期刊
JOURNAL OF CHEMICAL PHYSICS
卷 129, 期 9, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.2972981
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资金
- NIH, Center for Information Technology
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Russian Foundation [08-02-00314a]
We analyze the relaxation of the particle number fluctuations in a membrane channel at arbitrary particle-channel interaction and derive general expressions for the relaxation time and low-frequency limit of the power spectral density. These expressions simplify significantly when the channel is symmetric. For a square-well potential of mean force that occupies the entire channel, we verify the accuracy of the analytical predictions by Brownian dynamics simulations. For such a channel we show that as the depth of the well increases, the familiar scaling of the relaxation time with the channel length squared is transformed into a linear dependence on the length. (C) 2008 American Institute of Physics.
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