Article
Neurosciences
Viljami Sairanen, Mario Ocampo-Pineda, Cristina Granziera, Simona Schiavi, Alessandro Daducci
Summary: This study introduces an enhanced filtering algorithm to address motion artefacts in human brain structural connectivity analysis, demonstrating its effectiveness through comprehensive Monte-Carlo simulations and infant data. This robust filtering method proves to be beneficial in clinical studies with uncooperative patient groups.
Article
Neurosciences
Syed M. Adil, Evan Calabrese, Lefko T. Charalambous, James J. Cook, Shervin Rahimpour, Ahmet F. Atik, Gary P. Cofer, Beth A. Parente, G. Allan Johnson, Shivanand P. Lad, Leonard E. White
Summary: This study successfully constructed an atlas of the human brainstem using high-resolution MRI technology, which is available online for interactive use, providing a new tool for neuroanatomical education and research.
Article
Neurosciences
Chengyuan Wu, Francisca Ferreira, Michael Fox, Noam Harel, Jona Hattangadi-Gluth, Andreas Horn, Saad Jbabdi, Joshua Kahan, Ashwini Oswal, Sameer A. Sheth, Yanmei Tie, Vejay Vakharia, Ludvic Zrinzo, Harith Akram
Summary: Advances in computational neuroimaging techniques have expanded the arsenal of imaging tools available for clinical neuroscience, allowing for identification of therapeutic targets, preservation of eloquent brain regions, and insight into pathological processes and treatments. However, factors such as data quality, processing methodology, and statistical models can impact results. Lack of standardization in data acquisition and processing has led to issues with reproducibility.
Review
Medicine, General & Internal
Tzu-Hsin Huang, Ming-Chi Lai, Yu-Shiue Chen, Chin-Wei Huang
Summary: This review focuses on the fundamentals of DWI and its associated techniques, such as apparent diffusion coefficient, diffusion tensor imaging, and tractography, as well as their impact on epilepsy in terms of differential diagnosis, epileptic foci determination, and prognosis prediction.
Article
Neurosciences
Sami Obaid, Francois Rheault, Manon Edde, Guido Guberman, Etienne St-Onge, Jasmeen Sidhu, Alain Bouthillier, Alessandro Daducci, Jimmy Ghaziri, Michel W. Bojanowski, Dang K. Nguyen, Maxime Descoteaux
Summary: Operculo-insular epilepsy (OIE) is a condition that can mimic temporal and extratemporal epilepsies and often involves increased connectivity strength between certain brain regions. The study proposed a cutting-edge method that revealed widespread connectivity alterations in the OIE group, indicating a diffuse epileptic network within the brain. Graph theoretic analyses showed higher connectivity within insular subregions of OIE patients compared to those with temporal lobe epilepsy.
Article
Neurosciences
Kevin T. Jones, Elizabeth L. Johnson, Adam Gazzaley, Theodore P. Zanto
Summary: Age-related declines in cognitive control can threaten individual independence. This study demonstrates that transcranial alternating current stimulation (tACS) can improve cognitive control in older adults by strengthening functional connectivity, particularly in higher frequency bands.
Article
Clinical Neurology
Joshua A. Adkinson, Evangelia Tsolaki, Sameer A. Sheth, Brian A. Metzger, Meghan E. Robinson, Denise Oswalt, Cameron C. McIntyre, Raissa K. Mathura, Allison C. Waters, Anusha B. Allawala, Angela M. Noecker, Mahsa Malekmohammadi, Kevin Chiu, Richard Mustakos, Wayne Goodman, David Borton, Nader Pouratian, Kelly R. Bijanki
Summary: This study investigates the connectivity between stimulation targets and mood-related networks in psychiatric DBS patients using a multimodal approach. The results demonstrate both similarities and differences between tractography-predicted structural connectivity and stimulation-induced electrophysiological responses, providing new insights for surgical targeting and network-wide effects of neuromodulation.
Article
Neurosciences
J. J. Levitt, F. Zhang, M. Vangel, P. G. Nestor, Y. Rathi, M. Kubicki, M. E. Shenton, L. J. O'Donnell
Summary: The study analyzed the brain wiring between the frontal cortex and caudate in 100 young adult healthy subjects using dMRI scans. It found that the wiring pattern deviates from a strictly topographic organization due to significant convergence in regionally specific fiber clusters, originating from subregions of ventrolateral, dorsolateral, and orbitofrontal prefrontal cortex. This deviation suggests a regionally specific pattern of cluster convergence in the brain wiring.
Article
Neurosciences
Ryo Kurokawa, Kouhei Kamiya, Shinsuke Koike, Moto Nakaya, Akiko Uematsu, Saori C. Tanaka, Koji Kamagata, Naohiro Okada, Kentaro Morita, Kiyoto Kasai, Osamu Abe
Summary: Characterization of brain networks using diffusion MRI has seen rapid advancements, especially in the context of data sharing and multi-center studies. This study highlights the need for harmonization methods to correct bias caused by scanner differences in structural network analyses. The study demonstrates lower reliability of edge weights and graph theory metrics in data from different scanners compared to scan-rescan data from the same scanner, indicating potential systematic differences between scanners and the risk of bias in direct comparison of networks from different scanners. By modeling scanner effects at the level of network matrices using traveling-subject data, it is possible to reduce inter-scanner variabilities while preserving inter-subject differences among healthy individuals.
Article
Clinical Neurology
Si-ping Luo, Fan-fan Chen, Han-wen Zhang, Fan Lin, Guo-dong Huang, Yi Lei
Summary: This study used DSI to quantitatively study the changes in the trigeminal cistern segment in patients with TN and found significant reductions in quantitative parameters on the affected side compared to the unaffected side. DSI, with its high-resolution fiber tracking technology, can provide valuable information about the integrity of trigeminal white matter in TN patients.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Fengzhao Zhu, Yulong Wang, Xiangchuang Kong, Yuan Liu, Lian Zeng, Xirui Jing, Sheng Yao, Kaifang Chen, Lian Yang, Xiaodong Guo
Summary: The combination of conventional MRI with DTI-DTT is a valid diagnostic approach for acute traumatic cervical SCI. Lower intramedullary lesion length and intramedullary hemorrhage length, and higher fractional anisotropy value and connection rates of fiber tractography are linked to better neurological outcomes.
EUROPEAN SPINE JOURNAL
(2022)
Article
Pediatrics
Maria E. Barnes-Davis, Brady J. Williamson, Stephanie L. Merhar, Usha D. Nagaraj, Nehal A. Parikh, Darren S. Kadis
Summary: Children born extremely preterm are at risk for language delay or disorders. Previous research found that increased functional connectivity is associated with better language outcome in preterm children. This study aimed to validate this finding and compare structural connectivity in preterm children with and without language delay or disorder. The results identified specific brain pathways positively associated with language scores and showed that increased functional connectivity explains a significant portion of the variance in language scores.
FRONTIERS IN PEDIATRICS
(2022)
Article
Clinical Neurology
Yeji Moon, Jin-Ju Yang, Won June Lee, Ji Young Lee, Yu Jeong Kim, Han Woong Lim
Summary: This study quantitatively investigated the microstructural properties of the optic nerve in an elderly population using dMRI tractography, revealing a negative correlation between FA and age. Females exhibited significantly higher FA than males.
FRONTIERS IN NEUROLOGY
(2021)
Article
Multidisciplinary Sciences
Hu Cheng, Sophia Vinci-Booher, Jian Wang, Bradley Caron, Qiuting Wen, Sharlene Newman, Franco Pestilli
Summary: This study proposes a simple denoising method using a one-dimensional convolutional neural network (1D-CNN) and deep learning to learn from a low-noise dataset, and applies it to high-noise datasets. The results show that this method produces DWI images that are more similar to noise-free ground truth compared to other methods, and also shows promising results in diffusion metrics and tractography.
Article
Neuroimaging
Tobias Mantel, Angela Jochim, Tobias Meindl, Jonas Deppe, Claus Zimmer, Yong Li, Bernhard Haslinger
Summary: Through diffusion imaging study of patients with blepharospasm and healthy controls, we found abnormal brain connectivity in patients, especially in connections related to vision and movement. The cerebellum may also contribute to the occurrence of this disease.
NEUROIMAGE-CLINICAL
(2022)
Review
Biophysics
Flavio Dell'Acqua, J. -Donald Tournier
NMR IN BIOMEDICINE
(2019)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Robert E. Smith, Fernando Calamante, Alan Connelly
MAGNETIC RESONANCE IN MEDICINE
(2020)
Review
Medicine, General & Internal
Fernando Calamante
Article
Computer Science, Interdisciplinary Applications
Maria Deprez, Anthony Price, Daan Christiaens, Georgia Lockwood Estrin, Lucilio Cordero-Grande, Jana Hutter, Alessandro Daducci, Jacques-Donald Tournier, Mary Rutherford, Serena J. Counsell, Merixtell Bach Cuadra, Joseph Hajnal
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2020)
Letter
Radiology, Nuclear Medicine & Medical Imaging
Robert E. Smith, Fernando Calamante, Alan Connelly
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Neurosciences
Stuart Oldham, Aurina Arnatkeviciute, Robert E. Smith, Jeggan Tiego, Mark A. Bellgrove, Alex Fornito
Article
Biophysics
Jacques-Donald Tournier, Daan Christiaens, Jana Hutter, Anthony N. Price, Lucilio Cordero-Grande, Emer Hughes, Matteo Bastiani, Stamatios N. Sotiropoulos, Stephen M. Smith, Daniel Rueckert, Serena J. Counsell, A. David Edwards, Joseph V. Hajnal
NMR IN BIOMEDICINE
(2020)
Article
Neurosciences
Ana A. Baburamani, Regina T. Vontell, Alena Uus, Maximilian Pietsch, Prachi A. Patkee, Jo Wyatt-Ashmead, Evonne C. Chin-Smith, Veena G. Supramaniam, J. Donald Tournier, Maria Deprez, Mary A. Rutherford
ACTA NEUROPATHOLOGICA COMMUNICATIONS
(2020)
Article
Oncology
Charlotte Sleurs, Sandra Jacobs, Serena J. Counsell, Daan Christiaens, J. -Donald Tournier, Stefan Sunaert, Karen Van Beek, Anne Uyttebroeck, Sabine Deprez, Dafnis Batalle, Jurgen Lemiere
Summary: The study revealed significant changes in the brain network structure of childhood infratentorial tumor survivors, especially in the network hubs. These hubs were not only most affected, but also most strongly correlated with intellectual outcomes.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Psychiatry
Alexandra Lautarescu, Alexandra F. Bonthrone, Maximilian Pietsch, Dafnis Batalle, Lucilio Cordero-Grande, J-Donald Tournier, Daan Christiaens, Joseph Hajnal, Andrew Chew, Shona Falconer, Chiara Nosarti, Suresh Victor, Michael C. Craig, A. David Edwards, Serena J. Counsell
Summary: Maternal prenatal depression is associated with neurodevelopmental and behavioral outcomes in offspring. This study found a positive association between maternal depressive symptoms and infant white matter density in the uncinate fasciculus, as well as a positive association between left uncinate fasciculus density and toddler social-emotional abilities.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Michaela Bartonova, Jacques-Donald Tournier, Marek Barton, Pavel Riha, Lubomir Vojtisek, Radek Marecek, Irena Dolezalova, Ivan Rektor
Summary: This study investigates white matter alterations in pharmacoresistant epilepsy patients who don't have visible lesions on clinical MRI. The study used fixel-based analysis to compare fixel parameters between healthy controls and frontal lobe epilepsy (FLE) patients and temporal lobe epilepsy (TLE) patients. The results showed specific alterations in different brain regions for both FLE and TLE patients.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jonathan Shapey, Sjoerd B. Vos, Laura Mancini, Brett Sanders, John S. Thornton, Jacques-Donald Tournier, Shakeel R. Saeed, Neil Kitchen, Sherif Khalil, Patrick Grover, Robert Bradford, Reuben Dorent, Rachel Sparks, Tom Vercauteren, Tarek Yousry, Sotirios Bisdas, Sebastien Ourselin
Summary: This study aimed to optimize a multi-shell rs-DWI protocol and develop a novel post-processing pipeline to accurately delineate the facial-vestibulocochlear complex within the skull base region, and evaluate its intraoperative accuracy using neuronavigation and tracked electrophysiological recordings.
EUROPEAN RADIOLOGY
(2023)
Article
Neurosciences
L. Sina Mansour, Maria A. Di Biase, Robert E. Smith, Andrew Zalesky, Caio Seguin
Summary: This study maps functional and structural brain networks for over 40,000 UK Biobank participants, providing high-quality connectomes and various options for researchers. The connectomes can be used for studies in health, disease, and aging at an unprecedented scale.
Article
Clinical Neurology
J. A. Kimpton, D. Batalle, M. L. Barnett, E. J. Hughes, A. T. M. Chew, S. Falconer, J. D. Tournier, D. Alexander, H. Zhang, A. D. Edwards, S. J. Counsell
Summary: The study explored the microstructural maturation of white matter in preterm neonates using diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI) metrics, finding that NODDI provides more accurate estimations of neurite architecture compared to DTI. Through analyzing DTI and NODDI metrics, the researchers discovered asynchronous white matter maturation within and between tracts in preterm neonates with normal neurodevelopmental outcomes.
Article
Neuroimaging
Yi-Ai Rau, Shi-Ming Wang, Jacques-Donald Tournier, Sung-Han Lin, Chin-Song Lu, Yi-Hsin Weng, Yao-Liang Chen, Shu-Hang Ng, Shao-Wen Yu, Yi-Ming Wu, Chih-Chien Tsai, Jiun-Jie Wang
NEUROIMAGE-CLINICAL
(2019)
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.