Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth

Atractylodes macrocephala polysaccharides induces mitochondrial-mediated apoptosis in glioma C6 cells

(2014) Xuejun Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Thymoquinone Induces Apoptosis in Oral Cancer Cells Through P38β Inhibition

(2013) Ehab Abdelfadil et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Cytokines from the tumor microenvironment modulate sirtinol cytotoxicity in A549 lung carcinoma cells

(2013) Shyama Pal et al.   CYTOKINE

Anti-inflammatory activity of edible brown alga Eisenia bicyclis and its constituents fucosterol and phlorotannins in LPS-stimulated RAW264.7 macrophages

(2013) Hyun Ah Jung et al.   FOOD AND CHEMICAL TOXICOLOGY

Cytoprotective effect of dieckol on human endothelial progenitor cells (hEPCs) from oxidative stress-induced apoptosis

(2013) S. H. Lee et al.   FREE RADICAL RESEARCH

Antioxidant Activity of Various Solvent Fractions from Edible Brown Alga,Eisenia bicyclisand Its Active Compounds

(2013) Tae-Hyung Kwon et al.   JOURNAL OF FOOD SCIENCE

The role of globular heads of the C1q receptor in HPV 16 E2-induced human cervical squamous carcinoma cell apoptosis is associated with p38 MAPK/JNK activation

(2013) Ling-juan Gao et al.   Journal of Translational Medicine

ROS-Dependent Mitochondria Molecular Mechanisms Underlying Antitumor Activity of Pleurotus abalonus Acidic Polysaccharides in Human Breast Cancer MCF-7 Cells

(2013) Xiaolong Shi et al.   PLoS One

Pomalidomide Shows Significant Therapeutic Activity against CNS Lymphoma with a Major Impact on the Tumor Microenvironment in Murine Models

(2013) Zhimin Li et al.   PLoS One

Biological Activities and Bioavailability of Mangosteen Xanthones: A Critical Review of the Current Evidence

(2013) Fabiola Gutierrez-Orozco et al.   Nutrients

Dieckol Isolated fromEcklonia cavaProtects against High-Glucose Induced Damage to Rat Insulinoma Cells by Reducing Oxidative Stress and Apoptosis

(2012) Seung-Hong LEE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Tetrathiomolybdate sensitizes ovarian cancer cells to anticancer drugs doxorubicin, fenretinide, 5-fluorouracil and mitomycin C

(2012) Kyu Kwang Kim et al.   BMC CANCER

6,6′-Bieckol, isolated from marine alga Ecklonia cava, suppressed LPS-induced nitric oxide and PGE2 production and inflammatory cytokine expression in macrophages: The inhibition of NFκB

(2012) Yeong-In Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of Ecklonia cava Polyphenol in Individuals with Hypercholesterolemia: A Pilot Study

(2012) Dong Hyeon Lee et al.   JOURNAL OF MEDICINAL FOOD

Antioxidant dieckol downregulates the Rac1/ROS signaling pathway and inhibits Wiskott-Aldrich syndrome protein (WASP)-family verprolin-homologous protein 2 (WAVE2)-mediated invasive migration of B16 mouse melanoma cells

(2012) Sun Joo Park et al.   MOLECULES AND CELLS

Dieckol from Ecklonia cava suppresses the migration and invasion of HT1080 cells by inhibiting the focal adhesion kinase pathway downstream of Rac1-ROS signaling

(2012) Sun Joo Park et al.   MOLECULES AND CELLS

Overexpression of miR-7-1 Increases Efficacy of Green Tea Polyphenols for Induction of Apoptosis in Human Malignant Neuroblastoma SH-SY5Y and SK-N-DZ Cells

(2012) Mrinmay Chakrabarti et al.   NEUROCHEMICAL RESEARCH

Oral RKS262 reduces tumor burden in a neuroblastoma xenograft animal model and mediates cytotoxicity through SAPK/JNK and ROS activation in vitro

(2011) Rakesh K. Singh et al.   CANCER BIOLOGY & THERAPY

The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cells

(2011) Seung-Hwan Kwon et al.   FOOD AND CHEMICAL TOXICOLOGY

ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation

(2011) Xin Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exploiting biological activities of brown seaweedEcklonia cavafor potential industrial applications: a review

(2011) W. A. J. P. Wijesinghe et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Induction of programmed cell death by inhibition of AKT with the alkylphosphocholine perifosine in in vitro models of platinum sensitive and resistant ovarian cancers

(2010) Jörg B. Engel et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Antitumor and Anti-inflammatory Effects of Trabectedin on Human Myxoid Liposarcoma Cells

(2010) G. Germano et al.   CANCER RESEARCH

Antioxidative effect of Ecklonia cava dried by far infrared radiation drying

(2010) Seung-Hong Lee et al.   FOOD SCIENCE AND BIOTECHNOLOGY

The pharmacological NFκB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

(2009) Alfeu Zanotto-Filho et al.   CANCER LETTERS

Prevention of paclitaxel and cisplatin induced ovarian damage in rats by a gonadotropin-releasing hormone agonist

(2009) Bulent Ozcelik et al.   FERTILITY AND STERILITY

Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells

(2009) Chang-Suk Kong et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibitory Effects and Molecular Mechanism of Dieckol Isolated from Marine Brown Alga on COX-2 and iNOS in Microglial Cells

(2009) Won-Kyo Jung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiation

(2009) Soo-Jin Heo et al.   TOXICOLOGY IN VITRO

Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava

(2008) Murat Artan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells

(2008) Young-Hee Kang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy

(2008) J A McCubrey et al.   LEUKEMIA

Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: Role of suppressor of cytokine signaling

(2007) Se-Kwon Kim et al.   BIOMEDICINE & PHARMACOTHERAPY