ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

(2011) Moritz Marcinowski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanics of Hsp70 chaperones enables differential interaction with client proteins

(2011) Rainer Schlecht et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Endoplasmic Reticulum Overcrowding as a Mechanism of β-Cell Dysfunction in Diabetes

(2010) F. Despa   BIOPHYSICAL JOURNAL

Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells

(2010) Yukio Kimata et al.   CURRENT OPINION IN CELL BIOLOGY

Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation

(2009) Christian Dölle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes

(2009) Chih-Chi Andrew Hu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Divergent Effects of PERK and IRE1 Signaling on Cell Viability

(2009) Jonathan H. Lin et al.   PLoS One

Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

(2009) E. B. Bertelsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Life and death of a BiP substrate

(2009) Joel H. Otero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3

(2008) Kseniya Petrova et al.   EMBO JOURNAL

Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases

(2008) Friedrich Koch-Nolte   Frontiers in Bioscience-Landmark

Rationalizing translation attenuation in the network architecture of the unfolded protein response

(2008) A. Trusina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE