期刊
NEUROIMAGE
卷 119, 期 -, 页码 119-128出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2015.06.014
关键词
Diffusion tensor imaging; Neuropsychological performance; Brain development; Population-based imaging; MRI
资金
- Sophia Children's Hospital Research Foundation (SSWO)
- Netherlands Organization for Health Research and Development (ZonMw) [91211021]
- European Community's 7th Framework Programme [212652]
- NWO Physical Sciences Division (Exacte Wetenschappen)
- SURFsara
Child and adolescent brain development are typically accompanied by marked improvements in a wide range of cognitive abilities. However, limited information is available surrounding the role of white matter in shaping cognitive abilities in children. The current study examined associations between white matter microstructure and cognitive performance in a large sample (n = 778) of 6- to 10-year-old children. Results show white matter microstructure is related to non-verbal intelligence and to visuospatial ability, independent of age. Specificity was demonstrated, as white matter associations with visuospatial ability were independent of general intellectual ability. Associations between white matter integrity and cognition were similar in boys and girls. In summary, results demonstrate white matter structure-function associations are present in children, independent of age and broader cognitive abilities. The presence of such associations in the general population is informative for studies examining child psychopathology (C) 2015 Elsevier Inc. All rights reserved.
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