Aptamers: A promising tool for cancer imaging, diagnosis, and therapy

Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro

(2012) Yan Hu et al.   PLoS One

Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy

(2011) Microsugar Chang et al.   ACS Nano

Aptamer-Conjugated Nanoparticles for Cancer Cell Detection

(2011) Colin D. Medley et al.   ANALYTICAL CHEMISTRY

Characterization of Peptide Aptamers Targeting Bfl-1 Anti-Apoptotic Protein

(2011) G. Brien et al.   BIOCHEMISTRY

Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle

(2011) Jin Kyeoung Kim et al.   BIOMATERIALS

An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells

(2011) Yun-Hee Kim et al.   CANCER LETTERS

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

(2011) Sarah Shigdar et al.   CANCER SCIENCE

Chimeric aptamers in cancer cell-targeted drug delivery

(2011) Jagat R. Kanwar et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Designed Cell-Permeable Aptamer-Based Corepressor Peptide Is Highly Specific for the Androgen Receptor and Inhibits Prostate Cancer Cell Growth in a Vector-Free Mode

(2011) Christina A. Reeb et al.   ENDOCRINOLOGY

Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts

(2011) Xiaohua Ni et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer

(2011) Ronak Savla et al.   JOURNAL OF CONTROLLED RELEASE

PEGylated Anti-MUC1 Aptamer-Doxorubicin Complex for Targeted Drug Delivery to MCF7 Breast Cancer Cells

(2011) Lihan Tan et al.   MACROMOLECULAR BIOSCIENCE

Capturing cancer cells using aptamer-immobilized square capillary channels

(2011) Jennifer A. Martin et al.   Molecular BioSystems

Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer

(2011) Rachel M. Ostroff et al.   PLoS One

Novel Aptamer-Nanoparticle Bioconjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro

(2011) Chenchen Yu et al.   PLoS One

Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

(2011) H. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7

(2011) Jyoti Bala et al.   RNA Biology

Pharmacokinetic characterization of an RNA aptamer against osteopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells

(2011) Lindsay Jones Talbot et al.   SURGERY

In Vitro Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells

(2011) Mee Young Kim et al.   Nucleic Acid Therapeutics

A Drug-Loaded Aptamer−Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer

(2010) Dongkyu Kim et al.   ACS Nano

Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex

(2010) Eunjung Kim et al.   BIOMATERIALS

The formulation of aptamer-coated paclitaxel–polylactide nanoconjugates and their targeting to cancer cells

(2010) Rong Tong et al.   BIOMATERIALS

Targeting Id1 and Id3 by a specific peptide aptamer induces E-box promoter activity, cell cycle arrest, and apoptosis in breast cancer cells

(2010) Demissew S. Mern et al.   BREAST CANCER RESEARCH AND TREATMENT

Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells

(2010) D S Mern et al.   BRITISH JOURNAL OF CANCER

Simultaneous electrochemical detection of both PSMA (+) and PSMA (−) prostate cancer cells using an RNA/peptide dual-aptamer probe

(2010) Kyoungin Min et al.   CHEMICAL COMMUNICATIONS

In vivo Fluorescence Imaging of Tumors using Molecular Aptamers Generated by Cell-SELEX

(2010) Hui Shi et al.   Chemistry-An Asian Journal

Utility of aptamer-fluorescence in situ hybridization for rapid detection of Pseudomonas aeruginosa

(2010) K.-Y. Wang et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Reversible Targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes

(2010) Seyed Mohammad Taghdisi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Bioimaging of Nucleolin Aptamer-Containing 5-(N-benzylcarboxyamide)-2′-deoxyuridine More Capable of Specific Binding to Targets in Cancer Cells

(2010) Kyue Yim Lee et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Using Aptamer-Conjugated Fluorescence Resonance Energy Transfer Nanoparticles for Multiplexed Cancer Cell Monitoring

(2009) Xiaolan Chen et al.   ANALYTICAL CHEMISTRY

Aptamer−Nanoparticle Strip Biosensor for Sensitive Detection of Cancer Cells

(2009) Guodong Liu et al.   ANALYTICAL CHEMISTRY

Aptamer–biotin–streptavidin–C1q complexes can trigger the classical complement pathway to kill cancer cells

(2009) John Gordon Bruno   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

A Nucleolin-Targeted Multimodal Nanoparticle Imaging Probe for Tracking Cancer Cells Using an Aptamer

(2009) D. W. Hwang et al.   JOURNAL OF NUCLEAR MEDICINE

Modulation of transcription by the peroxisome proliferator-activated receptor  -binding RNA aptamer in colon cancer cells

(2009) H. Kwak et al.   MOLECULAR CANCER THERAPEUTICS

Electrical detection of VEGFs for cancer diagnoses using anti-vascular endotherial growth factor aptamer-modified Si nanowire FETs

(2008) Hyun-Seung Lee et al.   BIOSENSORS & BIOELECTRONICS

The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells

(2008) S. Soundararajan et al.   CANCER RESEARCH

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

(2008) Dihua Shangguan et al.   JOURNAL OF PROTEOME RESEARCH

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Aptamer-targeted Inhibition of NF-κB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin

(2007) Jing Mi et al.   MOLECULAR THERAPY