abdel-Rasoul, Muna M. Tamimi, Gwendolyn M. Thomas, Tyler A. Roach, Desmond M. D'Souza, Robert E. Merritt, Peter J. Kneuertz
Summary: This study aimed to characterize intraoperative delays during robotic-assisted thoracic surgery, investigate the awareness of delays among operating room staff, and assess the cost impact of delays. A total of 44 cases were observed, with 71 delays recorded. The study found that the operating room team had lower detection rates for delays compared to observers, and delays contributed to increased operative costs.
Article
Public, Environmental & Occupational Health
Kristin J. Roberts, Erica Fowler, R. Dawn Comstock, Soledad Fernandez, Mahmoud Abdel-Rasoul, Leslie Mihalov, Marcel J. Casavant, Lara B. McKenzie
JOURNAL OF PRIMARY PREVENTION
(2018)