Eukaryotic systems broaden the scope of synthetic biology

Zinc-finger-based artificial transcription factors and their applications

(2009) Takashi Sera   ADVANCED DRUG DELIVERY REVIEWS

Artificial Ribozyme Switches Containing Natural Riboswitch Aptamer Domains

(2009) Markus Wieland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nuclear localization signals and human disease

(2009) Laura M. McLane et al.   IUBMB LIFE

Engineering key components in a synthetic eukaryotic signal transduction pathway

(2009) Mauricio S Antunes et al.   Molecular Systems Biology

Optimized Lentiviral Vector Design Improves Titer and Transgene Expression of Vectors Containing the Chicken β-Globin Locus HS4 Insulator Element

(2009) Hideki Hanawa et al.   MOLECULAR THERAPY

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

A tunable synthetic mammalian oscillator

(2009) Marcel Tigges et al.   NATURE

Diversity-based, model-guided construction of synthetic gene networks with predicted functions

(2009) Tom Ellis et al.   NATURE BIOTECHNOLOGY

Modularity of MAP kinases allows deformation of their signalling pathways

(2009) Areez Mody et al.   NATURE CELL BIOLOGY

The second wave of synthetic biology: from modules to systems

(2009) Priscilla E. M. Purnick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Novel activation domain derived from Che-1 cofactor coupled with the artificial protein Jazz drives utrophin upregulation

(2009) Agata Desantis et al.   NEUROMUSCULAR DISORDERS

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Riboswitches for Enhancing Target Gene Expression in Eukaryotes

(2008) Takahiro Yamauchi et al.   CHEMBIOCHEM

Riboswitches: Ancient and Promising Genetic Regulators

(2008) Simon Blouin et al.   CHEMBIOCHEM

Intron Delays and Transcriptional Timing during Development

(2008) Ian A. Swinburne et al.   DEVELOPMENTAL CELL

Intron length increases oscillatory periods of gene expression in animal cells

(2008) I. A. Swinburne et al.   GENES & DEVELOPMENT

Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene

(2008) Jennifer R. Anthony et al.   METABOLIC ENGINEERING

Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor

(2008) A. S. Beltran et al.   MOLECULAR CANCER THERAPEUTICS

Model-guided design of ligand-regulated RNAi for programmable control of gene expression

(2008) Chase L Beisel et al.   Molecular Systems Biology

Proof-by-synthesis of the transcriptional logic of mammalian circadian clocks

(2008) Maki Ukai-Tadenuma et al.   NATURE CELL BIOLOGY

Engineering GPCR signaling pathways with RASSLs

(2008) Bruce R Conklin et al.   NATURE METHODS

Unexpected failure rates for modular assembly of engineered zinc fingers

(2008) Cherie L Ramirez et al.   NATURE METHODS

Cultivating plant synthetic biology from systems biology

(2008) Tessa A. Bowen et al.   NEW PHYTOLOGIST

Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch

(2008) D. Greber et al.   NUCLEIC ACIDS RESEARCH

A synthetic mammalian gene circuit reveals antituberculosis compounds

(2008) W. Weber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

(2008) C. J. Bashor et al.   SCIENCE

Higher-Order Cellular Information Processing with Synthetic RNA Devices

(2008) M. N. Win et al.   SCIENCE

Local regulation of mRNA translation: new insights from the bud

(2008) Nicolas Paquin et al.   TRENDS IN CELL BIOLOGY

Gene transfer: the challenge of regulated gene expression

(2008) Z. Sheng Guo et al.   TRENDS IN MOLECULAR MEDICINE

Engineering bacteria to solve the Burnt Pancake Problem

(2008) Karmella A Haynes et al.   Journal of Biological Engineering