BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis

ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing

(2013) H. Royo et al.   GENES & DEVELOPMENT

Regulation of the DNA damage response on male meiotic sex chromosomes

(2013) Lin-Yu Lu et al.   Nature Communications

SPO11-Independent DNA Repair Foci and Their Role in Meiotic Silencing

(2013) Fabrizia Carofiglio et al.   PLoS Genetics

Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways

(2012) Yosuke Ichijima et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

(2012) Martijn S Luijsterburg et al.   EMBO JOURNAL

RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids

(2012) H.-S. Sin et al.   GENES & DEVELOPMENT

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms

(2012) L. Wojtasz et al.   GENES & DEVELOPMENT

HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity

(2012) Hiroshi Kogo et al.   GENES TO CELLS

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes

(2012) Hiroshi Kogo et al.   GENES TO CELLS

MDC1 and RNF8 function in a pathway that directs BRCA1-dependent localization of PALB2 required for homologous recombination

(2012) F. Zhang et al.   JOURNAL OF CELL SCIENCE

BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair

(2012) Samuel F. Bunting et al.   MOLECULAR CELL

Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis

(2012) Tomoyuki Fukuda et al.   PLoS Genetics

MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells

(2011) Y. Ichijima et al.   GENES & DEVELOPMENT

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

ATM controls meiotic double-strand-break formation

(2011) Julian Lange et al.   NATURE

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1

(2011) Katrin Daniel et al.   NATURE CELL BIOLOGY

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

Detection of nascent RNA, single-copy DNA and protein localization by immunoFISH in mouse germ cells and preimplantation embryos

(2011) Satoshi H Namekawa et al.   Nature Protocols

Small Noncoding RNAs in the Germline

(2011) J. P. Saxe et al.   Cold Spring Harbor Perspectives in Biology

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Evidence that Meiotic Sex Chromosome Inactivation Is Essential for Male Fertility

(2010) Hélène Royo et al.   CURRENT BIOLOGY

RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis

(2010) Lin-Yu Lu et al.   DEVELOPMENTAL CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

(2010) Peter Bouwman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Meiotic Recombination Provokes Functional Activation of the p53 Regulatory Network

(2010) W.-J. Lu et al.   SCIENCE

Hormad1 Mutation Disrupts Synaptonemal Complex Formation, Recombination, and Chromosome Segregation in Mammalian Meiosis

(2010) Yong-Hyun Shin et al.   PLoS Genetics

miRExpress: Analyzing high-throughput sequencing data for profiling microRNA expression

(2009) Wei-Chi Wang et al.   BMC BIOINFORMATICS

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2

(2009) F. Zhang et al.   MOLECULAR CANCER RESEARCH

Chromosome-wide Rad51 Spreading and SUMO-H2A.Z-Dependent Chromosome Fixation in Response to a Persistent DNA Double-Strand Break

(2009) Marian Kalocsay et al.   MOLECULAR CELL

BRCA1 and its toolbox for the maintenance of genome integrity

(2009) Michael S.Y. Huen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase

(2009) Lukasz Wojtasz et al.   PLoS Genetics

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Epigenetic regulation of heterochromatic DNA stability

(2008) Jamy C Peng et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY