Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells

Protein kinase C: poised to signal

(2009) Alexandra C. Newton   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phase Ib safety and pharmacokinetic evaluation of daily and twice daily oral enzastaurin in combination with pemetrexed in advanced/metastatic cancer

(2009) A.-R. Hanauske et al.   ANNALS OF ONCOLOGY

A Phase I Trial of Enzastaurin in Patients with Recurrent Gliomas

(2009) T. N. Kreisl et al.   CLINICAL CANCER RESEARCH

Protein Kinase Cβ Modulates Ligand-induced Cell Surface Death Receptor Accumulation

(2009) Xue Wei Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatiotemporal dynamics of lipid signaling: Protein kinase C as a paradigm

(2008) Lisa L. Gallegos et al.   IUBMB LIFE

PKR Regulates B56α-mediated BCL2 Phosphatase Activity in Acute Lymphoblastic Leukemia-derived REH Cells

(2008) Vivian R. Ruvolo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzastaurin, an Oral Serine/Threonine Kinase Inhibitor, As Second- or Third-Line Therapy of Non–Small-Cell Lung Cancer

(2008) Yun Oh et al.   JOURNAL OF CLINICAL ONCOLOGY

Protein kinase C signalling in leukemia

(2008) Amanda J. Redig et al.   LEUKEMIA & LYMPHOMA

A phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory mantle cell lymphoma

(2007) F. Morschhauser et al.   ANNALS OF ONCOLOGY