Article
Biotechnology & Applied Microbiology
Shuling Ye, Chenhong Bao, Yulei Chen, Meixiao Shen, Fan Lu, Shaodan Zhang, Dexi Zhu
Summary: This study describes a non-contact DAS-OCT system that effectively identifies the presence of peripheral anterior synechia (PAS) in angle closure glaucoma patients by measuring the changes of the anterior chamber angle (ACA). The system shows great potential for guiding the diagnosis of angle closure glaucoma.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Review
Medicine, General & Internal
Ahmed A. Abdelghany, Francesco D'Oria, Jorge Alio Del Barrio, Jorge L. Alio
Summary: AS-OCT is a non-contact imaging technique that provides qualitative and quantitative information for clinicians, aiding in the assessment and management of eye diseases such as corneal infections.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Yanling Dong, Dongfang Li, Zhen Guo, Yang Liu, Ping Lin, Bin Lv, Chuanfeng Lv, Guotong Xie, Lixin Xie
Summary: A deep learning based corneal segmentation algorithm was used to accurately delineate corneal tissues and successfully characterize changes in epithelial and corneal thickness at different stages of keratoconus (KC) progression based on AS-OCT images. Thickness gradually decreased with KC progression, with more pronounced trends around the pupil center and a slight shift towards the temporal and inferior side. Epithelial thickness gradually decreased from normal eyes to severe KC. In scarring KC, epithelial thickness showed irregular fluctuations.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Juan Gros-Otero, Samira Ketabi, Rafael Canones-Zafra, Montserrat Garcia-Gonzalez, Cesar Villa-Collar, Santiago Casado, Miguel A. Teus
Summary: The study compared the corneal stromal bed roughness after LASIK flap creation using atomic force microscopy (AFM) with IntraLase 60 kHz and VisuMax femtosecond laser platforms. Results showed a significant difference in surface smoothness between the two laser platforms, with VisuMax creating a smoother stromal bed surface compared to IntraLase.
Article
Ophthalmology
Weam Abdeen, Amanne F. Esmael, Ghada Gawdat, Dina El-Fayoumi
Summary: The study used HH AS-OCT to examine ACA structures and parameters in PCG and normal infant eyes, finding that PCG infants had larger ACA width, reduced IT, and lower identification rates of TM and SC. Abnormal structures, anterior iris insertion, and iridotrabeculodysgenesis were observed in PCG eyes.
Article
Multidisciplinary Sciences
Yu-Chi Liu, Fernando Morales-Wong, Moushmi Patil, Sang Beom Han, Nyein C. Lwin, Ericia Pei Wen Teo, Heng Pei Ang, Nur Zah M. Yussof, Jodhbir S. Mehta
Summary: In femtosecond laser-assisted keratoplasty, a liquid interface is preferred over a flat interface for better control of intraocular pressure, reduced corneal endothelial damage, and more precise laser cutting.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Michal Dembski, Anna Nowinska, Klaudia Ulfik-Dembska, Edward Wylegala
Summary: This study used SS-OCT to determine the mean reference values of anterior segment parameters in healthy Caucasian individuals, finding significant differences between sexes. Parameters of the cornea were found to differ significantly between males and females, with the iridocorneal angle being smallest in the upper quadrant.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Ophthalmology
Jeewan S. Titiyal, Manpreet Kaur, Sridevi Nair, Namrata Sharma
Summary: Intraoperative optical coherence tomography (iOCT) provides real-time visualization of ocular structures during surgery, aiding in decision-making and guidance for various anterior segment surgeries. Its efficacy and feasibility have been well established, particularly in lamellar keratoplasty and endothelial keratoplasty. iOCT also has applications in phacoemulsification, glaucoma surgeries, and pediatric patients, while ongoing technological advances aim to improve limitations related to instrument compatibility and real-time image analysis.
SURVEY OF OPHTHALMOLOGY
(2021)
Article
Medicine, General & Internal
Haruhiro Mori, Yuta Ueno, Shinichi Fukuda, Tetsuro Oshika
Summary: The visibility of anterior hyaloid membrane (AHM) and Berger's space in phakic eyes was investigated. Age and corneal power were significantly associated with AHM visibility. Eyes with visible AHM had a larger refractive error.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Mohammad Abusamak
Summary: This study investigates the mapping characteristics of corneal epithelial thickness (CET) in a Middle Eastern population and its relationship with age, sex, intraocular pressure, and keratometric power (K). The results show that the central CET is thicker than other zones of the cornea, males have thicker CET than females, and there is a positive correlation between age and CET. The findings of this study are important for refractive surgery decision-making and predicting corneal diseases.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Ophthalmology
Stefan Georgiev, Manuel Ruiss, Andreea Dana-Fisus, Rainer A. Leitgeb, Oliver Findl
Summary: This study compared the corneal aberrations measured by two different ophthalmic devices in elderly cataract patients and found that there was a certain agreement between the two devices. However, caution should be exercised when interpreting higher order aberration parameters for surgical decision-making.
Article
Medicine, General & Internal
Naoya Yoshihara, Hiroto Terasaki, Hideki Shiihara, Ryoh Funatsu, Takehiro Yamashita, Taiji Sakamoto
Summary: This study aimed to objectively and quantitatively evaluate the degree of particle density in the anterior chamber after laser iridotomy (LI) using anterior segment optical coherence tomography (AS-OCT). The researchers successfully quantified the accumulation of anterior chamber particles by analyzing AS-OCT images. They found that this simple and repeatable technique can non-invasively and objectively evaluate particles in the anterior chamber, including inflammatory cells.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Seoyoung Wy, Young In Shin, Young Kook Kim, Jin Wook Jeoung, Ki Ho Park
Summary: By using AS-OCT, we investigated the morphology of filtration blebs after XEN gel stent implantation and identified factors related to intraocular pressure (IOP) postoperatively. Analysis showed that a larger height of the internal cavity of the bleb was associated with lower IOP after XEN implantation.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Hiroshi Keino, Takuto Aman, Ryota Furuya, Makiko Nakayama, Annabelle A. Okada, Wataru Sunayama, Yuji Hatanaka
Summary: This study aimed to develop an automated method for evaluating anterior chamber (AC) cells in uveitis using optical coherence tomography (OCT) images. By analyzing the images with software and an automated algorithm, approximate AC grading values were obtained based on the correlation with Standardization of Uveitis Nomenclature (SUN) grading scores. The results showed significant correlations between the automated cellular spots analysis and the clinical scores, providing continuous AC grading values. This method improves the accuracy of quantitative assessment and allows objective and rapid evaluation of anterior segment inflammation in uveitis.
Article
Engineering, Biomedical
Yoel Garcia Marin, Marta Skrok, Damian Siedlecki, Stephen J. Vincent, Michael J. Collins, David Alonso-Caneiro
Summary: This study presents an algorithm based on graph-search theory and boundary-specific image transformation for segmenting anterior segment OCT images, demonstrating reliable extraction of clinically relevant parameters with high agreement with manual segmentation.
BIOCYBERNETICS AND BIOMEDICAL ENGINEERING
(2021)
Article
Ophthalmology
C. Lwowski, T. Kohnen
Article
Ophthalmology
Petra P. Larsen, Sarah Thiele, Tim U. Krohne, Focke Ziemssen, Frank Krummenauer, Frank G. Holz, Robert P. Finger, Thomas Kohnen, Lubka Naycheva, Maximilian Jochem, Thomas Reinhard, Daniel Boehringer, Diana Engesser, Wolf Lagreze, Claudia Mueller, Carolin Wolff, Jessica Schmitz, Birgit Lorenz, Chrysanthi Papadopoulou-Laiou, Kerstin Holve, Silke Schweinfurth, Hans Hoerauf, Wiebke Schwarz, Martin Spitzer, Lars Wagenfeld, Paul Bertram, Gerd Auffarth, Branka Gavrilovic, Claus Cursiefen, Friederike Schaub, Anna Lentzsch, Gerhard Welsandt, Hagen Thieme, Melanie Weigel, Diyala Hidaya, Angela Ehmer, Siegfried Priglinger, Bettina von Livonius, Carina Drexler, Jessica Semmelsberger, Nicole Eter, Florian Alten, Annika Sigleur, Dorothee Sieber, Andrea Braeutigam, Friederike Haerter, Adeline Adorf, Daniel Pauleikhoff, Angela Robering, Horst Helbig, Caroline Brandl, Focke Ziemssen, Daniel Roeck, Frank Krummenauer, Sabrina Tulka, Bettina Wabbels, David. G. Kupitz, Arno P. Goebel, Julia Steinberg, Petra P. Larsen, Anne Schnetzer, Bianka Kobialka, Beate Prinz, Danielle Kutten, Pia Schneider, Olivia Toczko, Thanushiya Yoganathan
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
D. Boehringer, D. Goos, T. Ach, N. Feltgen, M. Fleckenstein, T. Kohnen, K. Lorenz, A. Pielen, G. Spital, B. Wilhelm, S. Boehringer, T. Reinhard
Article
Ophthalmology
Thomas Kohnen, Myriam Boehm, Eva Hemkeppler, Sabrina Schoenbrunn, Nina DeLorenzo, Kerstin Petermann, Michael Herzog
Article
Ophthalmology
Lixin Wang, Patricia Wolfe, Sumit Paliwal, Alexis Chernosky, Thomas Kohnen
Summary: In this study using an in vitro human cadaver eye model, the new preloaded delivery system for intraocular lens implantation showed comparable corneal incision enlargement performance to the standard-of-care manual delivery system, despite having a smaller initial incision size. This suggests that smaller incision sizes for cataract surgery can improve patient outcomes through faster visual and wound recovery, and reduced risk of complications.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Editorial Material
Ophthalmology
Thomas Kohnen
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2019)
Article
Ophthalmology
Thomas Kohnen, Franziska Loeffler, Michael Herzog, Kerstin Petermann, Myriam Boehm
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2019)
Article
Ophthalmology
Myriam Boehm, Kerstin Petermann, Eva Hemkeppler, Thomas Kohnen
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2019)
Article
Environmental Sciences
Ulrike Scheidemann-Wesp, Emilio A. L. Gianicolo, Rafael J. Camara, Alfred Wegener, Sabine E. Buchner, Oliver Schwenn, Andrea Hoeck, Harald Buchner, Katrin Lorenz, Urs Vossmerbaeumer, Myriam Boehm, Thomas Kohnen, Daniel Wollschlaeger, Susanne Singer, Maria Blettner, Gael P. Hammer
JOURNAL OF RADIOLOGICAL PROTECTION
(2019)
Article
Ophthalmology
Svenja Deuchler, Clemens Wagner, Markus Schill, Benjamin Schoene, Daniel Scherer, Pankaj Singh, Thomas Kohnen, Frank H. J. Koch
CASE REPORTS IN OPHTHALMOLOGY
(2019)
Meeting Abstract
Ophthalmology
Ingo Schmack, Bishr Agha, Daniel G. Dawson, Thomas Kohnen
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2019)
Meeting Abstract
Ophthalmology
Myriam Susanne Boehm, Kerstin Petermann, Eva Hemkeppler, Thomas Kohnen
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2019)
Meeting Abstract
Ophthalmology
Juliane Tittes, Alexander Baldwin, Peggy Feige, Licia Cirina, Yaroslava Wenner, Claudia Kuhli-Hattenbach, Hanns Ackermann, Robert Hess, Thomas Kohnen, Maria Fronius
Article
Ophthalmology
Bishr Agha, Mehdi Shajari, Anna Slavik-Lencova, Thomas Kohnen, Ingo Schmack
CLINICAL OPHTHALMOLOGY
(2019)
Article
Ophthalmology
Bishr Agha, Mehdi Shajari, Anna Slavik-Lencova, Thomas Kohnen, Ingo Schmack
CLINICAL OPHTHALMOLOGY
(2019)