Article
Anesthesiology
Olga de la Varga-Martinez, Estefania Gomez-Pesquera, Maria Fe Munoz-Moreno, Jose Miguel Marcos-Vidal, Amparo Lopez-Gomez, Frederic Rodenas-Gomez, Fernando Ramasco, Felisa Alvarez-Refojo, Eduardo Tamayo, Esther Gomez-Sanchez
Summary: The study developed and validated a preoperative delirium risk prediction model for patients undergoing cardiac surgery, consisting of four well-defined clinical risk factors: age, cognitive status, sleep, and physical activity. The model showed good predictive accuracy and can stratify patients into different risk groups with corresponding positive and negative predictive values.
JOURNAL OF CLINICAL ANESTHESIA
(2021)
Article
Geriatrics & Gerontology
Tamara G. Fong, Jason A. Albaum, Molly L. Anderson, Sara G. Cohen, Shauni Johnson, Mark A. Supiano, Philip E. Vlisides, Harley L. Wade, Lyn Weinberg, Heidi R. Wierman, Wendy Zachary, Sharon K. Inouye
Summary: The study team developed a modified version of the Hospital Elder Life Program (HELP-ME) for remote and/or physically distanced applications to prevent delirium. HELP-ME was fully implemented at four expert sites, achieving an overall adherence rate of 82%. It is recommended to test hybrid approaches and evaluate effectiveness in future work.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Neurosciences
Zhiqiang Chen, Quanshui Hao, Rao Sun, Yanjing Zhang, Hui Fu, Shile Liu, Chenglei Luo, Hanwen Chen, Yiwen Zhang
Summary: The study aimed to investigate the relationship between preoperative geriatric nutritional risk index (GNRI) and postoperative delirium (POD) in elderly patients after cardiac surgery, and to evaluate the additional value of GNRI in predicting POD. Results showed that patients with lower GNRI scores had a higher risk of developing POD. The addition of GNRI improved the predictive accuracy in some models.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Medicine, General & Internal
Zhe Chu, Yixuan Wu, Xuanhui Dai, Cuicui Zhang, Qianfeng He
Summary: This study analyzed the risk factors for postoperative delirium in patients with hip fracture, finding that a history of delirium, diabetes mellitus, hypoxemia, hypoalbuminemia, and low body mass index were independent risk factors. Cutoff values for postoperative blood sugar, albumin, and BMI were identified for predicting delirium occurrence.
Review
Surgery
P. Bramley, K. McArthur, A. Blayney, I. McCullagh
Summary: Postoperative delirium is associated with increased mortality, hospital stays, and cognitive decline. Existing literature presents a wide range of risk factors, but few are validated and no accurate prognostic models exist. Future research should focus on validating existing prognostic models and conducting interventional studies.
INTERNATIONAL JOURNAL OF SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Hongbai Wang, Xiaoxiao Guo, Xianlin Zhu, Yinan Li, Yuan Jia, Zhe Zhang, Su Yuan, Fuxia Yan
Summary: This retrospective case-control study found that male gender is a significant risk factor for postoperative delirium (POD) in patients following cardiac valve surgery, especially in patients aged younger than 60 years. The study also showed that the incidence of hyperactive delirium is higher in males, emphasizing the importance of attention to male patients to prevent POD occurrence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Health Care Sciences & Services
Eleni Spiropoulou, George Samanidis, Meletios Kanakis, Ioannis Nenekidis
Summary: This study found that the incidence of postoperative delirium in the cardiac surgery ICU was 25.6%. Smoking history, alcohol use, chronic obstructive pulmonary disease, and preoperative persistent atrial fibrillation were associated with postoperative delirium. Hypoxemia after extubation, heart rate after extubation, and alcohol use were predictive factors for acute postoperative delirium.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Nursing
Mary Dioise Ramos, Franz Henryk Vergara, Jenna Shackleford, Christina Briggs, Carolina Gomez, Mahdi Mofazali, Jade Preston
Summary: This integrative review aimed to synthesize specific comorbidities that can contribute to the development of post-operative delirium in older adult cardiac surgical patients. The study identified several comorbidities, including diabetes mellitus, atrial fibrillation, depression, impaired olfaction, pre-existing cerebrovascular disease, pre-existing cardiovascular disease, insomnia, and frailty. The results strongly indicated a link between comorbidities and the development of post-operative delirium in older adult cardiac surgical patients.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Cardiac & Cardiovascular Systems
Terezia B. Andrasi, Ildar Talipov, Gerhard Dinges, Christian Arndt, Ardawan J. Rastan
Summary: The study found that postoperative delirium is associated with factors including patient age, surgery time, transfusion, and atrial fibrillation. These associations vary based on different operative characteristics, highlighting the importance of optimizing intraoperative parameters and using risk calculators to improve outcomes after cardiac surgery.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Lingyu Lin, Yanchun Peng, Xizhen Huang, Sailan Li, Liangwan Chen, Yanjuan Lin
Summary: This study aimed to investigate the effects of family intervention on the incidence of postoperative delirium (POD) and ICU prognoses of patients undergoing cardiac valve surgery. The results showed that family intervention could reduce the incidence of POD, shorten ICU stays, reduce the incidence of anxiety and depression in family caregivers, and improve their satisfaction. Therefore, family intervention is of significant importance for patients undergoing cardiac valve surgery.
Article
Critical Care Medicine
Tugce Dinc Dogan, Vera Guttenthaler, Alexa Zimmermann, Andrea Kunsorg, Merve oezlem Dinc, Niko Knuelle, Jens-Christian Schewe, Maria Wittmann
Summary: The study suggests that multisensory stimulation performed in the first three days after planned cardiac surgery can reduce the incidence and duration of postoperative delirium in older patients. Further clinical studies are needed to confirm the treatment's effects on the incidence of delirium in other patient groups, length of stay in the intensive care unit, and postoperative pain.
JOURNAL OF INTENSIVE CARE
(2023)
Article
Medicine, General & Internal
Jakub Kazmierski, Piotr Miler, Agnieszka Pawlak, Hanna Jerczynska, Karina Nowakowska, Grzegorz Walkiewicz, Katarzyna Wozniak, Michal Krejca, Miroslaw Wilczynski
Summary: This study aims to assess the association between increased pre- and postoperative myeloperoxidase (MPO) levels and postoperative delirium in cardiac surgery patients, as well as the correlation between MPO levels and serum antioxidant capacity (AC). The results showed that increased postoperative MPO concentration is independently associated with postoperative delirium development and negatively correlated with baseline serum AC. This suggests that cardiac surgery patients with less efficient antioxidative mechanisms are more prone to postoperative delirium.
ANNALS OF MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Monika Sadlonova, Jonathan Vogelgsang, Claudia Lange, Irina Guenther, Adriana Wiesent, Charlotte Eberhard, Julia Ehrentraut, Mareike Kirsch, Niels Hansen, Hermann Esselmann, Charles Timaeus, Thomas Asendorf, Benedict Breitling, Mohammed Chebbok, Stephanie Heinemann, Christopher Celano, Ingo Kutschka, Jens Wiltfang, Hassina Baraki, Christine A. F. von Arnim
Summary: This study aims to validate a delirium risk assessment in the context of cardiac surgery and further identify factors associated with delirium, cognitive decline, and dementia. It also aims to identify blood-based biomarkers that can predict the incidence of postoperative delirium, cognitive decline, or dementia in patients undergoing cardiac surgery.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Cardiac & Cardiovascular Systems
Haiyan Chen, Liang Mo, Hongjuan Hu, Yulan Ou, Juan Luo
Summary: This meta-analysis identified several risk factors associated with postoperative delirium after cardiac surgery, such as aging, diabetes, and preoperative depression. Utilizing this information may help in identifying high-risk patients before delirium onset.
JOURNAL OF CARDIOTHORACIC SURGERY
(2021)
Article
Multidisciplinary Sciences
Hohyung Jung, Jihye Lee, Hyun Young Ahn, Jeong Hoon Yang, Gee Young Suh, Ryoung-Eun Ko, Chi Ryang Chung
Summary: Continuous ketamine administration may be a safe and effective analgesic for medical and cardiac ICU patients receiving mechanical ventilation support, reducing opioid usage without adverse hemodynamic effects.