RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients

Hsp27 Protects Adenocarcinoma Cells from UV-Induced Apoptosis by Akt and p21-Dependent Pathways of Survival

(2010) Ragu Kanagasabai et al.   MOLECULAR CANCER RESEARCH

Metastatic pancreatic cancer: Is gemcitabine still the best standard treatment? (Review)

(2010) Di Marco   ONCOLOGY REPORTS

Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma

(2009) Anxun Wang et al.   BMC CANCER

Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer

(2009) Yi Xia et al.   JOURNAL OF MEDICINAL CHEMISTRY

Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability

(2008) Se Hun Kang et al.   BMC CANCER

Altered expression of anti-apoptotic proteins in non-involved tissue from cancer-containing breasts

(2008) A. J. Batchelder et al.   BREAST CANCER RESEARCH AND TREATMENT

Expression of heat shock protein 27 and alpha-crystallins in human retinoblastoma after chemoreduction

(2008) S Kase et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

HSP27 regulates cell adhesion and invasion via modulation of focal adhesion kinase and MMP-2 expression

(2008) Joong-Won Lee et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Crystal structure of poxvirus thymidylate kinase: An unexpected dimerization has implications for antiviral therapy

(2008) C. Caillat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA