Article
Medicine, General & Internal
Armin Luik, Kerstin Schmidt, Annika Haas, Laura Unger, Panagiotis Tzamalis, Bernd Brueggenjuergen
Summary: The treatment of atrial tachycardia following catheter ablation of atrial fibrillation is often challenging, but new ablation approaches have shown promising results. However, long-term data on the freedom from any atrial tachycardia or any arrhythmia are still limited. This study presents 12-month success and mean 30 month follow-up data of catheter ablation of left atrial tachycardia, demonstrating high long-term clinical success rates with individual ablation strategies.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Janis Pongratz, Uwe Dorwarth, Lukas Riess, Yitzhack Schwartz, Michael Wankerl, Ellen Hoffmann, Florian Straube
Summary: This study evaluated the feasibility and safety of a novel three-dimensional wide-band dielectric imaging system (3D-WBDIS) in guiding cryoballoon ablation (CBA) and optional radiofrequency ablation (RFA) in patients with complex atrial arrhythmias (AA). The results showed that the 3D-WBDIS had high sensitivity and specificity in assessing balloon occlusion, and additional arrhythmias were successfully mapped and ablated. The short-term outcome was promising.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Li Luo, Zuoan Qin, Ruizheng Shi, Liangqing Ge
Summary: Catheter ablation for atrial tachycardia originating from the right atrial appendage may have a high failure rate, but thoracoscopic clamp radiofrequency ablation appears to be a reasonable alternative, especially for young patients. This case report demonstrated successful treatment outcomes in restoring normal sinus rhythm and heart structure for a young patient with incessant tachycardia.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jien-Jiun Chen, Fu-Chun Chiu, Sheng-Nan Chang, Hsiao-Liang Cheng, Pang-shuo Huang, Cho-Kai Wu, Yi-Chih Wang, Juey-Jen Hwang, Chia-Ti Tsai
Summary: This pioneer study investigated the impact of pre-existing left atrial appendage occluder (LAAO) on atrial fibrillation (AF) substrates and outcomes of pulmonary vein isolation (PVI). Results showed that LAAO may modulate left atrial substrate and induce peridevice fibrosis, peridevice left atrial flutter, and complex fractionate atrial electrogram.
Article
Cardiac & Cardiovascular Systems
Ann-Kathrin Kahle, Roberto G. Gallotti, Fares-Alexander Alken, Christian Meyer, Jeremy P. Moore
Summary: Ultra-high-density mapping-guided CV analysis can distinguish atrial reentrant patterns in adults with congenital heart disease, with surgical obstacles producing slower and smaller circuits. Very slow central isthmus CV may be essential for atrial tachycardia maintenance in small circuits, and non-isthmus conduction time in tachycardia appears to be useful for rapid assessment of postablation conduction block.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Dony Yugo, Yun-Yu Chen, Yenn-Jiang Lin, Kuo-Liong Chien, Shih-Lin Chang, Li-Wei Lo, Yu-Feng Hu, Tze-Fan Chao, Fa-Po Chung, Jo-Nan Liao, Ting-Yung Chang, Chin-Yu Lin, Ta-Chuan Tuan, Ling Kuo, Cheng- Wu, Chih-Min Liu, Shin-Huei Liu, Cheng-Hung Li, Yu-Cheng Hsieh, Shih-Ann Chen
Summary: This study compared the long-term outcomes of patients with atrial flutter (AFL) who received catheter ablation versus medical therapy, finding that catheter ablation was associated with lower risks of all-cause mortality and cardiovascular events during long-term follow-ups.
Article
Cardiac & Cardiovascular Systems
Stepan Havranek, Zdenka Fingrova, Tomas Skala, Adrian Reichenbach, Milan Dusik, Pavel Jansa, David Ambroz, Vladimir Dytrych, Dalibor Klimes, Martin Hutyra, Josef Kautzner, Ales Linhart, Dan Wichterle
Summary: This study aimed to investigate whether more extensive radiofrequency catheter ablation of the bi-atrial arrhythmogenic substrate instead of clinical arrhythmia ablation alone results in superior clinical outcomes in patients with pulmonary arterial hypertension (PH) and supraventricular arrhythmias. The results showed similar arrhythmia recurrence rates between the two treatment groups, and no excess of procedural complications or clinical events in the extensive ablation group.
Article
Health Care Sciences & Services
Felix K. Wegner, Robert M. Radke, Christian Ellermann, Julian Wolfes, Kevin Willy, Philipp S. Lange, Gerrit Frommeyer, Helmut Baumgartner, Lars Eckardt, Gerhard-Paul Diller, Stefan Orwat
Summary: Introduction: Transesophageal echocardiography (TEE) is routinely performed before catheter ablation of atrial tachyarrhythmias to rule out the presence of left atrial thrombi. However, data to support this practice are inconsistent. The study analyzed consecutive pre-procedural TEE to determine the presence of left atrial thrombi and relevant flow reduction in the left atrial appendage (LAA). The underlying rhythm and kidney function were found to be predictors of reduced LAA flow.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
F. Daniel Ramirez, Marianna Meo, Corentin Dallet, Philipp Krisai, Konstantinos Vlachos, Antonio Frontera, Masateru Takigawa, Yosuke Nakatani, Takashi Nakashima, Clementine Andre, Tsukasa Kamakura, Takamitsu Takagi, Aline Carapezzi, Romain Tixier, Remi Chauvel, Ghassen Cheniti, Josselin Duchateau, Thomas Pambrun, Frederic Sacher, Mfileze Hocini, Michel Haissaguerre, Pierre Jais, Remi Dubois, Nicolas Derval
Summary: This study aimed to evaluate the diagnostic performance of bipolar voltage thresholds in identifying regions of slow conduction during reentrant atrial tachycardias. The results showed that bipolar voltage can predict regions of slow conduction, but the correlation between voltage and conduction velocity is modest. Furthermore, no clinical predictors of AT circuit dimensions were identified.
Review
Cardiac & Cardiovascular Systems
Poojesh Nikhil Lallah, Chen Laite, Abdul Basit Bangash, Outesh Chooah, Chenyang Jiang
Summary: Catheter ablation is an effective method for treating cardiac arrhythmias, but there is a risk of recurrence. Artificial intelligence (AI) can be used to predict and identify arrhythmias based on clinical variables, electrophysiological characteristics, and imaging data. AI has shown promising outcomes, but research on predicting atrial flutter and atrial tachycardia recurrence is limited.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Victor Waldmann, Joachim Hebe, Edward P. Walsh, Paul Khairy, Sabine Ernst
Summary: Catheter ablation of AV nodal reentrant tachycardia in congenital heart disease is challenging, and deferring ablation may be a wise approach in selected patients with complex cases.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Anna N. Kamp, Krishnakumar Nair, Frank A. Fish, Paul Khairy
Summary: Atrial arrhythmias are common in the aging Fontan population and have a significant impact on morbidity and mortality. The most common type of arrhythmia is scar-based intra-atrial re-entrant tachycardia, but other types of arrhythmias may also occur. A multifaceted approach to management, including anticoagulation, anti-arrhythmic drug therapy, pacing, and cardioversion, is often necessary. Careful consideration of various factors, such as clinical burden, ventricular function, and hemodynamic stability, is important in decision-making.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Roberto De Ponti, Raffaella Marazzi, Manola Vilotta, Fabio Angeli, Jacopo Marazzato
Summary: This review provides an overview of the clinical settings in which atypical atrial flutters (AAFL) may occur and aims to predict the location of tachycardia circuits before radiofrequency catheter ablation (CA). The study finds that CA of AAFL is generally feasible, but the long-term success rate may be lower in specific clinical settings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jing Liu, Xiaoxiao Cao, Changjian Li, Xiaoyuan Feng, Dongming Sun, Yong Zhang
Summary: This study investigated the efficacy of RFCA combined with AA resection in treating children with AT originating from the AA. The study found that the ECG characteristics can be used to diagnose AT originating from the AA. AA resection was proven to be an effective treatment for children who were not successfully controlled by RFCA or who had a recurrence after RFCA.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Shingo Maeda, Masahiko Goya, Yasuhiro Shirai, Atsuhiko Yagishita, Susumu Tao, Jackson Jeikai Liang, Ruben Casado Arroyo, Yoshihide Takahashi, Mihoko Kawabata, Tetsuo Sasano, Kenzo Hirao
Summary: This study aimed to identify novel predictors of effective atrial anti-tachycardia pacing (A-ATP) for terminating atrial fibrillation (AF) in patients undergoing catheter ablation. The results showed that simultaneous biatrial A-ATP from the right atrium (RA) and coronary sinus (CS) could terminate AF in patients with paroxysmal AF. The predictors for successful termination included longer AF cycle length and higher AF stability.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
David E. Haines, Melissa H. Kong, Peter Ruppersberg, Philip Haeusser, Boaz Avitall, Tamas Szili Torok, Atul Verma
Summary: Ablation strategies are still unclear for persistent atrial fibrillation patients who experience recurrence despite intact pulmonary vein isolation. Advanced mapping techniques that can identify extra-pulmonary vein sources of atrial fibrillation are increasingly necessary as the ability to perform durable pulmonary vein isolation improves. Electrographic flow mapping provides a novel method for mapping atrial fibrillation by reconstructing organized wavefront propagation within chaotic electrical conduction. This paper explains the technical and mathematical foundations of electrographic flow mapping and demonstrates its clinical applications.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Stefan G. Spitzer, John M. Miller, Philipp Sommer, Tamas Szili-Torok, Vivek Y. Reddy, Georg Noelker, Chris Williams, Anne Sarver, David J. Wilber
Summary: The REDO-FIRM study evaluated the safety and effectiveness of conventional and FIRM-guided ablation in patients with recurrent atrial fibrillation. The study found that while FIRM-guided ablation did not provide additional efficacy, it was equally safe.
Article
Respiratory System
Marc Humbert, Gabor Kovacs, Marius M. Hoeper, Roberto Badagliacca, Rolf M. F. Berger, Margarita Brida, Jorn Carlsen, Andrew J. S. Coats, Pilar Escribano-Subias, Pisana Ferrari, Diogenes S. Ferreira, Hossein Ardeschir Ghofrani, George Giannakoulas, David G. Kiely, Eckhard Mayer, Gergely Meszaros, Blin Nagavci, Karen M. Olsson, Joanna Pepke-Zaba, Jennifer K. Quint, Goran Radegran, Gerald Simonneau, Olivier Sitbon, Thomy Tonia, Mark Toshner, Jean Luc Vachiery, Anton Vonk Noordegraaf, Marion Delcroix, Stephan Rosenkranz
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Rita B. Gagyi, Anna M. E. Noten, Krista Lesina, Bakhtawar K. Mahmoodi, Sing-Chien Yap, Mark G. Hoogendijk, Sip Wijchers, Rohit E. Bhagwandien, Tamas Szili-Torok
Summary: The novel dipole charge density-based high-resolution mapping technique (AcQMap) has been proven to have significant value in treating brief episodes of atrial tachycardia and premature atrial contractions (PACs), with high accuracy and success rates.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Clinical Neurology
Elena Herber, Stefanie Aeschbacher, Michael Coslovsky, Fabian Schwendinger, Elisa Hennings, Andreas Gasser, Marcello Di Valentino, Elia Rigamonti, Tobias Reichlin, Nicolas Rodondi, Seraina Netzer, Juerg H. Beer, Annina Stauber, Andreas Mueller, Peter Ammann, Tim Sinnecker, Marco Duering, Jens Wuerfel, David Conen, Michael Kuhne, Stefan Osswald, Leo H. Bonati
Summary: This study found that regular exercise in patients with atrial fibrillation can reduce the prevalence of ischemic infarcts and white matter lesions, increase brain volume, and improve cognitive performance. Therefore, it is recommended that patients with atrial fibrillation actively participate in physical exercise.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Engineering, Biomedical
Amira Assaf, Dominic A. M. J. Theuns, Michelle Michels, Jolien Roos-Hesselink, Tamas Szili-Torok, Sing-Chien Yap
Summary: The 2018 ESC Syncope guidelines expanded the indications for an insertable cardiac monitor (ICM) to include patients with unexplained syncope and primary cardiomyopathy or inheritable arrhythmogenic disorders. This review article discusses the clinical evidence for using an ICM for risk stratification in different patient populations, including various cardiac conditions. The experts suggest that while there is limited data on the usefulness of ICMs in these populations, most studies demonstrate its early detection of clinically relevant arrhythmias. However, the impact of ICMs on prognosis is difficult to demonstrate in populations with rare diseases.
EXPERT REVIEW OF MEDICAL DEVICES
(2023)
Article
Cardiac & Cardiovascular Systems
Marco Luciani, Daniel Mueller, Chiara Vanetta, Thamonwan Diteepeng, Arnold von Eckardstein, Stefanie Aeschbacher, Nicolas Rodondi, Giorgio Moschovitis, Tobias Reichlin, Tim Sinnecker, Jens Wuerfel, Leo H. Bonati, Seyed Soheil Saeedi Saravi, Patricia Chocano-Bedoya, Michael Coslovsky, Giovanni G. Camici, Thomas F. Luescher, Michael Kuehne, Stefan Osswald, David Conen, Juerg Hans Beer
Summary: This study investigated the role of trimethylamine-N-oxide (TMAO) in predicting adverse events in patients with atrial fibrillation. The results showed that high levels of TMAO are associated with increased risk of cardiovascular mortality and cerebral infarction.
Article
Cardiac & Cardiovascular Systems
Thomas Kueffer, Andreas Haeberlin, Sven Knecht, Samuel H. Baldinger, Antonio Madaffari, Jens Seiler, Aline Muehl, Hildegard Tanner, Laurent Roten, Tobias Reichlin
Summary: This study aims to compare the accuracy and reproducibility of four different force sensing ablation catheters. The results show that the contact force measured by these catheters deviates by 1-3 g from the actual force within the range of 10-40 g. However, significant errors can occur at higher forces, potentially impacting clinical outcomes.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Article
Psychiatry
Christina M. Andersen, Jens Brock Johansen, Sonja Wehberg, Jens Cosedis Nielsen, Sam Riahi, Jens Haarbo, Berit T. Philbert, Susanne S. Pedersen, DEFIB WOMEN Investigators
Summary: The study found that female patients scored higher on ICD concerns compared to male patients, but both sexes experienced a decrease in ICD concerns in the first 6 months post-implantation. ICD shocks, anxiety, depression, and baseline ICD concerns were predictors of patient's ICD concerns at the 24-month follow-up.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Clinical Neurology
Thomas R. Meinel, Duncan Wilson, Henrik Gensicke, Jan F. Scheitz, Peter Ringleb, Ioana Goganau, Johannes Kaesmacher, Hee-Joon Bae, Do Yeon Kim, Pawel Kermer, Kentaro Suzuki, Kazumi Kimura, Kosmas Macha, Masatoshi Koga, Shinishi Wada, Valerian Altersberger, Alexander Salerno, Logesh Palanikumar, Andrea Zini, Stefano Forlivesi, Lars Kellert, Johannes Wischmann, Espen Kristoffersen, James Beharry, P. Alan Barber, Jae Beom Hong, Carlo Cereda, Eckhard Schlemm, Yusuke Yakushiji, Sven Poli, Ronen Leker, Michele Romoli, Marialuisa Zedde, Sami Curtze, Benno Ikenberg, Timo Uphaus, David Giannandrea, Pere Cardona Portela, Roland Veltkamp, Annemarei Ranta, Marcel Arnold, Urs Fischer, Jae-Kwan Cha, Teddy Y. Wu, Jan C. Purrucker, David J. Seiffge
Summary: This study aimed to determine the risk of symptomatic intracranial hemorrhage (sICH) associated with the use of intravenous thrombolysis (IVT) in patients with recent intake of direct oral anticoagulants (DOACs) after ischemic stroke. The findings suggest that there is no excessive harm associated with off-label IVT in selected patients after ischemic stroke with recent DOAC ingestion.
Article
Cardiac & Cardiovascular Systems
Rita B. Gagyi, Rohit E. Bhagwandien, Sing-Chien Yap, Mark Hoogendijk, Sip Wijchers, Tamas Szili-Torok
Summary: This study compared the efficacy of electrographic flow (EGF) guided ablation with empiric ablation in the treatment of persistent atrial fibrillation. The results showed that EGF-guided ablation led to fewer AF recurrences at 12 months. Despite longer procedure times, it was safe and offered a more targeted, patient-specific ablation strategy for this complex group of patients.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Camilla H. B. Jespersen, Johanna Kroll, Priya Bhardwaj, Carl Johann Hansen, Jesper Svane, Bo G. G. Winkel, Christian Jons, Peter Karl Jacobsen, Jens Haarbo, Jens Cosedis Nielsen, Jens Brock Johansen, Berit T. T. Philbert, Sam Riahi, Christian Torp-Pedersen, Lars Kober, Jacob Tfelt Hansen, Peter E. E. Weeke
Summary: One in 3 patients with Brugada syndrome were treated with a nonrecommended drug after diagnosis. Factors associated with nonrecommended drug use include gender, psychiatric disease, and prior use of nonrecommended BrS drugs. More awareness of nonrecommended drug use among BrS patients is needed.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Letter
Cardiac & Cardiovascular Systems
Jawad H. Butt, Adelina Yafasova, Seiko N. Doi, Jens C. Nielsen, Jens Haarbo, Hans Eiskjaer, Axel Brandes, Anna M. Thogersen, Finn Gustafsson, Christian Hassager, Jesper H. Svendsen, Dan E. Hofsten, Lars Videbaek, Christian Torp-Pedersen, Steen Pehrson, Jens Jakob Thune, Lars Kober
Letter
Cardiac & Cardiovascular Systems
Seiko Nakajima Doi, Jens Jakob Thune, Jens Cosedis Nielsen, Jens Haarbo, Lars Videbaek, Rasmus Rorth, Soren Lund Kristensen, Niels Eske Bruun, Finn Gustafsson, Hans Eiskjaer, Christian Hassager, Jesper Hastrup Svendsen, Dan Eik Hofsten, Christian Torp-Pedersen, Steen Pehrson, Lars Kober, Jawad Haider Butt
CIRCULATION-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Khalil Mahmoudi, Roberto Galea, Simon Elhadad, Fabrice Temperli, Frederic Sebag, Christoph Grani, Zhor Rezine, Laurent Roten, Nicolas Brugger, Quentin Landolff, Alaa Masri, Lorenz Raber, Nicolas Amabile
Summary: This study analyzed the impact of Watchman device implantation on left atrial appendage dimensions and found that the dimensions significantly increased after implantation, especially in patients with oversized devices.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)