LTBPs, more than just an escort service

Latent Transforming Growth Factor β-Binding Proteins-2 and -3 Inhibit the Proprotein Convertase 5/6A

(2011) Xiaowei Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Choreographing Metastasis to the Tune of LTBP

(2011) Anupama Chandramouli et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Noncanonical TGF  Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

(2011) T. M. Holm et al.   SCIENCE

TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs

(2010) Ian Robertson et al.   BIOCHEMICAL JOURNAL

Long form of latent TGF-β binding protein 1 (Ltbp1L) regulates cardiac valve development

(2010) Vesna Todorovic et al.   DEVELOPMENTAL DYNAMICS

Two Distinct Regions of Latency-associated Peptide Coordinate Stability of the Latent Transforming Growth Factor-β1 Complex

(2010) Kelly L. Walton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF 

(2010) T. Massam-Wu et al.   JOURNAL OF CELL SCIENCE

LTBP-2 has multiple heparin/heparan sulfate binding sites

(2010) Mahroo K. Parsi et al.   MATRIX BIOLOGY

Oligodontia Is Caused by Mutation in LTBP3, the Gene Encoding Latent TGF-β Binding Protein 3

(2009) Abdul Noor et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in LTBP4 Cause a Syndrome of Impaired Pulmonary, Gastrointestinal, Genitourinary, Musculoskeletal, and Dermal Development

(2009) Zsolt Urban et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Latent Transforming Growth Factor β-binding Proteins and Fibulins Compete for Fibrillin-1 and Exhibit Exquisite Specificities in Binding Sites

(2009) Robert N. Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1

(2009) Piia Vehviläinen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase

(2009) Masahito Horiguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibronectin and heparin binding domains of latent TGF-β binding protein (LTBP)-4 mediate matrix targeting and cell adhesion

(2008) A KANTOLA et al.   EXPERIMENTAL CELL RESEARCH

p38 MAPK Is an Early Determinant of Promiscuous Smad2/3 Signaling in the Aortas of Fibrillin-1 (Fbn1)-null Mice

(2008) Luca Carta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Pool of Extracellular Pro-myostatin in Skeletal Muscle

(2008) Sarah B. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-β activity

(2008) Branka Dabovic et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-β bioavailability regulation

(2008) Carine Le Goff et al.   NATURE GENETICS

Perturbation of transforming growth factor (TGF)-ss1 association with latent TGF-  binding protein yields inflammation and tumors

(2008) K. Yoshinaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of the latent transforming growth factor-β binding protein-1 gene causes alteration in facial structure and influences TGF-β bioavailability

(2007) Falko Drews et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH