mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring anEGFRactivating mutation by inducing autophagy

PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy

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Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death

(2011) W Gao et al.   CELL DEATH AND DIFFERENTIATION

Mechanisms of mTOR inhibitor resistance in cancer therapy

(2011) Jennifer S. Carew et al.   Targeted Oncology

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Cytoprotective roles for autophagy

(2010) Kevin Moreau et al.   CURRENT OPINION IN CELL BIOLOGY

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

The Beclin 1 interactome

(2010) Congcong He et al.   CURRENT OPINION IN CELL BIOLOGY

Inducible EGFR T790M-Mediated Gefitinib Resistance in Non-small Cell Lung Cancer Cells Does Not Modulate Sensitivity to PI103 Provoked Autophagy

(2010) Flavia F. Moreira-Leite et al.   Journal of Thoracic Oncology

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Understanding resistance to EGFR inhibitors—impact on future treatment strategies

(2010) Deric L. Wheeler et al.   Nature Reviews Clinical Oncology

The mTOR Inhibitor Rapamycin Suppresses DNA Double-Strand Break Repair

(2010) Honghong Chen et al.   RADIATION RESEARCH

The role of autophagy in sensitizing malignant glioma cells to radiation therapy

(2009) W. Zhuang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Radiation-induced autophagy in normal and cancer cells: Towards novel cytoprotection and radio-sensitization policies?

(2009) Christos E. Zois et al.   Autophagy

PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

(2009) M. L. Sos et al.   CANCER RESEARCH

Enhancing mTOR-targeted cancer therapy

(2009) Xuerong Wang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions

(2009) Martin L. Sos et al.   JOURNAL OF CLINICAL INVESTIGATION

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC

(2009) Helena Linardou et al.   Nature Reviews Clinical Oncology

Promotion of autophagy as a mechanism for radiation sensitization of breast tumor cells

(2009) David A. Gewirtz et al.   RADIOTHERAPY AND ONCOLOGY

Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs

(2008) R Bianco et al.   BRITISH JOURNAL OF CANCER

Antiangiogenic Therapy with Mammalian Target of Rapamycin Inhibitor RAD001 (Everolimus) Increases Radiosensitivity in Solid Cancer

(2008) P. C. Manegold et al.   CLINICAL CANCER RESEARCH

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

The Potential Role of mTOR Inhibitors in Non-Small Cell Lung Cancer

(2008) C. Gridelli et al.   ONCOLOGIST