Brain Alanine Formation as an Ammonia-Scavenging Pathway during Hyperammonemia: Effects of Glutamine Synthetase Inhibition in Rats and Astrocyte—Neuron Co-Cultures

siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate

(2012) Dorte M. Skytt et al.   NEUROCHEMISTRY INTERNATIONAL

A glutamine synthetase inhibitor increases survival and decreases cytokine response in a mouse model of acute liver failure

(2011) Amruta A. Jambekar et al.   LIVER INTERNATIONAL

Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

(2011) Sherry Dadsetan et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroimaging in acute liver failure

(2011) Laia Chavarria et al.   NEUROCHEMISTRY INTERNATIONAL

Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal

(2010) Jan Albrecht et al.   BIOCHEMICAL PHARMACOLOGY

Detoxification of Ammonia in Mouse Cortical GABAergic Cell Cultures Increases Neuronal Oxidative Metabolism and Reveals an Emerging Role for Release of Glucose-Derived Alanine

(2010) Renata Leke et al.   NEUROTOXICITY RESEARCH

Pathogenetic mechanisms of hepatic encephalopathy

(2008) D Haussinger et al.   GUT

Demonstration of Neuron-Glia Transfer of Precursors for Gaba Biosynthesis in a Co-Culture System of Dissociated Mouse Cerebral Cortex

(2008) Renata Leke et al.   NEUROCHEMICAL RESEARCH