Two sides to every story: the HIF-dependent and HIF-independent functions of pVHL

NF- B-Dependent Plasticity of the Epithelial to Mesenchymal Transition Induced by Von Hippel-Lindau Inactivation in Renal Cell Carcinomas

(2010) A. J. Pantuck et al.   CANCER RESEARCH

Renal Oxygenation Suppresses VHL Loss-Induced Senescence That Is Caused by Increased Sensitivity to Oxidative Stress

(2010) S. M. Welford et al.   MOLECULAR AND CELLULAR BIOLOGY

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

(2010) Ataman Sendoel et al.   NATURE

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney

(2009) R. Beroukhim et al.   CANCER RESEARCH

Renal Cystic Diseases and Renal Neoplasms: A Mini-Review

(2009) S. M. Bonsib   Clinical Journal of the American Society of Nephrology

VHL Inactivation: A New Road to Senescence

(2008) William Y. Kim et al.   CANCER CELL

HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

(2008) John D. Gordan et al.   CANCER CELL

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

(2008) Sandra Turcotte et al.   CANCER CELL

pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation

(2008) Ian J Frew et al.   EMBO JOURNAL

NEDD8 acts as a ‘molecular switch’ defining the functional selectivity of VHL

(2008) Ryan C Russell et al.   EMBO REPORTS

Abnormal Sympathoadrenal Development and Systemic Hypotension in PHD3-/- Mice

(2008) T. Bishop et al.   MOLECULAR AND CELLULAR BIOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400

(2008) Arthur P. Young et al.   NATURE CELL BIOLOGY

Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screen

(2008) A. Bommi-Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA