In silico evidence of direct interaction between statins and β-amyloid

Protection against the Neurotoxic Effects of β-Amyloid Peptide on Cultured Neuronal Cells by Lovastatin Involves Elevated Expression of α7 Nicotinic Acetylcholine Receptors and Activating Phosphorylation of Protein Kinases

(2018) Liang Zhao et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuroprotective effects of statins against amyloid β-induced neurotoxicity

(2018) Chien-Ning Huang et al.   Neural Regeneration Research

Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis

(2018) Che-Sheng Chu et al.   Scientific Reports

The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms

(2018) Bob G. Schultz et al.   Translational Neurodegeneration

NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer’s disease: an investigation by docking, molecular dynamics, and DFT studies

(2017) Faizul Azam et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Effect of simvastatin on CSF Alzheimer disease biomarkers in cognitively normal adults

(2017) Ge Li et al.   NEUROLOGY

Impact of statin therapy on plasma adiponectin concentrations: A systematic review and meta-analysis of 43 randomized controlled trial arms

(2016) Piotr Chruściel et al.   ATHEROSCLEROSIS

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults

(2016) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβby Using Several Synthetic and Herbal Compounds

(2016) Sandeep Kumar Singh et al.   Oxidative Medicine and Cellular Longevity

The impact of statin therapy on plasma levels of von Willebrand factor antigen

(2016) Amirhossein Sahebkar et al.   THROMBOSIS AND HAEMOSTASIS

Current Research Therapeutic Strategies for Alzheimer’s Disease Treatment

(2016) Jaume Folch et al.   NEURAL PLASTICITY

Statin therapy reduces plasma endothelin-1 concentrations: A meta-analysis of 15 randomized controlled trials

(2015) Amirhossein Sahebkar et al.   ATHEROSCLEROSIS

Do statins prevent Alzheimer's disease? A narrative review

(2015) Homayoun L. Daneschvar et al.   European Journal of Internal Medicine

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Statin therapy and plasma coenzyme Q10 concentrations—A systematic review and meta-analysis of placebo-controlled trials

(2015) Maciej Banach et al.   PHARMACOLOGICAL RESEARCH

Association between statin use and plasma D-dimer levels

(2015) Dimitri Mikhailidis et al.   THROMBOSIS AND HAEMOSTASIS

A systematic review and meta-analysis of the effect of statins on plasma asymmetric dimethylarginine concentrations

(2015) Corina Serban et al.   Scientific Reports

Statin use and incident dementia: A nationwide cohort study of Taiwan

(2014) Chian-Ying Chou et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Molecular Mechanisms Underlying the Effects of Statins in the Central Nervous System

(2014) Amelia McFarland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Statin use reduces the risk of dementia in elderly patients: a nationwide data survey and propensity analysis

(2014) C.-K. Wu et al.   JOURNAL OF INTERNAL MEDICINE

MiR128 up-regulation correlates with impaired beta-amyloid 42 degradation in monocytes of patients with sporadic Alzheimer's disease

(2013) Roberto Tiribuzi et al.   Alzheimers & Dementia

Dual Effects of Statins on Aß Metabolism: Upregulation of the Degradation of APP-CTF and Aß Clearance

(2012) Naoyuki Sato et al.   Neurodegenerative Diseases

Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer’s disease

(2012) Tomoko Kurata et al.   NEUROLOGICAL RESEARCH

Cholesterol Level and Statin Use in Alzheimer Disease

(2011) Nina E. Shepardson   ARCHIVES OF NEUROLOGY

Simvastatin Therapy Reduces Prooxidant-Antioxidant Balance: Results of a Placebo-Controlled Cross-Over Trial

(2011) Seyyed M. R. Parizadeh et al.   LIPIDS

A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

(2011) M. Sano et al.   NEUROLOGY

Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion

(2010) Irfan Y. Tamboli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY