Cellular and molecular mechanisms underlying axon formation, growth, and branching

Terminal Axon Branching Is Regulated by the LKB1-NUAK1 Kinase Pathway via Presynaptic Mitochondrial Capture

(2013) Julien Courchet et al.   CELL

MAP1B regulates microtubule dynamics by sequestering EB1/3 in the cytosol of developing neuronal cells

(2013) Elena Tortosa et al.   EMBO JOURNAL

Axonal Translation of  -Catenin Regulates Synaptic Vesicle Dynamics

(2013) A. M. Taylor et al.   JOURNAL OF NEUROSCIENCE

Axonally Synthesized  -Actin and GAP-43 Proteins Support Distinct Modes of Axonal Growth

(2013) C. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

Long-distance retrograde neurotrophic factor signalling in neurons

(2013) Anthony W. Harrington et al.   NATURE REVIEWS NEUROSCIENCE

SAD Kinases Sculpt Axonal Arbors of Sensory Neurons through Long- and Short-Term Responses to Neurotrophin Signals

(2013) Brendan N. Lilley et al.   NEURON

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

(2013) Myrrhe van Spronsen et al.   NEURON

Kinesin-1 regulates dendrite microtubule polarity in Caenorhabditis elegans

(2013) Jing Yan et al.   eLife

Early Events in Axon/Dendrite Polarization

(2012) Pei-lin Cheng et al.   Annual Review of Neuroscience

The RacGAP β2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus

(2012) Martin M. Riccomagno et al.   CELL

A Distal Axonal Cytoskeleton Forms an Intra-Axonal Boundary that Controls Axon Initial Segment Assembly

(2012) Mauricio R. Galiano et al.   CELL

Septin-Driven Coordination of Actin and Microtubule Remodeling Regulates the Collateral Branching of Axons

(2012) Jianli Hu et al.   CURRENT BIOLOGY

Regulation of Microtubule Stability and Organization by Mammalian Par3 in Specifying Neuronal Polarity

(2012) She Chen et al.   DEVELOPMENTAL CELL

N-cadherin specifies first asymmetry in developing neurons

(2012) Annette Gärtner et al.   EMBO JOURNAL

A novel split kinesin assay identifies motor proteins that interact with distinct vesicle populations

(2012) Brian Jenkins et al.   JOURNAL OF CELL BIOLOGY

Rab33a Mediates Anterograde Vesicular Transport for Membrane Exocytosis and Axon Outgrowth

(2012) H. Nakazawa et al.   JOURNAL OF NEUROSCIENCE

Nerve Growth Factor-Induced Formation of Axonal Filopodia and Collateral Branches Involves the Intra-Axonal Synthesis of Regulators of the Actin-Nucleating Arp2/3 Complex

(2012) M. Spillane et al.   JOURNAL OF NEUROSCIENCE

A Caspase Cascade Regulating Developmental Axon Degeneration

(2012) D. J. Simon et al.   JOURNAL OF NEUROSCIENCE

microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons

(2012) Federico Dajas-Bailador et al.   NATURE NEUROSCIENCE

Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth

(2012) Erik Mire et al.   NATURE NEUROSCIENCE

Golgi Outposts Shape Dendrite Morphology by Functioning as Sites of Acentrosomal Microtubule Nucleation in Neurons

(2012) Kassandra M. Ori-McKenney et al.   NEURON

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Networks of Polarized Actin Filaments in the Axon Initial Segment Provide a Mechanism for Sorting Axonal and Dendritic Proteins

(2012) Kaori Watanabe et al.   Cell Reports

Differential Trafficking of Transport Vesicles Contributes to the Localization of Dendritic Proteins

(2012) Sarmad Al-Bassam et al.   Cell Reports

The cytoskeletal and signaling mechanisms of axon collateral branching

(2011) Gianluca Gallo   Developmental Neurobiology

Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration

(2011) Xiaoyu Li et al.   EMBO JOURNAL

Transsynaptic Activity-Dependent Regulation of Axon Branching and Neurotrophin Expression In Vivo

(2011) A.-A. Calinescu et al.   JOURNAL OF NEUROSCIENCE

Live Imaging of Axon Stretch Growth in Embryonic and Adult Neurons

(2011) Joseph R. Loverde et al.   JOURNAL OF NEUROTRAUMA

Microtubules are organized independently from the centrosome in Drosophila neurons

(2011) Michelle M Nguyen et al.   Neural Development

Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum

(2011) Randal Hand et al.   Neural Development

In Vivo Time-Lapse Imaging and Serial Section Electron Microscopy Reveal Developmental Synaptic Rearrangements

(2011) Jianli Li et al.   NEURON

The Many Faces of Tau

(2011) Meaghan Morris et al.   NEURON

The Oriented Emergence of Axons from Retinal Ganglion Cells Is Directed by Laminin Contact In Vivo

(2011) Owen Randlett et al.   NEURON

Semaphorin3A Regulates Neuronal Polarization by Suppressing Axon Formation and Promoting Dendrite Growth

(2011) Maya Shelly et al.   NEURON

Molecular Motor KIF17 Is Fundamental for Memory and Learning via Differential Support of Synaptic NR2A/2B Levels

(2011) Xiling Yin et al.   NEURON

Phosphorylation of E3 Ligase Smurf1 Switches Its Substrate Preference in Support of Axon Development

(2011) Pei-lin Cheng et al.   NEURON

Adenomatous Polyposis Coli Regulates Axon Arborization and Cytoskeleton Organization via Its N-Terminus

(2011) Youjun Chen et al.   PLoS One

The emerging role of forces in axonal elongation

(2011) Daniel M. Suter et al.   PROGRESS IN NEUROBIOLOGY

Neuronal polarization and the cytoskeleton

(2011) Dorothee Neukirchen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Endocytosis and Endosomes at the Crossroads of Regulating Trafficking of Axon Outgrowth-Modifying Receptors

(2011) Bettina Winckler et al.   TRAFFIC

A Role for Myosin VI in the Localization of Axonal Proteins

(2011) Tommy L. Lewis et al.   PLOS BIOLOGY

TGF-β Signaling Specifies Axons during Brain Development

(2010) Jason J. Yi et al.   CELL

Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites

(2010) Lukas C. Kapitein et al.   CURRENT BIOLOGY

The vertebrate retina: A model for neuronal polarization in vivo

(2010) Owen Randlett et al.   Developmental Neurobiology

Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia

(2010) R. Butler et al.   Disease Models & Mechanisms

Pre-synaptic and post-synaptic neuronal activity supports the axon development of callosal projection neurons during different post-natal periods in the mouse cerebral cortex

(2010) Hidenobu Mizuno et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The centrosome neither persistently leads migration nor determines the site of axonogenesis in migrating neurons in vivo

(2010) Martin Distel et al.   JOURNAL OF CELL BIOLOGY

Nerve Growth Factor Induces Axonal Filopodia through Localized Microdomains of Phosphoinositide 3-Kinase Activity That Drive the Formation of Cytoskeletal Precursors to Filopodia

(2010) A. Ketschek et al.   JOURNAL OF NEUROSCIENCE

Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex

(2010) F. C. de Anda et al.   JOURNAL OF NEUROSCIENCE

The axon initial segment and the maintenance of neuronal polarity

(2010) Matthew N. Rasband   NATURE REVIEWS NEUROSCIENCE

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Role of pre- and postsynaptic activity in thalamocortical axon branching

(2010) A. Yamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local and Long-Range Reciprocal Regulation of cAMP and cGMP in Axon/Dendrite Formation

(2010) M. Shelly et al.   SCIENCE

Establishment of Axon-Dendrite Polarity in Developing Neurons

(2009) Anthony P. Barnes et al.   Annual Review of Neuroscience

A Selective Filter for Cytoplasmic Transport at the Axon Initial Segment

(2009) Ai-hong Song et al.   CELL

Growth cone-like waves transport actin and promote axonogenesis and neurite branching

(2009) Kevin C. Flynn et al.   Developmental Neurobiology

Doublecortin Associates with Microtubules Preferentially in Regions of the Axon Displaying Actin-Rich Protrusive Structures

(2009) I. Tint et al.   JOURNAL OF NEUROSCIENCE

Control of Cortical Axon Elongation by a GABA-Driven Ca2+/Calmodulin-Dependent Protein Kinase Cascade

(2009) N. Ageta-Ishihara et al.   JOURNAL OF NEUROSCIENCE

Basic Fibroblast Growth Factor Elicits Formation of Interstitial Axonal Branches via Enhanced Severing of Microtubules

(2009) Liang Qiang et al.   MOLECULAR BIOLOGY OF THE CELL

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

(2009) Tommy L Lewis et al.   NATURE NEUROSCIENCE

The Adenomatous Polyposis Coli Protein Is an Essential Regulator of Radial Glial Polarity and Construction of the Cerebral Cortex

(2009) Yukako Yokota et al.   NEURON

Understanding the Mechanisms of Callosal Development Through the Use of Transgenic Mouse Models

(2009) Amber-Lee S. Donahoo et al.   Seminars in Pediatric Neurology

Neurite consolidation is an active process requiring constant repression of protrusive activity

(2008) Ana Mingorance-Le Meur et al.   EMBO JOURNAL

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

(2008) Kristian L. Hedstrom et al.   JOURNAL OF CELL BIOLOGY

Microtubule stabilization specifies initial neuronal polarization

(2008) Harald Witte et al.   JOURNAL OF CELL BIOLOGY

Role of RhoA in Activity-Dependent Cortical Axon Branching

(2008) S. Ohnami et al.   JOURNAL OF NEUROSCIENCE

Arp2/3 Complex Is Important for Filopodia Formation, Growth Cone Motility, and Neuritogenesis in Neuronal Cells

(2008) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubules Have Opposite Orientation in Axons and Dendrites of Drosophila Neurons

(2008) Michelle C. Stone et al.   MOLECULAR BIOLOGY OF THE CELL

The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches

(2008) Wenqian Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons

(2008) Yi Zheng et al.   NATURE CELL BIOLOGY

Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis

(2008) Sara Geraldo et al.   NATURE CELL BIOLOGY

Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration

(2008) Karun K Singh et al.   NATURE NEUROSCIENCE

Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex

(2008) L. K. Low et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA